Mouse ICAM-1/CD54 Antibody

Catalog # Availability Size / Price Qty
AF796
AF796-SP
ICAM‑1/CD54 in Mouse Testis.
5 Images
Product Details
Citations (88)
FAQs
Supplemental Products
Reviews (2)

Mouse ICAM-1/CD54 Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse ICAM-1 in direct ELISAs and Western blots. In direct ELISAs, approximately 20% cross-reactivity with recombinant rat ICAM-1 is observed, approximately 5% cross-reactivity with recombinant human (rh) ICAM-1 and rhICAM-3 is observed, and less than 1% cross-reactivity with recombinant mouse ICAM-2 is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse ICAM-1/CD54
Gln28-Asn485
Accession # Q3U8M7
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Endotoxin Level
<0.10 EU per 1 μg of the antibody by the LAL method.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Mouse ICAM‑1/CD54 Fc Chimera (Catalog # 796-IC)
Immunohistochemistry
5-15 µg/mL
See below
Adhesion Blockade
The adhesion of HSB2 human peripheral blood acute lymphoblastic leukemia cells (5 x 104 cells/well) to immobilized Recombinant Mouse ICAM-1 Fc Chimera (Catalog # 796-IC, 5 µg/mL, 100 µL/well) was maximally inhibited (80-100%) by 5 µg/mL of the antibody.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Immunohistochemistry ICAM-1/CD54 antibody in Mouse Testis by Immunohistochemistry (IHC-Fr). View Larger

ICAM‑1/CD54 in Mouse Testis. ICAM-1/CD54 was detected in perfusion fixed frozen sections of mouse testis using Goat Anti-Mouse ICAM-1/CD54 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF796) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to plasma membrane in Leydig cells. View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections.

Western Blot Detection of Mouse ICAM-1/CD54 by Western Blot View Larger

Detection of Mouse ICAM-1/CD54 by Western Blot Increased stress kinase signaling and JNK pathway-dependent cytokine and chemokine production by primary keratinocytes lacking BRAF and RAF1.(A) Reduced ERK phosphorylation and increased JNK/p38 activation in primary delta / delta ep2 keratinocytes stimulated with EGF and/or TNF alpha and IL1 beta for 15 min. (B) Increased cytokine and chemokine production in primary delta / delta ep2 keratinocytes treated with EGF, TNF alpha and IL1 beta for 24 hr. Cytokine and chemokine production was determined by multiplex analysis, except for TSLP which was quantified by ELISA. Data represent mean ± SEM of 3–5 biological replicates. (C–D) Cells were pretreated with D-JNKI1 inhibitors prior to stimulation with EGF, TNF alpha and IL1 beta for 15 min (C) or 24 hr (D). Data represent the mean ± SEM of technical replicates (n = 3). (E–F) Effect of shRNA-mediated Mlk3 silencing on ERK and JNK phosphorylation and ICAM1 expression (E; stimulation with EGF, TNF alpha and IL1 beta for 15 min) and on the expression of Ccl2 and Tslp mRNA (F; stimulation with EGF, TNF alpha and IL1 beta for 24 hr) by F/F2 and delta / delta ep2 keratinocytes. shRen, shRNA targeting Renilla, used as a control; sh1 and sh2, targeting Mlk3, binding sites nucleotide 2266–2285 and 2383–2402, respectively. The shRNAs were encoded by lentiviral vectors coexpressing GFP. GFP immunoblots are shown to confirm similar levels of infection in all samples. Data represent mean ± SEM of 4 biological replicates. Each keratinocyte culture represents a pool of three mice. Immunoblots are representative of three independent experiments. p1 = 0.041, p2 = 0.040, p3 = 1.89E-4, p4 = 0.018, p5 = 0.046, p6 = 0.020, p7 = 0.008, p8 = 0.016, p9 = 0.001, p10 = 0.018, p11 = 3.23E-4, p12 = 1.47E-4, p13 = 0.007, p14 = 0.03, p15 = 0.035, p16 = 0.023 and p17 = 0.046.DOI:https://dx.doi.org/10.7554/eLife.14012.018Compound knockdown (KD2) of BRAF and RAF1 induce the expression of inflammation markers by HaCat cells in a MLK3/JNK-dependent manner.(A) Reduced ERK and increased JNK/p38 activation in BRAF and RAF1 knockdown (KD2) HaCat cells stimulated with EGF, TNF alpha and IL1 beta for 15 min. (B) D-JNKI1 reduces ICAM1 and CCL2 (n = 4) expression in KD2 cells treated with TNF alpha. (C) MEKi induces ICAM1 and CCL2 (n = 3) expression in RAF1KD cells treated with TNF alpha. In (B–C), ICAM1 expression was measured after a 3 hr, CCL2 expression after a 24 hr treatment with TNF alpha. (D) Effect of MLK3 silencing on ERK and JNK phosphorylation in WT and KD2 cells stimulated as in (A). MLK3 was silenced using a pool of oligonucleotides targeting the following regions: 686–704; 1489–1507; 2122–2138; and 2348–2366. MLK3 KD cells stimulated as in (B–C) show a decrease in JNK activation, ICAM1 and CCL2 (n = 7) expression. Immunoblots are representative of three independent experiments. qPCR data represent mean ± SEM of three independent experiments run in duplicates (p1 = 4.62E-4, p2 = 0.013, p3 = 0.050, p4 = 8.60E-8, p5 = 0.050, p6 = 0.001, p7 = 0.001 and p8 = 0.012).DOI:https://dx.doi.org/10.7554/eLife.14012.019 Image collected and cropped by CiteAb from the following publication (https://elifesciences.org/articles/14012), licensed under a CC-BY license. Not internally tested by R&D Systems.

