CRBN: Products

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Pomalidomide 4'-alkylC8-acid 

Cereblon ligand with alkyl linker and terminal acid for onward chemistry

Pomalidomide 4'-PEG4-acid 

Cereblon ligand with PEG linker and terminal acid for onward chemistry

CRBN PROTAC® 14a 

Cereblon Degrader (PROTAC®)

JH-XI-10-02 

CDK8 Degrader (PROTAC®)

FC 11 

Highly potent focal adhesion kinase (FAK) Degrader (PROTAC®)

Pomalidomide 4'-PEG2-azide 

Cereblon ligand with PEG linker and terminal azide for onward chemistry

Photo-lenalidomide-acid 

Functionalized photoswitchable cereblon ligand for Degraders

Thalidomide 4'-ether-alkylC2-acid 

Cereblon ligand with alkyl linker and terminal acid for onward chemistry

Thalidomide 4'-ether-alkylC3-acid 

Cereblon ligand with alkyl linker and terminal acid for onward chemistry

Thalidomide 4'-ether-alkylC4-acid 

Cereblon ligand with alkyl linker and terminal acid for onward chemistry

Thalidomide 4'-ether-alkylC5-acid 

Cereblon ligand with alkyl linker and terminal acid for onward chemistry

Thalidomide 4'-ether-alkylC6-acid 

Cereblon ligand with alkyl linker and terminal acid for onward chemistry

Thalidomide 4'-ether-alkylC7-acid 

Cereblon ligand with alkyl linker and terminal acid for onward chemistry

Thalidomide 4'-ether-alkylC8-acid 

Cereblon ligand with alkyl linker and terminal acid for onward chemistry

MS 154 

Potent and selective cereblon-recruiting Degrader (PROTAC®) of mutant EGFR

Thalidomide 4'-ether-alkylC8-amine 

Cereblon ligand with alkyl linker and terminal amine for onward chemistry

VH 032 amide-alkylC9-acid 

VHL ligand with alkyl linker and terminal acid for onward chemistry

CG 858 

Selective BRAF-V600E protein Degrader (uSMITE™)

CG 858-Neg 

Negative control for CG 858 (Cat. No. 7427)

Pomalidomide 4'-PEG3-azide 

Cereblon ligand with PEG linker and terminal azide for onward chemistry

Pomalidomide 4'-PEG4-azide 

Cereblon ligand with PEG linker and terminal azide for onward chemistry

Pomalidomide 4'-PEG5-azide 

Cereblon ligand with PEG linker and terminal azide for onward chemistry

Pomalidomide 4'-alkylC3-azide 

Cereblon ligand with alkyl linker and terminal azide for onward chemistry

Pomalidomide 4'-alkylC4-azide 

Cereblon ligand with alkyl linker and terminal azide for onward chemistry

Pomalidomide 4'-alkylC5-azide 

Cereblon ligand with alkyl linker and terminal azide for onward chemistry

Pomalidomide 4'-alkylC6-azide 

Cereblon ligand with alkyl linker and terminal azide for onward chemistry

Thalidomide, 5'-fluoro 

Fluoro functionalized Thalidomide; cereblon ligand for PROTACs

Pomalidomide 5'-piperazine 

Cereblon ligand with terminal piperazine for onward chemistry

Pomalidomide 5'-piperazine-4-methylpiperidine 

Cereblon ligand with terminal piperidine for onward chemistry

Pomalidomide 5'-fluoro-6'-piperazine 

Cereblon ligand with terminal piperazine for onward chemistry

Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine 

Cereblon ligand with terminal piperidine for onward chemistry

Lenalidomide 5'-piperazine 

Cereblon ligand with terminal piperazine for onward chemistry

Lenalidomide 4'-PEG1-azide 

Cereblon ligand with PEG linker and terminal azide for onward chemistry

Lenalidomide 4'-PEG2-azide 

Cereblon ligand with PEG linker and terminal azide for onward chemistry

Lenalidomide 4'-alkylC3-azide 

Cereblon ligand with alkyl linker and terminal azide for onward chemistry

Lenalidomide 4'-alkylC5-azide 

Cereblon ligand with alkyl linker and terminal azide for onward chemistry

Thalidomide 4'-ether-PEG1-azide 

Cereblon ligand with PEG linker and terminal azide for onward chemistry

Thalidomide 4'-ether-PEG2-azide 

Cereblon ligand with PEG linker and terminal azide for onward chemistry

Thalidomide 4'-ether-PEG3-azide 

Cereblon ligand with PEG linker and terminal azide for onward chemistry

Thalidomide 4'-ether-alkylC3-azide 

Cereblon ligand with alkyl linker and terminal azide for onward chemistry

Thalidomide 4'-ether-alkylC5-azide 

Cereblon ligand with alkyl linker and terminal azide for onward chemistry

Thalidomide 5'-amine-alkylC8-amine 

Cereblon ligand with alkyl linker and terminal amine for onward chemistry

Phenyl-glutarimide 4'-oxyacetic acid 

Functionalized cereblon ligand for PROTAC development

5-Amino-Thalidomide 

Cereblon ligand with amine on C5 for onward chemistry

N-methylated pomalidomide 

Functionalized cereblon ligand for generating Degrader negative controls; also used as Pomalidomide negative control

Pomalidomide 4'-alkylC10-amine 

Cereblon ligand with alkyl linker and terminal amine for onward chemistry

Thalidomide 5'-amine-alkylC10-amine 

Cereblon ligand with alkyl linker and terminal amine for onward chemistry

Thalidomide 5'-amine-PEG1-amine 

Cereblon ligand with PEG linker and terminal amine for onward chemistry

Thalidomide 5'-amine-PEG2-amine 

Cereblon ligand with PEG linker and terminal amine for onward chemistry

Thalidomide 5'-amine-PEG3-amine 

Cereblon ligand with PEG linker and terminal amine for onward chemistry
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