Mouse UGRP1/SCGB3A2 Antibody Summary
Leu22-Leu139
Accession # Q920H1
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Detection of Mouse UGRP1/SCGB3A2 by Immunohistochemistry Basal cell (BC) subpopulations other than BC-1 and BC-2 are relatively rare and have no consistent spatial distribution in the adult tracheal epithelium.Representative tile scan pictures of adult mouse tracheal sections immunostained for KRT5, TRP63 and representative markers of Basal-proliferating (A), Basal-squamous (B), Basal-mesenchyme-like (C), and Basal-secretory (D). High magnification images are representative of specific BC subpopulations depicted in boxed areas along the anterior-posterior or dorsal-ventral axis of the tracheal epithelium. Scale bars: large panels of overview: 200 μm; small panels: 10 μm. Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/36178196), licensed under a CC-BY license. Not internally tested by R&D Systems.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: UGRP1/SCGB3A2
UGRP1 (also secretglobin gene family 3A2/SCGB3A2) is an 18 kDa, secreted nonglycosylated polypeptide that is a member of the Uteroglonin family, UGRP subfamily. Mouse UGRP1(isoform A) circulates as a 37 kDa homodimer. Its mature form is 70 amino acids in length. There are two large alternate splice forms termed B and C. UGRP1B is a secreted homodimer that shows a 22 aa insert between aa 84 and 85 of the short form. UGRP1C contains a 55 aa substitution for the C-terminal seven aa of the short form, predicting a 118 aa secreted form. The common portion of mature mouse UGRP1 (isoforms A, B and C) shares 86% and 81% aa identity with rat and human UGRP1, respectively.
Product Datasheets
Citations for Mouse UGRP1/SCGB3A2 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 4
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PRDM3/16 regulate chromatin accessibility required for NKX2-1 mediated alveolar epithelial differentiation and function
Authors: He, H;Bell, SM;Davis, AK;Zhao, S;Sridharan, A;Na, CL;Guo, M;Xu, Y;Snowball, J;Swarr, DT;Zacharias, WJ;Whitsett, JA;
Nature communications
Species: Transgenic Mouse
Sample Types: Whole Tissue
Applications: Immunohistochemistry -
Airway basal cells show regionally distinct potential to undergo metaplastic differentiation
Authors: Yizhuo Zhou, Ying Yang, Lihao Guo, Jun Qian, Jian Ge, Debora Sinner et al.
eLife
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Prominin 1 and Notch regulate ciliary length and dynamics in multiciliated cells of the airway epithelium.
Authors: Carlos S, Helu L, Jun Q et al.
iScience.
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An essential function for autocrine Hedgehog signaling in epithelial proliferation and differentiation in the trachea
Authors: Yin W, Liontos A, Koepke J et al.
bioRxiv
FAQs
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Secondary Antibodies
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