Human/Mouse/Rat CCK-AR Antibody Summary
Lys256-Glu267
Accession # P30551
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Applications
Recombinant Mouse CCK-A R
Recombinant Rat CCK-A R
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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CCK-A R in Rat Pancreas. CCK-A R was detected in perfusion fixed frozen sections of rat pancreas using 5 µg/mL Human/Mouse/Rat CCK-A R Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2680) overnight at 4 °C. Tissue was stained (red) and counterstained (green). View our protocol for Fluorescent IHC Staining of Frozen Tissue Sections.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: CCK-AR
The physiologic actions of the cholecystokinin (CCK) family of peptide hormones are mediated through two classes of G protein-coupled receptors, CCK-A R and CCK-B R. CCK-A R is a 428 amino acid protein with 7 putative transmembrane domains. This GPCR is involved in gallbladder contraction, insulin secretion, and has also been described in specific regions of the central nervous system. CCK-A R has been implicated in pancreatic tumorigenesis as well as the pathogenesis of eating disorders and drug addiction.
Product Datasheets
Citations for Human/Mouse/Rat CCK-AR Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 3
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A Novel CCK Receptor GPR173 Mediates Potentiation of GABAergic Inhibition
Authors: He L, Shi H, Zhang G et al.
The Journal of Neuroscience
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A Novel CCK Receptor GPR173 Mediates Potentiation of GABAergic Inhibition
Authors: He L, Shi H, Zhang G et al.
The Journal of Neuroscience
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In vitro analysis of the effects of cholecystokinin on rat brain stem motoneurons.
Authors: Zheng Z, Lewis MW, Travagli RA
Am. J. Physiol. Gastrointest. Liver Physiol., 2004-12-09;288(5):G1066-73.
Species: Rat
Sample Types: Whole Tissue
Applications: IHC-Fr
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