Western Blot Detection of Mouse ICAM-1/CD54 by Western Blot View Larger

Detection of Mouse ICAM-1/CD54 by Western Blot Increased stress kinase signaling and JNK pathway-dependent cytokine and chemokine production by primary keratinocytes lacking BRAF and RAF1.(A) Reduced ERK phosphorylation and increased JNK/p38 activation in primary delta / delta ep2 keratinocytes stimulated with EGF and/or TNF alpha and IL1 beta for 15 min. (B) Increased cytokine and chemokine production in primary delta / delta ep2 keratinocytes treated with EGF, TNF alpha and IL1 beta for 24 hr. Cytokine and chemokine production was determined by multiplex analysis, except for TSLP which was quantified by ELISA. Data represent mean ± SEM of 3–5 biological replicates. (C–D) Cells were pretreated with D-JNKI1 inhibitors prior to stimulation with EGF, TNF alpha and IL1 beta for 15 min (C) or 24 hr (D). Data represent the mean ± SEM of technical replicates (n = 3). (E–F) Effect of shRNA-mediated Mlk3 silencing on ERK and JNK phosphorylation and ICAM1 expression (E; stimulation with EGF, TNF alpha and IL1 beta for 15 min) and on the expression of Ccl2 and Tslp mRNA (F; stimulation with EGF, TNF alpha and IL1 beta for 24 hr) by F/F2 and delta / delta ep2 keratinocytes. shRen, shRNA targeting Renilla, used as a control; sh1 and sh2, targeting Mlk3, binding sites nucleotide 2266–2285 and 2383–2402, respectively. The shRNAs were encoded by lentiviral vectors coexpressing GFP. GFP immunoblots are shown to confirm similar levels of infection in all samples. Data represent mean ± SEM of 4 biological replicates. Each keratinocyte culture represents a pool of three mice. Immunoblots are representative of three independent experiments. p1 = 0.041, p2 = 0.040, p3 = 1.89E-4, p4 = 0.018, p5 = 0.046, p6 = 0.020, p7 = 0.008, p8 = 0.016, p9 = 0.001, p10 = 0.018, p11 = 3.23E-4, p12 = 1.47E-4, p13 = 0.007, p14 = 0.03, p15 = 0.035, p16 = 0.023 and p17 = 0.046.DOI:https://dx.doi.org/10.7554/eLife.14012.018Compound knockdown (KD2) of BRAF and RAF1 induce the expression of inflammation markers by HaCat cells in a MLK3/JNK-dependent manner.(A) Reduced ERK and increased JNK/p38 activation in BRAF and RAF1 knockdown (KD2) HaCat cells stimulated with EGF, TNF alpha and IL1 beta for 15 min. (B) D-JNKI1 reduces ICAM1 and CCL2 (n = 4) expression in KD2 cells treated with TNF alpha. (C) MEKi induces ICAM1 and CCL2 (n = 3) expression in RAF1KD cells treated with TNF alpha. In (B–C), ICAM1 expression was measured after a 3 hr, CCL2 expression after a 24 hr treatment with TNF alpha. (D) Effect of MLK3 silencing on ERK and JNK phosphorylation in WT and KD2 cells stimulated as in (A). MLK3 was silenced using a pool of oligonucleotides targeting the following regions: 686–704; 1489–1507; 2122–2138; and 2348–2366. MLK3 KD cells stimulated as in (B–C) show a decrease in JNK activation, ICAM1 and CCL2 (n = 7) expression. Immunoblots are representative of three independent experiments. qPCR data represent mean ± SEM of three independent experiments run in duplicates (p1 = 4.62E-4, p2 = 0.013, p3 = 0.050, p4 = 8.60E-8, p5 = 0.050, p6 = 0.001, p7 = 0.001 and p8 = 0.012).DOI:https://dx.doi.org/10.7554/eLife.14012.019 Image collected and cropped by CiteAb from the following publication (https://elifesciences.org/articles/14012), licensed under a CC-BY license. Not internally tested by R&D Systems.

Western Blot Detection of Mouse ICAM-1/CD54 by Western Blot View Larger

Detection of Mouse ICAM-1/CD54 by Western Blot Increased stress kinase signaling and JNK pathway-dependent cytokine and chemokine production by primary keratinocytes lacking BRAF and RAF1.(A) Reduced ERK phosphorylation and increased JNK/p38 activation in primary delta / delta ep2 keratinocytes stimulated with EGF and/or TNF alpha and IL1 beta for 15 min. (B) Increased cytokine and chemokine production in primary delta / delta ep2 keratinocytes treated with EGF, TNF alpha and IL1 beta for 24 hr. Cytokine and chemokine production was determined by multiplex analysis, except for TSLP which was quantified by ELISA. Data represent mean ± SEM of 3–5 biological replicates. (C–D) Cells were pretreated with D-JNKI1 inhibitors prior to stimulation with EGF, TNF alpha and IL1 beta for 15 min (C) or 24 hr (D). Data represent the mean ± SEM of technical replicates (n = 3). (E–F) Effect of shRNA-mediated Mlk3 silencing on ERK and JNK phosphorylation and ICAM1 expression (E; stimulation with EGF, TNF alpha and IL1 beta for 15 min) and on the expression of Ccl2 and Tslp mRNA (F; stimulation with EGF, TNF alpha and IL1 beta for 24 hr) by F/F2 and delta / delta ep2 keratinocytes. shRen, shRNA targeting Renilla, used as a control; sh1 and sh2, targeting Mlk3, binding sites nucleotide 2266–2285 and 2383–2402, respectively. The shRNAs were encoded by lentiviral vectors coexpressing GFP. GFP immunoblots are shown to confirm similar levels of infection in all samples. Data represent mean ± SEM of 4 biological replicates. Each keratinocyte culture represents a pool of three mice. Immunoblots are representative of three independent experiments. p1 = 0.041, p2 = 0.040, p3 = 1.89E-4, p4 = 0.018, p5 = 0.046, p6 = 0.020, p7 = 0.008, p8 = 0.016, p9 = 0.001, p10 = 0.018, p11 = 3.23E-4, p12 = 1.47E-4, p13 = 0.007, p14 = 0.03, p15 = 0.035, p16 = 0.023 and p17 = 0.046.DOI:https://dx.doi.org/10.7554/eLife.14012.018Compound knockdown (KD2) of BRAF and RAF1 induce the expression of inflammation markers by HaCat cells in a MLK3/JNK-dependent manner.(A) Reduced ERK and increased JNK/p38 activation in BRAF and RAF1 knockdown (KD2) HaCat cells stimulated with EGF, TNF alpha and IL1 beta for 15 min. (B) D-JNKI1 reduces ICAM1 and CCL2 (n = 4) expression in KD2 cells treated with TNF alpha. (C) MEKi induces ICAM1 and CCL2 (n = 3) expression in RAF1KD cells treated with TNF alpha. In (B–C), ICAM1 expression was measured after a 3 hr, CCL2 expression after a 24 hr treatment with TNF alpha. (D) Effect of MLK3 silencing on ERK and JNK phosphorylation in WT and KD2 cells stimulated as in (A). MLK3 was silenced using a pool of oligonucleotides targeting the following regions: 686–704; 1489–1507; 2122–2138; and 2348–2366. MLK3 KD cells stimulated as in (B–C) show a decrease in JNK activation, ICAM1 and CCL2 (n = 7) expression. Immunoblots are representative of three independent experiments. qPCR data represent mean ± SEM of three independent experiments run in duplicates (p1 = 4.62E-4, p2 = 0.013, p3 = 0.050, p4 = 8.60E-8, p5 = 0.050, p6 = 0.001, p7 = 0.001 and p8 = 0.012).DOI:https://dx.doi.org/10.7554/eLife.14012.019 Image collected and cropped by CiteAb from the following publication (https://elifesciences.org/articles/14012), licensed under a CC-BY license. Not internally tested by R&D Systems.

