Mouse CD302/CLEC13A Antibody Summary
Met1-Cys165
Accession # Q9DCG2
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Detection of Mouse CD302/CLEC13A by Western Blot. Western blot shows lysates of RAW 264.7 mouse monocyte/macrophage cell line. PVDF Membrane was probed with 2 µg/mL of Mouse CD302/CLEC13A Monoclonal Antibody (Catalog # MAB64241) followed by HRP-conjugated Anti-Rat IgG Secondary Antibody (Catalog # HAF005). A specific band was detected for CD302/CLEC13A at approximately 30 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: CD302/CLEC13A
CD302, also known as CLEC13A and DCL-1, is a 35 kDa type I transmembrane glycoprotein in the C-type lectin family. CD302 is expressed on monocytes, macrophages, dendritic cells, and granulocytes. It contains one carbohydrate binding domain in its extracellular region and can mediate antigen uptake. In human Hodgkin’s disease, a fusion protein containing portions of CD302 and the ECD of DEC-205 is expressed on Reed-Sternberg cells. Within the ECD, mouse CD302 shares 82% and 92% aa sequence identity with human and rat CD302, respectively.
Product Datasheets
Citation for Mouse CD302/CLEC13A Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
1 Citation: Showing 1 - 1
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Liver-expressed Cd302 and Cr1l limit hepatitis C virus cross-species transmission to mice
Authors: RJP Brown, B Tegtmeyer, J Sheldon, T Khera, Anggakusum, D Todt, G Vieyres, R Weller, S Joecks, Y Zhang, S Sake, D Bankwitz, K Welsch, C Ginkel, M Engelmann, G Gerold, E Steinmann, Q Yuan, M Ott, FWR Vondran, T Krey, LJ Ströh, C Miskey, Z Ivics, V Herder, W Baumgärtne, C Lauber, M Seifert, AW Tarr, CP McClure, G Randall, Y Baktash, A Ploss, VLD Thi, E Michailidi, M Saeed, L Verhoye, P Meuleman, N Goedecke, D Wirth, CM Rice, T Pietschman
Sci Adv, 2020-11-04;6(45):.
Species: Mouse
Sample Types: Cell Lysates, Whole Cells
Applications: Flow Cytometry, IHC, Western Blot
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