Human IL1RAPL1 Antibody

Catalog #: MAB975 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB975
MAB975-SP

All IL1RAPL1 Antibodies

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Human IL1RAPL1 Antibody Summary

Species Reactivity

Human

Specificity

Detects human IL1RAPL1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) IL-1 RI, rhIL-1 RII, rhIL-1 RAcP, rhIL-1 R4, rhIL-1 R5, rhIL-1 Rrp2, rhIL-1 R7, or rhIL-1 RAPL2 is observed.

Source

Monoclonal Mouse IgG₁ Clone # 143116

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Mouse myeloma cell line NS0-derived recombinant human IL‑1 RAPL1/IL‑1 R8
Leu19-Thr357
Accession # Q9NZN1

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Label

Unconjugated

Applications

Recommended Concentration

Sample

Western Blot

1 µg/mL

Recombinant Human IL‑1 RAPL1/IL‑1 R8

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: IL1RAPL1

Interleukin 1 receptor accessory protein-like 1 (IL1RAPL1), also known as Oligophenin-4 (OPHN4) and three immunoglobulin domain containing IL‑1 receptor‑related 2 (TIGIRR-2), is a member of the IL-1 receptor superfamily. Defects in IL1R8 are the cause of mental retardation X-linked type 21 (MRX21).

Long Name

Interleukin 1 Receptor Accessory Protein-like 1

Entrez Gene IDs

11141 (Human); 331461 (Mouse); 317553 (Rat)

Alternate Names

IL1R8IL1RAPL; IL-1R9; IL1RAPL1; IL-1RAPL1; IL-1-RAPL-1; IL-1RAPL-1; IL1RAPL-1; interleukin 1 receptor accessory protein-like 1; interleukin 1 receptor-8; interleukin-1 receptor accessory protein-like 1; mental retardation, X-linked 10; MRX10; MRX21; MRX34; oligophrenin-4; OPHN4mental retardation, X-linked 21; Three immunoglobulin domain-containing IL-1 receptor-related 2; TIGIRR-2; TIGIRR-2mental retardation, X-linked 34; X-linked interleukin-1 receptor accessory protein-like 1