Western Blot Detection of Mouse ICAM-1/CD54 by Western Blot View Larger

Detection of Mouse ICAM-1/CD54 by Western Blot D-JNKI1 treatment rescues inflammation in delta / delta ep2 mice.Mice were treated with D-JNKI1 or TAT peptide (22 mg/kg i.p. at 10 days of age) and analyzed after 12 days (A) D-JNKI1 treatment prevents disease onset in delta / delta ep2 mice. Immunoblot of epidermal lysates showing the effect of D-JNKI1 on the phosphorylation and expression of the indicated proteins, quantified as in Figure 1F. ACTB is shown as a loading control. (B–D) Decreased eyelid inflammation, mast cells infiltration (B; TB+; quantified in the plot on the right), epidermal chemokine/cytokine levels (C) and activated T cells, B cells and dendritic cells in lymph nodes (D) in D-JNKI1-treated delta / delta ep2 mice. Scale bars, 25 µm. Data represent mean ± SEM (n = 3–5; p1 = 0.026, p2 = 0.042, p3 = 0.022, p4 = 0.048, p5 = 0.044, p6 = 0.020, p7 = 0.025, p8 = 0.018, p9 = 0.016, p10 = 0.014, p11 = 0.023, p12 = 0.011, p13 = 0.039, p14 = 0.049, p15 = 0.015, p16 = 0.003, p17 = 1.70E-4, p18 = 0.008, p19 = 0.008, p20 = 0.004, p21 = 0.003, p22 = 0.017, p23 = 0.026, p24 = 0.027, p25 = 0.005, p26 = 2.13E-6, p27 = 4.50E-8, p28 = 1.39E-5, p29 = 0.001, p30 = 0.001, p31 = 0.001, p32 = 0.023, p33 = 2.35E-4, p34 = 0.050, p35 = 0.002, p36 = 0.050 and p37 = 0.012).DOI:https://dx.doi.org/10.7554/eLife.14012.015K6 expression and epidermal chemokine and cytokine levels in D-JNKI1-treated mice.(A) K6 expression is indistinguishable in TAT or D-JNKI1 treated F/F2 and △/△ep2 littermates. Scale bars, 25 µm. (B) Inflammatory chemokines and cytokines in epidermal lysates of TAT or D-JNKI1-treated mice. Data represent mean ± SEM (n = 3–5; p1 = 0.005, p2 = 0.001, p3 = 0.043, p4 = 0.026, p5 = 0.032, p6 = 0.016 and p7 = 0.051).DOI:https://dx.doi.org/10.7554/eLife.14012.016The inflammatory phenotype of delta / delta ep2 mice is not rescued by MyD88, caspase 1/11, or TNF knockout.Macroscopic appearance, spleen and lymph node size and circulating blood cell analysis are shown for the indicated genotypes (A–C). (A) Representative pictures of 4 month old delta / delta ep2, delta / delta ep2 MyD88-/- and control animals. Plots on the right represent the ratio between total splenocytes or lymph node cell numbers and body weight (n = 3–4). (B) Representative pictures and hemogram of 4 month old delta / delta ep2, delta / delta ep2 caspase 1/11-/- and control animals (n = 5–6). (C) Representative pictures and hemogram of 4 month old delta / delta ep2, delta / delta ep2 TNF-/- and control animals (n = 4–5). The macroscopic appearance of at least ten mice per genotype was monitored. Data represent mean ± SEM. p1 = 0.041, p2 = 0.052, p3 = 0.024, p4 = 0.023, p5 = 0.026, p6 = 0.034, p7 = 0.023, p8 = 0.007, p9 = 0.031, p10 = 0.011, and p11 = 0.034.DOI:https://dx.doi.org/10.7554/eLife.14012.017 Image collected and cropped by CiteAb from the following publication (https://elifesciences.org/articles/14012), licensed under a CC-BY license. Not internally tested by R&D Systems.

Reconstitution Calculator

Reconstitution Calculator

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: ICAM-1/CD54

Intercellular Adhesion Molecule-1 (ICAM-1, CD54) binds the leukocyte integrins LFA-1 and Mac-1. ICAM-1 expression is weak on leukocytes, epithelial and resting endothelial cells, as well as some other cell types, but expression can be stimulated by IFN-gamma, TNF-alpha, IL-1 beta, and LPS. Mouse and human ICAM-1 share approximately 54% amino acid identity.

Soluble ICAM-1 is found in a biologically active form in serum, probably as a result of proteolytic cleavage from the cell surface, and is elevated in patients with various inflammatory syndromes such as septic shock, leukocyte adhesion deficiency syndrome (LAD), cancer, and transplantation.

