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Proteome Profiler Human XL Cytokine Array Kit

Catalog #: ARY022
157 Citations Datasheet / COA / SDS
Newer Version Available: ARY022B
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Contains 4 membranes - each spotted in duplicate with 102 different cytokine antibodies

Discontinued Product

ARY022 has been discontinued and is replaced by ARY022B.

R&D Systems Proteome Profiler Antibody Array Kits
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Proteome Profiler Human XL Cytokine Array Kit Summary

Proteome Profiler™ Human XL Cytokine Array Kit

A membrane-based antibody array for the parallel determination of the relative levels of selected human cytokines and chemokines.

 

Validated for analyte detection in cell culture supernates, cell lysates, tissue lysates, serum, plasma, human milk and saliva.

Key Benefits

  • Detects 102 human cytokines simultaneously
  • Requires no specialized equipment
  • Compatible with LI-COR and chemiluminescence detection
 

Principle of the Array

The Proteome Profiler Human XL Cytokine Array Kit is a membrane-based sandwich immunoassay. Capture antibodies spotted in duplicate on nitrocellulose membranes bind to specific target proteins present in the sample (Step 1). Captured proteins are detected with biotinylated detection antibodies (Step 2) and then visualized using chemiluminescent detection reagents (Step 3). The signal produced is proportional to the amount of analyte bound.

Why Use an Antibody Array to Detect Multiple Cytokines?

Determining the expression of multiple cytokines in a single sample can be expensive, time consuming and can require specialized equipment. Performing multiple immunoprecipitations and Western blots requires time, labor, and reagents. The use of a multiplex antibody array to detect multiple cytokines in a single sample can be cost-effective and also save time and sample.

Kit Contents

  • Rectangular 4-Well Multi-dish
  • 4 Human XL Cytokine Array nitrocellulose membranes spotted with 102 different antibodies to human cytokines
  • Array Buffer 4
  • Array Buffer 6
  • Chemi Reagent 1
  • Chemi Reagent 2
  • Detection Antibody Cocktail, Human XL Cytokine Array
  • Streptavidin-HRP
  • Transparency Overlay Template
  • Wash Buffer Concentrate (25X)

For a complete list of the kit contents and necessary materials, please see the Materials Provided/Other Supplies Required sections of the product datasheet.

 

Simultaneously detect the levels of these cytokines, chemokines, and acute phase proteins in a single sample.
Adiponectin/Acrp30 IFN-gamma Lipocalin-2/NGAL
Aggrecan IGFBP-2 CCL2/MCP-1
Angiogenin IGFBP-3 CCL7/MCP-3
Angiopoietin-1 IL-1 alpha/IL-1F1 M-CSF
Angiopoietin-2 IL-1 beta/IL-1F2 MIF
BAFF/BLyS/TNFSF13B IL-1ra/IL-1F3 CXCL9/MIG
BDNF IL-2 CCL3/CCL4 MIP-1 alpha/beta
CD14 IL-3 CCL20/MIP-3 alpha
CD30 IL-4 CCL19/MIP-3 beta
CD40 Ligand/TNFSF5 IL-5 MMP-9
Chitinase 3-like IL-6 Myeloperoxidase
Complement Component C5/C5a IL-8 Osteopontin (OPN)
Complement Factor D IL-10 PDGF-AA
C-Reactive Protein/CRP IL-11 PDGF-AB/BB
Cripto-1 IL-12 p70 Pentraxin 3/TSF-14
Cystatin C IL-13 CXCL4/PF4
Dkk-1 IL-15 RAGE
DPPIV/CD26 IL-16 CCL5/RANTES
EGF IL-17A RBP4
CXCL5/ENA-78 IL-18 BPa Relaxin-2
Endoglin/CD105 IL-19 Resistin
EMMPRIN IL-22 CXCL12/SDF-1 alpha
Fas Ligand IL-23 Serpin E1/PAI-1
FGF basic IL-24 SHBG
KGF/FGF-7 IL-27 ST2/IL1 R4
FGF-19 IL-31 CCL17/TARC
Flt-3 Ligand IL-32 alpha/beta/gamma TFF3
G-CSF IL-33 TfR
GDF-15 IL-34 TGF-alpha
GM-CSF CXCL10/IP-10 Thrombospondin-1
CXCL1/GRO alpha CXCL11/I-TAC TNF-alpha
Growth Hormone (GH) Kallikrein 3/PSA uPAR
HGF Leptin VEGF
ICAM-1/CD54 LIF Vitamin D BP

 

Stability and Storage

Store the unopened kit at 2°C to 8°C. Do not use past kit expiration date.

