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Caspase-3: Products
Caspase-3 is a widely expressed dimeric peptidase that is the major executioner caspase, the primary downstream mediator of apoptotic-associated proteolysis. Caspase-3 cleaves multiple substrates including PARP, proIL-16, PKC-gamma and -delta, proCaspases-6, -7, and -9, and beta-Catenin.
Normally, it is an inactive, exclusively cytosolic homodimer. During apoptosis, however, proCaspase-3 is activated by cleavage into p20 and p12 subunits, and the p20 subunit is trimmed to yield a p17 subunit. Active Caspase-3 contains two p17 and two p12 subunits.
Products:
- Primary Antibodies
- Small Molecules
- Peptides
- Proteins & Enzymes
- Proteome Profiler Antibody Arrays
- ELISAs
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"Caspase-3" has 24 results in Products.
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Proteome Profiler Human Apoptosis Array Kit
Contains 4 membranes - each spotted in duplicate with 35 different apoptosis antibodies
Apoptosis Activator 2
Promotes apoptosome formation and activates caspase-9/caspase-3 pathway. Selectively induces tumor cell apoptosis
Proteome Profiler Mouse Apoptosis Array
Contains 8 membranes - each spotted in duplicate with 21 different apoptosis antibodies
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