References
  1. Pigott, R. and C. Power (1993) in The Adhesion Molecule Facts Book. Academic Press, p. 74.
  2. Siu, G. et al. (1989) J. Immunol. 143:3813.
  3. Ballantyne, C.M. et al. (1989) Nuc. Acid. Res. 17:5853.
Long Name
Intercellular Adhesion Molecule 1
Entrez Gene IDs
3383 (Human); 15894 (Mouse); 25464 (Rat)
Alternate Names
BB2; CD54 antigen; CD54; cell surface glycoprotein P3.58; human rhinovirus receptor; ICAM1; ICAM-1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule 1; Major group rhinovirus receptor; P3.58

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Citations for Mouse ICAM-1/CD54 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

88 Citations: Showing 1 - 10
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  1. Endothelial Msx1 transduces hemodynamic changes into an arteriogenic remodeling response
    Authors: Ine Vandersmissen, Sander Craps, Maarten Depypere, Giulia Coppiello, Nick van Gastel, Frederik Maes et al.
    Journal of Cell Biology
  2. ARID1A and PI3-kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion
    Authors: Mike R. Wilson, Jake J. Reske, Jeanne Holladay, Genna E. Wilber, Mary Rhodes, Julie Koeman et al.
    Nature Communications
  3. Apolipoprotein E receptor 2 deficiency decreases endothelial adhesion of monocytes and protects against autoimmune encephalomyelitis
    Authors: Calvier L, Manouchehri N, Sacharidou A et al.
    Science Immunology
  4. Social defeat promotes a reactive endothelium in a brain region-dependent manner with increased expression of key adhesion molecules, selectins and chemokines associated with the recruitment of myeloid cells to the brain
    Authors: Caroline M. Sawicki, Daniel B. McKim, Eric S. Wohleb, Brant L. Jarrett, Brenda F. Reader, Diana M. Norden et al.
    Neuroscience
  5. Lumbar Myeloid Cell Trafficking into Locomotor Networks after Thoracic Spinal Cord Injury
    Authors: Christopher N. Hansen, Diana M. Norden, Timothy D. Faw, Rochelle Deibert, Eric S. S.Wohleb, John F. Sheridan et al.
    Experimental Neurology
  6. Inhibition of the Akt1-mTORC1 Axis Alters Venous Remodeling to Improve Arteriovenous Fistula Patency.
    Authors: Guo Xiangjiang, Fereydooni Arash, Isaji Toshihiko et al.
    Scientific Reports
  7. Infiltration of peripheral immune cells into the olfactory bulb in a mouse model of acute nasal inflammation
    Authors: Hinami Asano, Sanae Hasegawa-Ishii, Ken Arae, Aki Obara, Geoffroy Laumet, Robert Dantzer et al.
    Journal of Neuroimmunology
  8. CAF1-knockout mice are more susceptive to lipopolysaccharide-induced acute lung injury
    Authors: Jia-Xin Shi, Jia-Shu Li, Rong Hu, Xiao-Min Li, Hong Wang
    Journal of Inflammation Research
  9. Effect of Rosiglitazone on Liver Structure and Function in Genetically Diabetic Akita Mice
    Authors: Bianca Hemmeryckx, Marijke Gaekens, David J. Gallacher, Hua Rong Lu, Henri Roger Lijnen
    Basic & Clinical Pharmacology & Toxicology
  10. Aedes aegypti salivary gland extract alleviates acute itching by blocking TRPA1 channels
    Authors: Anderson R. A. Cerqueira, Leandro Rodrigues, Silvia Abigail Coavoy-Sánchez, Simone A. Teixeira, Karla B. Feitosa, Erika Y. Taniguchi et al.
    Frontiers in Physiology
  11. Matrix metalloproteinase-9 in the initial injury after hepatectomy in mice
    Authors: Norifumi Ohashi, Tomohide Hori, Florence Chen, Sura Jermanus, Akimasa Nakao, Shinji Uemoto et al.
    World Journal of Gastroenterology
  12. Antiphospholipid antibodies induce proinflammatory and procoagulant pathways in endothelial cells
    Authors: Markos Patsouras, Eirini Alexopoulou, Spyros Foutadakis, Eirini Tsiki, Panagiota Karagianni, Marios Agelopoulos et al.
    Journal of Translational Autoimmunity
  13. Reelin Depletion Protects Against Atherosclerosis by Decreasing Vascular Adhesion of Leukocytes
    Authors: Laurent Calvier, Xunde Xian, Richard G. Lee, Anastasia Sacharidou, Chieko Mineo, Philip W. Shaul et al.
    Arteriosclerosis, Thrombosis, and Vascular Biology
  14. Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer
    Authors: Marcus Ruscetti, John P. Morris, Riccardo Mezzadra, James Russell, Josef Leibold, Paul B. Romesser et al.
    Cell
  15. STAT3/NF‑ kappa B decoy oligodeoxynucleotides inhibit atherosclerosis through regulation of the STAT/NF‑ kappa B signaling pathway in a mouse model of atherosclerosis
    Authors: Hyun-Jin An, Mi-Gyeong Gwon, Hyemin Gu, Seongjae Bae, Jaechan Leem, Jin Bae Lee et al.
    International Journal of Molecular Medicine
  16. Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils
    Authors: Yuanyuan Zhang, Tianxiao Liu, Zhiyong Deng, Wenqian Fang, Xian Zhang, Shuya Zhang et al.
    Advanced Science
  17. Single-cell transcriptomic atlas of taste papilla aging
    Authors: Ren, W;Li, W;Cha, X;Wang, S;Cai, B;Wang, T;Li, F;Li, T;Xie, Y;Xu, Z;Wang, Z;Liu, H;Yu, Y;
    Aging cell
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  18. Characterization of focused ultrasound blood-brain barrier disruption effect on inflammation as a function of treatment parameters
    Authors: Angolano, C;Hansen, E;Ajjawi, H;Nowlin, P;Zhang, Y;Thunemann, N;Ferran, C;Todd, N;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Tissue Homogenates, Whole Tissue
    Applications: Immunohistochemistry, Western Blot
  19. Kupffer Cell Inactivation Alters Endothelial Cell Adhesion Molecules in Cecal Ligation and Puncture-Induced Sepsis
    Authors: Manandhar, S;Gaddam, RR;Chambers, S;Bhatia, M;
