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Mouse MOG Antibody

Catalog #: AF2439
7 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
AF2439
AF2439-SP
MOG in Mouse Brain.
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Product Details
Citations (7)
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Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse MOG Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse MOG in direct ELISAs and Western blots. In direct ELISAs, less than 40% cross-reactivity with recombinant human MOG is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse MOG
Gly29-Gly153
Accession # Q61885
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Mouse MOG
Immunohistochemistry
5-15 µg/mL
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Immunohistochemistry MOG antibody in Mouse Brain by Immunohistochemistry (IHC-Fr). View Larger

MOG in Mouse Brain. MOG was detected in perfusion fixed frozen sections of mouse brain (cortex) using 15 µg/mL Goat Anti-Mouse MOG Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2439) overnight at 4 °C. Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: MOG

Mouse MOG is an integral membrane protein belonging to the immunoglobulin superfamily. It is found exclusively on myelinating oligodendrocytes in the central nervous system. The amino-terminal extracellular domain of mouse MOG shares 97% and 92% amino acid sequence identity with the corresponding regions of rat and human MOG, respectively.

Long Name
Myelin Oligodendrocyte Glycoprotein
Entrez Gene IDs
4340 (Human); 17441 (Mouse)
Alternate Names
MGC26137; MOG Ig-AluB; MOG; MOGIG2; myelin oligodendrocyte glycoprotein; myelin-oligodendrocyte glycoprotein

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Citations for Mouse MOG Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

7 Citations: Showing 1 - 7
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  1. Induction of antigen-specific tolerance by hepatic AAV immunotherapy regardless of T cell epitope usage or mouse strain background
    Authors: Geoffrey D. Keeler, Cristina D. Gaddie, Addelynn S. Sagadevan, Kevin G. Senior, Isabelle Côté, Michaela Rechdan et al.
    Molecular Therapy - Methods & Clinical Development
  2. Bazedoxifene, a Selective Estrogen Receptor Modulator, Promotes Functional Recovery in a Spinal Cord Injury Rat Model
    Authors: Yiyoung Kim, Eun Ji Roh, Hari Prasad Joshi, Hae Eun Shin, Hyemin Choi, Su Yeon Kwon et al.
    International Journal of Molecular Sciences
  3. Changes in the Oligodendrocyte Progenitor Cell Proteome with Ageing
    Authors: Alerie G. de la Fuente, Rayner M.L. Queiroz, Tanay Ghosh, Christopher E. McMurran, Juan F. Cubillos, Dwight E. Bergles et al.
    Molecular & Cellular Proteomics
  4. Contactin-1 regulates myelination and nodal/paranodal domain organization in the central nervous system.
    Authors: Colakoglu G, Bergstrom-Tyrberg U, Berglund E, Ranscht B
    Proc Natl Acad Sci U S A, 2014-01-02;111(3):E394-403.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  5. Ninjurin1 deficiency attenuates susceptibility of experimental autoimmune encephalomyelitis in mice.
    Authors: Ahn, Bum Ju, Le, Hoang, Shin, Min Wook, Bae, Sung-Jin, Lee, Eun Ji, Wee, Hee-Jun, Cha, Jong-Ho, Lee, Hyo-Jong, Lee, Hye Shin, Kim, Jeong Hu, Kim, Chang-Ye, Seo, Ji Hae, Lo, Eng H, Jeon, Sejin, Lee, Mi-Ni, Oh, Goo Taeg, Yin, Guo Nan, Ryu, Ji-Kan, Suh, Jun-Kyu, Kim, Kyu-Won
    J Biol Chem, 2013-12-17;289(6):3328-38.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  6. In vivo imaging of dorsal root regeneration: rapid immobilization and presynaptic differentiation at the CNS/PNS border.
    Authors: Di Maio A, Skuba A, Himes BT
    J. Neurosci., 2011-03-23;31(12):4569-82.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  7. Negative regulation of autoimmune demyelination by the inhibitory receptor CLM-1.
    Authors: Xi H, Katschke KJ, Helmy KY, Wark PA, Kljavin N, Clark H, Eastham-Anderson J, Shek T, Roose-Girma M, Ghilardi N, van Lookeren Campagne M
    J. Exp. Med., 2009-12-28;207(1):7-16, S1-5.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr

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