Human Kell Antibody

Catalog #: MAB1914 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB1914
MAB1914-SP

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Human Kell Antibody Summary

Species Reactivity

Human

Specificity

Detects human Kell in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human ECE-2, recombinant human Neprilysin, or recombinant mouse Kell is observed.

Source

Monoclonal Mouse IgG₁ Clone # 195031

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Kell
Asn68-Trp732
Accession # P23276

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration

Sample

Western Blot

1 µg/mL

Recombinant Human Kell

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Kell

Kell, a type II membrane glycoprotein, is linked through a single disulfide bond to XK, a putative membrane transporter. These two proteins constitute the Kell blood group system. Kell is a zinc metalloprotease of the neprilysin family that cleaves big endothelins.

Long Name

Zinc protease blood group antigen

Entrez Gene IDs

3792 (Human); 23925 (Mouse)

Alternate Names

CD238 antigen; CD238; EC 3.4.24.-; ECE3; KEL; kell blood group antigen; kell blood group glycoprotein; Kell blood group; Kell blood group, metalloendopeptidase; Kell blood group, metallo-endopeptidase; Kell