    Biomolecules
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  20. Neural precursor cell delivery induces acute post-ischemic cerebroprotection, but fails to promote long-term stroke recovery in hyperlipidemic mice due to mechanisms that include pro-inflammatory responses associated with brain hemorrhages
    Authors: Yin, D;Wang, C;Qi, Y;Wang, YC;Hagemann, N;Mohamud Yusuf, A;Dzyubenko, E;Kaltwasser, B;Tertel, T;Giebel, B;Gunzer, M;Popa-Wagner, A;Doeppner, TR;Hermann, DM;
    Journal of neuroinflammation
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  21. Pharmacological Inhibition and Genetic Deletion of Cystathionine Gamma-Lyase in Mice Protects against Organ Injury in Sepsis: A Key Role of Adhesion Molecules on Endothelial Cells
    Authors: Manandhar, S;Chambers, S;Miller, A;Ishii, I;Bhatia, M;
    International journal of molecular sciences
    Species: Transgenic Mouse, Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  22. Macrophage-to-endothelial cell crosstalk by the cholesterol metabolite 27HC promotes atherosclerosis in male mice
    Authors: Yu, L;Xu, L;Chu, H;Peng, J;Sacharidou, A;Hsieh, HH;Weinstock, A;Khan, S;Ma, L;Durán, JGB;McDonald, J;Nelson, ER;Park, S;McDonnell, DP;Moore, KJ;Huang, LJ;Fisher, EA;Mineo, C;Huang, L;Shaul, PW;
    Nature communications
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  23. Partial Mural Cell Ablation Disrupts Coronary Vasculature Integrity and Induces Systolic Dysfunction
    Authors: Cornuault, L;Hérion, FX;Bourguignon, C;Rouault, P;Foussard, N;Alzieu, P;Chapouly, C;Gadeau, AP;Couffinhal, T;Renault, MA;
    Journal of the American Heart Association
    Species: Transgenic Mouse
    Sample Types: Tissue Homogenates, Whole Tissue
    Applications: Immunohistochemistry, Western Blot
  24. Production of Dermatophagoides farinae Having Low Bacterial Content Using Ampicillin
    Authors: Kim, JY;Yi, MH;Kim, M;Choi, JH;Lee, S;Yong, TS;
    Journal of immunology research
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  25. TMEM59 ablation leads to loss of olfactory sensory neurons and impairs olfactory functions via interaction with inflammation
    Authors: Z Ma, W Li, L Zhuang, T Wen, P Wang, H Yu, Y Liu, Y Yu
    Brain, Behavior, and Immunity, 2023-04-13;111(0):151-168.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  26. Lgr5+ cells are required and dynamically participate in olfactory epithelium regeneration: a revisiting shows Lgr5 expression in multiple cell lineages
    Authors: W Ren, Z Ma, L Wang, X Feng, H Yu, Y Yu
    Theranostics, 2022-07-18;12(13):5631-5644.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  27. Targeted BRD4 protein degradation by dBET1 ameliorates acute ischemic brain injury and improves functional outcomes associated with reduced neuroinflammation and oxidative stress and preservation of blood-brain barrier integrity
    Authors: L Liu, C Yang, BP Lavayen, RJ Tishko, J Larochelle, E Candelario
    Journal of Neuroinflammation, 2022-06-27;19(1):168.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  28. Novel role for caspase 1 inhibitor VX765 in suppressing NLRP3 inflammasome assembly and atherosclerosis via promoting mitophagy and efferocytosis
    Authors: Y Jin, Y Liu, L Xu, J Xu, Y Xiong, Y Peng, K Ding, S Zheng, N Yang, Z Zhang, L Li, L Tan, H Song, J Fu
    Cell Death & Disease, 2022-05-31;13(5):512.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  29. Pericyte Loss Leads to Capillary Stalling Through Increased Leukocyte-Endothelial Cell Interaction in the Brain
    Authors: YG Choe, JH Yoon, J Joo, B Kim, SP Hong, GY Koh, DS Lee, WY Oh, Y Jeong
    Frontiers in Cellular Neuroscience, 2022-03-11;16(0):848764.
    Species: Mouse
    Sample Types: Protein Lysates
    Applications: Western Blot
  30. Critical changes in hypothalamic gene networks in response to pancreatic cancer as found by single-cell RNA sequencing
    Authors: C Huisman, MA Norgard, PR Levasseur, SM Krasnow, MGP van der Wi, B Olson, DL Marks
    Molecular Metabolism, 2022-01-11;0(0):101441.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  31. Apolipoprotein E receptor 2 deficiency decreases endothelial adhesion of monocytes and protects against autoimmune encephalomyelitis
    Authors: Calvier L, Manouchehri N, Sacharidou A et al.
    Science Immunology
  32. Deficiency of peroxiredoxin 2 exacerbates angiotensin II-induced abdominal aortic aneurysm
    Authors: SJ Jeong, MJ Cho, NY Ko, S Kim, IH Jung, JK Min, SH Lee, JG Park, GT Oh
    Exp. Mol. Med., 2020-09-14;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  33. RNA-seq analysis of gene expression profiles in isolated stria vascularis from wild-type and Alport mice reveals key pathways underling Alport strial pathogenesis
    Authors: B Dufek, DT Meehan, D Delimont, K Wilhelm, G Samuelson, R Coenen, J Madison, E Doyle, B Smyth, G Phillips, MA Gratton, D Cosgrove
    PLoS ONE, 2020-08-21;15(8):e0237907.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  34. Exposure to Zinc Oxide Nanoparticles Disrupts Endothelial Tight and Adherens Junctions and Induces Pulmonary Inflammatory Cell Infiltration
    Authors: CM Chen, ML Wu, YC Ho, PY Gung, MH Tsai, AN Orekhov, IA Sobenin, P Lin, SF Yet
    Int J Mol Sci, 2020-05-13;21(10):.
    Species: Human
    Sample Types: Cell Lys
    Applications: Western Blot
  35. A Multivalent ICAM-1 Binding Nanoparticle which Inhibits ICAM-1 and LFA-1 Interaction Represents a New Tool for the Investigation of Autoimmune-Mediated Dry Eye
