Human/Mouse OMgp Antibody

Catalog #: MAB1674
1 Citation Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB1674
MAB1674-SP

All OMgp Antibodies

Product Details

Citations (1)

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human/Mouse OMgp Antibody Summary

Species Reactivity

Human, Mouse

Specificity

Detects human and mouse OMgp in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100% cross‑reactivity with recombinant human OMgp is observed.

Source

Monoclonal Rat IgG₁ Clone # 240527

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse OMgp
Ile25-Ser420
Accession # Q63912

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration

Sample

Western Blot

1 µg/mL

Recombinant Human OMgp (Catalog # 1673-OM)
Recombinant Mouse OMgp (Catalog # 1674-MG)

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: OMgp

OMgp is a GPI-anchored protein derived from myelin. It is expressed on oligodendrocytes and neurons and binds to a receptor complex consisting of the Nogo receptor and the p75 neurotrophin receptor, NGF R. OMgp is active in the inhibition of axonal outgrowth as well as regeneration following injury.

Long Name

Oligodendrocyte-Myelin glycoprotein

Entrez Gene IDs

4974 (Human); 18377 (Mouse)

Alternate Names

oligodendrocyte myelin glycoprotein; OMG; OMgp; OMGPoligodendrocyte-myelin glycoprotein

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citation for Human/Mouse OMgp Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties.
Authors: Nishino, Jinsuke, Kim, Sunjung, Zhu, Yuan, Zhu, Hao, Morrison, Sean J
Elife, 2013-11-05;2(0):e00924.
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot