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Prototypical PI 3-kinase inhibitor; also inhibits other kinases
Potent, irreversible inhibitor of PI 3-kinase. Also inhibitor of PLK1
Non-selective PI 3-kinase inhibitor
Inhibitor of PI 3-kinase, mTOR and DNA-PK
PI 3-kinase inhibitor, more potent than LY 294002 (Cat. No. 1130)
Class III PI 3-kinase inhibitor; also inhibits autophagy
Potent and selective PI 3-kinase p110α inhibitor
PI 3-K/Akt/mTOR signaling inhibitor; blocks phosphorylation of Akt and p70S6K in vitro
Potent and selective PI 3-kinase β inhibitor
Dual PI 3-kinase and PDPK1 (PDK1) inhibitor
Potent and selective PI 3-Kβ inhibitor
Dual DNA-PK and PI 3-K inhibitor
Dual kinase inhibitor; inhibits PI 3-K family kinases
Highly potent PI 3-kinase inhibitor; also potent inhibitor of mTOR and DNA-PK
Inhibits proliferation and induces apoptosis selectively in pancreatic CSCs and cancer cell lines
Potent PI 3-Kinase δ isoform inhibitor
Potent PI3K inhibitor, also used in hPSCs mesendoderm differentiation