    Authors: PY Hsueh, Y Ju, A Vega, MC Edman, JA MacKay, SF Hamm-Alvar
    Int J Mol Sci, 2020-04-15;21(8):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  36. Cell-specific and athero-protective roles for RIPK3 in a murine model of atherosclerosis
    Authors: S Colijn, V Muthukumar, J Xie, S Gao, CT Griffin
    Dis Model Mech, 2020-01-24;13(1):.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  37. IgA1 deposition may induce NLRP3 expression and macrophage transdifferentiation of podocyte in IgA nephropathy
    Authors: W Peng, GQ Pei, Y Tang, L Tan, W Qin
    J Transl Med, 2019-12-03;17(1):406.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  38. Interleukin 1 alpha administration is neuroprotective and neuro-restorative following experimental ischemic stroke
    Authors: KE Salmeron, ME Maniskas, DN Edwards, R Wong, I Rajkovic, A Trout, AA Rahman, S Hamilton, JF Fraser, E Pinteaux, GJ Bix
    J Neuroinflammation, 2019-11-14;16(1):222.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  39. VCAM-1 Density and Tumor Perfusion Predict T-cell Infiltration and Treatment Response in Preclinical Models
    Authors: J Riegler, H Gill, A Ogasawara, M Hedehus, V Javinal, J Oeh, GZ Ferl, J Marik, S Williams, D Sampath, J Schartner, RAD Carano
    Neoplasia, 2019-09-11;21(10):1036-1050.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Neutralization
  40. Intermittent Hypoxia Activates Duration-Dependent Protective and Injurious Mechanisms in Mouse Lung Endothelial Cells
    Authors: P Wohlrab, L Soto-Gonza, T Benesch, MP Winter, IM Lang, K Markstalle, V Tretter, KU Klein
    Front Physiol, 2018-12-06;9(0):1754.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  41. Early and Late Protective Effect of Bone Marrow Mononuclear Cell Transplantation on Radiation-Induced Vascular Dysfunction and Skin Lesions
    Authors: V Holler, V Buard, T Roque, C Squiban, M Benderitte, S Flamant, R Tamarat
    Cell Transplant, 2018-11-09;0(0):9636897188103.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  42. Neurokinin-1 receptor antagonism improves postoperative neurocognitive disorder in mice.
    Authors: Li Z, Luo T, Ning X, Xiong C, Wu A
    Neurosci Lett, 2018-09-28;687(0):189-195.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  43. Complement activation contributes to perioperative neurocognitive disorders in mice
    Authors: C Xiong, J Liu, D Lin, J Zhang, N Terrando, A Wu
    J Neuroinflammation, 2018-09-04;15(1):254.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  44. Corticosterone Production during Repeated Social Defeat Causes Monocyte Mobilization from the Bone Marrow, Glucocorticoid Resistance and Neurovascular Adhesion Molecule Expression
    Authors: A Niraula, Y Wang, JP Godbout, JF Sheridan
    J. Neurosci., 2018-01-30;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  45. Suberanilohydroxamic Acid as a Pharmacological Kruppel-Like Factor 2 Activator That Represses Vascular Inflammation and Atherosclerosis
    Authors: Y Xu, S Xu, P Liu, M Koroleva, S Zhang, S Si, ZG Jin
    J Am Heart Assoc, 2017-11-30;6(12):.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  46. Interferon-? treatment in vitro elicits some of the changes in cathepsin S and antigen presentation characteristic of lacrimal glands and corneas from the NOD mouse model of Sj�gren's Syndrome
    Authors: Z Meng, W Klinngam, MC Edman, SF Hamm-Alvar
    PLoS ONE, 2017-09-13;12(9):e0184781.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  47. Nicotinamide mononucleotide attenuates brain injury after intracerebral hemorrhage by activating Nrf2/HO-1 signaling pathway
    Authors: CC Wei, YY Kong, GQ Li, YF Guan, P Wang, CY Miao
    Sci Rep, 2017-04-06;7(1):717.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  48. Plasminogen Activator Inhibitor-1 Protects Mice Against Cardiac Fibrosis by Inhibiting Urokinase-type Plasminogen Activator-mediated Plasminogen Activation
    Authors: KK Gupta, DL Donahue, MJ Sandoval-C, FJ Castellino, VA Ploplis
    Sci Rep, 2017-03-23;7(1):365.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  49. Epidermal RAF prevents allergic skin disease
    Elife, 2016-07-19;5(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  50. Neutrophil Extracellular Traps Accumulate in Peripheral Blood Vessels and Compromise Organ Function in Tumor-Bearing Animals.
    Authors: Cedervall J, Zhang Y, Huang H, Zhang L, Femel J, Dimberg A, Olsson A
    Cancer Res, 2015-06-12;75(13):2653-62.
  51. Platelet-driven leukotriene C4-mediated airway inflammation in mice is aspirin-sensitive and depends on T prostanoid receptors.
    Authors: Liu T, Garofalo D, Feng C, Lai J, Katz H, Laidlaw T, Boyce J
    J Immunol, 2015-04-22;194(11):5061-8.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  52. Abrogation of plasminogen activator inhibitor-1-vitronectin interaction ameliorates acute kidney injury in murine endotoxemia.
    Authors: Gupta K, Donahue D, Sandoval-Cooper M, Castellino F, Ploplis V
    PLoS ONE, 2015-03-23;10(3):e0120728.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  53. Low-dose irradiation affects expression of inflammatory markers in the heart of ApoE -/- mice.
    Authors: Mathias D, Mitchel R, Barclay M, Wyatt H, Bugden M, Priest N, Whitman S, Scholz M, Hildebrandt G, Kamprad M, Glasow A
