Human/Mouse OMgp Antibody

Catalog # Availability Size / Price Qty
MAB1674
MAB1674-SP
Product Details
Citations (1)
FAQs
Supplemental Products
Reviews

Human/Mouse OMgp Antibody Summary

Species Reactivity
Human, Mouse
Specificity
Detects human and mouse OMgp in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100% cross‑reactivity with recombinant human OMgp is observed.
Source
Monoclonal Rat IgG1 Clone # 240527
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse OMgp
Ile25-Ser420
Accession # Q63912
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
Recombinant Human OMgp (Catalog # 1673-OM)
Recombinant Mouse OMgp (Catalog # 1674-MG)

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: OMgp

OMgp is a GPI-anchored protein derived from myelin. It is expressed on oligodendrocytes and neurons and binds to a receptor complex consisting of the Nogo receptor and the p75 neurotrophin receptor, NGF R. OMgp is active in the inhibition of axonal outgrowth as well as regeneration following injury.

Long Name
Oligodendrocyte-Myelin glycoprotein
Entrez Gene IDs
4974 (Human); 18377 (Mouse)
Alternate Names
oligodendrocyte myelin glycoprotein; OMG; OMgp; OMGPoligodendrocyte-myelin glycoprotein

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Citation for Human/Mouse OMgp Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties.
    Authors: Nishino, Jinsuke, Kim, Sunjung, Zhu, Yuan, Zhu, Hao, Morrison, Sean J
    Elife, 2013-11-05;2(0):e00924.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot

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