    PLoS ONE, 2015-03-23;10(3):e0119661.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  54. Intercellular adhesion molecule-1 expression by skeletal muscle cells augments myogenesis.
    Authors: Goh Q, Dearth C, Corbett J, Pierre P, Chadee D, Pizza F
    Exp Cell Res, 2014-09-30;331(2):292-308.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC-Fr
  55. ICAM-1-based rabies virus vaccine shows increased infection and activation of primary murine B cells in vitro and enhanced antibody titers in-vivo.
    Authors: Norton, James E, Lytle, Andrew G, Shen, Shixue, Tzvetkov, Evgeni P, Dorfmeier, Corin L, McGettigan, James P
    PLoS ONE, 2014-01-29;9(1):e87098.
    Species: Hamster
    Sample Types: Cell Lysates
    Applications: Western Blot
  56. CD44-deficiency attenuates the immunologic responses to LPS and delays the onset of endotoxic shock-induced renal inflammation and dysfunction.
    Authors: Rampanelli, Elena, Dessing, Mark C, Claessen, Nike, Teske, Gwendoli, Joosten, Sander P, Pals, Steven T, Leemans, Jaklien, Florquin, Sandrine
    PLoS ONE, 2013-12-23;8(12):e84479.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  57. Peptide inhibitor of NF-kappaB translocation ameliorates experimental atherosclerosis.
    Authors: Mallavia B, Recio C, Oguiza A, Ortiz-Munoz G, Lazaro I, Lopez-Parra V, Lopez-Franco O, Schindler S, Depping R, Egido J, Gomez-Guerrero C
    Am J Pathol, 2013-04-16;182(5):1910-21.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  58. Skeletal muscle cells express ICAM-1 after muscle overload and ICAM-1 contributes to the ensuing hypertrophic response.
    Authors: Dearth C, Goh Q, Marino J, Cicinelli P, Torres-Palsa M, Pierre P, Worth R, Pizza F
    PLoS ONE, 2013-03-11;8(3):e58486.
    Species: Mouse
    Sample Types: Cell Lysates, Whole Cells, Whole Tissue
    Applications: ICC, IHC, Western Blot
  59. Biomarkers of disease and treatment in murine and cynomolgus models of chronic asthma.
    Authors: Louten J, Mattson JD, Malinao MC, Li Y, Emson C, Vega F, Wardle RL, Van Scott MR, Fick RB, McClanahan TK, de Waal Malefyt R, Beaumont M
    Biomark Insights, 2012-07-10;7(0):87-104.
    Species: Mouse
    Sample Types: BALF
    Applications: Western Blot
  60. Lung-targeted overexpression of the NF-kappaB member RelB inhibits cigarette smoke-induced inflammation.
    Authors: McMillan DH, Baglole CJ, Thatcher TH, Maggirwar S, Sime PJ, Phipps RP
    Am. J. Pathol., 2011-05-05;179(1):125-33.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  61. Increased expression of CXCR4 and integrin alphaM in hypoxia-preconditioned cells contributes to improved cell retention and angiogenic potency.
    Authors: Kubo M, Li TS, Kamota T, Ohshima M, Qin SL, Hamano K
    J. Cell. Physiol., 2009-08-01;220(2):508-14.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  62. The E-selectin ligand basigin/CD147 is responsible for neutrophil recruitment in renal ischemia/reperfusion.
    Authors: Kato N, Yuzawa Y, Kosugi T
    J. Am. Soc. Nephrol., 2009-05-14;20(7):1565-76.
    Species: Mouse
    Sample Types: Tissue Homogenates, Whole Tissue
    Applications: IHC-Fr, Western Blot
  63. Apelin prevents aortic aneurysm formation by inhibiting macrophage inflammation.
    Authors: Leeper NJ, Tedesco MM, Kojima Y, Schultz GM, Kundu RK, Ashley EA, Tsao PS, Dalman RL, Quertermous T
    Am. J. Physiol. Heart Circ. Physiol., 2009-03-20;296(5):H1329-35.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  64. Antigen-loaded ER microsomes from APC induce potent immune responses against viral infection.
    Authors: Sofra V, Mansour S, Liu M, Gao B, Primpidou E, Wang P, Li S
    Eur. J. Immunol., 2009-01-01;39(1):85-95.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  65. PPARgamma agonist rosiglitazone is neuroprotective after traumatic brain injury via anti-inflammatory and anti-oxidative mechanisms.
    Authors: Yi JH, Park SW, Brooks N, Lang BT, Vemuganti R
    Brain Res., 2008-10-09;1244(0):164-72.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  66. Plasminogen activator inhibitor-1 regulates neutrophil influx during acute pyelonephritis.
    Authors: Roelofs JJ, Teske GJ, Bonta PI, de Vries CJ, Meijers JC, Weening JJ, van der Poll T, Florquin S
    Kidney Int., 2008-09-17;75(1):52-9.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  67. Vascular inflammation, insulin resistance, and reduced nitric oxide production precede the onset of peripheral insulin resistance.
    Authors: Kim F, Pham M, Maloney E, Rizzo NO, Morton GJ, Wisse BE, Kirk EA, Chait A, Schwartz MW
    Arterioscler. Thromb. Vasc. Biol., 2008-09-04;28(11):1982-8.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  68. Atherosclerosis prevention by a fish oil-rich diet in apoE(-/-) mice is associated with a reduction of endothelial adhesion molecules.
    Authors: Casos K, Saiz MP, Ruiz-Sanz JI, Mitjavila MT
    Atherosclerosis, 2008-03-16;201(2):306-17.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  69. Dietary alpha-lipoic acid supplementation inhibits atherosclerotic lesion development in apolipoprotein E-deficient and apolipoprotein E/low-density lipoprotein receptor-deficient mice.
    Authors: Zhang WJ, Bird KE, McMillen TS, LeBoeuf RC, Hagen TM, Frei B
    Circulation, 2007-12-24;117(3):421-8.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  70. Fractalkine upregulates intercellular adhesion molecule-1 in endothelial cells through CX3CR1 and the Jak Stat5 pathway.
    Authors: Yang XP, Mattagajasingh S, Su S, Chen G, Cai Z, Fox-Talbot K, Irani K, Becker LC
    Circ. Res., 2007-09-20;101(10):1001-8.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  71. Crosstalk between keratinocytes and adaptive immune cells in an IkappaBalpha protein-mediated inflammatory disease of the skin.
    Authors: Rebholz B, Haase I, Eckelt B, Paxian S, Flaig MJ, Ghoreschi K, Nedospasov SA, Mailhammer R, Debey-Pascher S, Schultze JL, Weindl G, Forster I, Huss R, Stratis A, Ruzicka T, Rocken M, Pfeffer K, Schmid RM, Rupec RA
    Immunity, 2007-08-09;27(2):296-307.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  72. High pressure promotes monocyte adhesion to the vascular wall.
    Authors: Riou S, Mees B, Esposito B, Merval R, Vilar J, Stengel D, Ninio E, van Haperen R, de Crom R, Tedgui A, Lehoux S
    Circ. Res., 2007-03-29;100(8):1226-33.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  73. An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium.
    Authors: Johnson LA, Clasper S, Holt AP, Lalor PF, Baban D, Jackson DG
    J. Exp. Med., 2006-11-20;203(12):2763-77.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  74. Activation of mouse protease-activated receptor-2 induces lymphocyte adhesion and generation of reactive oxygen species.
    Authors: Lim SY, Tennant GM, Kennedy S, Wainwright CL, Kane KA
    Br. J. Pharmacol., 2006-09-18;149(5):591-9.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  75. Shedding of soluble ICAM-1 into the alveolar space in murine models of acute lung injury.
    Authors: Mendez MP, Morris SB, Wilcoxen S, Greeson E, Moore B, Paine R
    Am. J. Physiol. Lung Cell Mol. Physiol., 2005-12-22;290(5):L962-70.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  76. 5-Lipoxygenase Metabolite 4-HDHA Is a Mediator of the Antiangiogenic Effect of omega -3 Polyunsaturated Fatty Acids
    Authors: Przemyslaw Sapieha, Andreas Stahl, Jing Chen, Molly R. Seaward, Keirnan L. Willett, Nathan M. Krah et al.
    Science Translational Medicine
  77. Cell-Type-Specific Interleukin 1 Receptor 1 Signaling in the Brain Regulates Distinct Neuroimmune Activities
    Authors: Xiaoyu Liu, Daniel P. Nemeth, Daniel B. McKim, Ling Zhu, Damon J. DiSabato, Olimpia Berdysz et al.
    Immunity
  78. Microglia alter the threshold of spreading depolarization and related potassium uptake in the mouse brain
    Authors: Dániel P Varga, Ákos Menyhárt, Balázs Pósfai, Eszter Császár, Nikolett Lénárt, Csaba Cserép et al.
    Journal of Cerebral Blood Flow & Metabolism
  79. Homozygous Smpd1 deficiency aggravates brain ischemia/ reperfusion injury by mechanisms involving polymorphonuclear neutrophils, whereas heterozygous Smpd1 deficiency protects against mild focal cerebral ischemia
    Authors: Nina Hagemann, Ayan Mohamud Yusuf, Carlotta Martiny, Xiaoni Zhang, Christoph Kleinschnitz, Matthias Gunzer et al.
    Basic Research in Cardiology
  80. Interleukin-1 mediates ischaemic brain injury via distinct actions on endothelial cells and cholinergic neurons.
    Authors: Wong R, Lenart N, Hill L et al.
    Flow Cytometry Basics for the Non-Expert.
  81. Circulating soluble endoglin modifies the inflammatory response in mice
    Authors: L Ruiz-Remol, C Ollauri-Ib, L Pérez-Roqu, E Núñez-Góme, F Pérez-Barr, JM López-Novo, M Pericacho, A Rodríguez-
    PLoS ONE, 2017-11-16;12(11):e0188204.
  82. Re-purposing the pro-senescence properties of doxorubicin to introduce immunotherapy in breast cancer brain metastasis
    Authors: Rebeca Uceda-Castro, Andreia S. Margarido, Lesley Cornet, Serena Vegna, Kerstin Hahn, Ji-Ying Song et al.
    Cell Reports Medicine
  83. Helper-Dependent Adenovirus Transduces the Human and Rat Retina but Elicits an Inflammatory Reaction When Delivered Subretinally in Rats
    Authors: Ian C. Han, Erin R. Burnight, Mallory J. Ulferts, Kristan S. Worthington, Stephen R. Russell, Elliott H. Sohn et al.
    Human Gene Therapy
  84. Expression of intercellular adhesion molecule-1 by myofibers in mdx mice
    Authors: Maria J. Torres-Palsa, Matthew V. Koziol, Qingnian Goh, Peter A. Cicinelli, Jennifer M. Peterson, Francis X. Pizza
    Muscle & Nerve
  85. Neutrophil extracellular traps drive inflammatory pathogenesis in malaria.
    Authors: Knackstedt S L, Georgiadou A et al.
    Sci Immunol
  86. Effects of intra-abdominal sepsis on atherosclerosis in mice
    Authors: Ata Murat Kaynar, Sachin Yende, Lin Zhu, Daniel R Frederick, Robin Chambers, Christine L Burton et al.
    Critical Care
  87. Characterization of Influenza A Virus Infection in Mouse Pulmonary Stem/Progenitor Cells
    Authors: Tai-Ling Chao, Sing-Yi Gu, Pi-Han Lin, Yu-Tien Chou, Thai-Yen Ling, Sui-Yuan Chang
    Frontiers in Microbiology
  88. Age-associated pro-inflammatory adaptations of the mouse thoracic aorta
    Authors: Bianca Hemmeryckx, Marc F. Hoylaerts, Eveline Deloose, Cor E. Van Hove, Paul Fransen, Hidde Bult et al.
    Thrombosis and Haemostasis

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Mouse ICAM-1/CD54 Antibody
By Anonymous on 12/14/2022
Application: IHC Sample Tested: Breast cancer tissue,Lung tissue,Pancreas tissue,Spleen tissue Species: Mouse

paraffin-embedded tissue
Antigen Retrieval in citrate buffer pH 6
concentrations tested: 1:50-1:300 all worked


Mouse ICAM-1/CD54 Antibody
By Liming Yu on 01/19/2022
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Heart tissue Species: Mouse

Frozen section of aortic root with atherosclerotic lesion was stained with CD31/ICAM-1/DAPI after acetone fixing.