Data Examples

The Human XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates. Cells were untreated or treated as indicated below. 500 µL of cell culture supernate was run on each array. Data shown are from a 10 minute exposure to X-ray film. Profiles of mean spot pixel density were created using a transmission-mode scanner and image analysis software.

Figure 1A.
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Figure 1A. HUVEC human umbilical vein endothelial cells were untreated or treated with 100 µg/mL recombinant human TNF-alpha (Catalog #210-TA) for 24 hours.
Figure 1B
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Figure 1B. SW480 human colorectal adenocarcinoma cells were untreated or treated with 100 ng/mL of LPS for 24 hours.
Figure 1C
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Figure 1C. THP-1 human acute monocytic leukemia cells untreated or treated with 1 µg/mL of recombinant human IFN-gamma (Catalog #285-IF) for 16 hours and 1 µ/mL of LPS for 8 hours.

Specifications

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Species
Human

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Citations for Proteome Profiler Human XL Cytokine Array Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

157 Citations: Showing 1 - 10
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  1. Immunization with a multi-antigen targeted DNA vaccine eliminates chemoresistant pancreatic cancer by disrupting tumor-stromal cell crosstalk
    Authors: Qin, H;Chen, J;Bouchekioua-Bouzaghou, K;Meng, YM;Griera, JB;Jiang, X;Kong, X;Wang, M;Xu, Q;Wong, PP;
    Journal of translational medicine  2023-10-09
  2. miRNome and Proteome Profiling of Human Keratinocytes and Adipose Derived Stem Cells Proposed miRNA-Mediated Regulations of Epidermal Growth Factor and Interleukin 1-Alpha
    Authors: H Shahin, S Abdallah, J Das, W He, I El-Serafi, I Steinvall, F Sjöberg, M Elmasry, AT El-Serafi
    International Journal of Molecular Sciences, 2023-03-04;24(5):.  2023-03-04
  3. Extracellular Vesicles Derived from Three-Dimensional-Cultured Human Umbilical Cord Blood Mesenchymal Stem Cells Prevent Inflammation and Dedifferentiation in Pancreatic Islets
    Authors: E Lee, S Ha, G Kim, JH Kim, SM Jin
    Stem Cells International, 2023-02-20;2023(0):5475212.  2023-02-20
  4. gp120 Envelope Glycoproteins of HIV-1 Group M Subtype A and Subtype B Differentially Affect Gene Expression in Human Vascular Endothelial Cells
    Authors: AJ Suh, DI Suzuki, SG Gychka, TI Brelidze, YJ Suzuki
    International Journal of Molecular Sciences, 2023-02-10;24(4):.  2023-02-10
  5. Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury
    Authors: ME Mohr, S Li, AM Trouten, RA Stairley, PL Roddy, C Liu, M Zhang, HM Sucov, G Tao
    bioRxiv : the preprint server for biology, 2023-02-08;0(0):.  2023-02-08
  6. Tumor-secreted exosomal miR-141 activates tumor-stroma interactions and controls premetastatic niche formation in ovarian cancer metastasis
    Authors: Y Mo, LL Leung, CSL Mak, X Wang, WS Chan, LMN Hui, HWM Tang, MKY Siu, R Sharma, D Xu, SKW Tsui, HYS Ngan, MMH Yung, KKL Chan, DW Chan
    Molecular Cancer, 2023-01-09;22(1):4.  2023-01-09
  7. gp120 envelope glycoproteins of HIV-1 Group M Subtype A and Subtype B differentially affect gene expression in human vascular endothelial cells
    Authors: AJ Suh, DI Suzuki, SG Gychka, TI Brelidze, YJ Suzuki
    bioRxiv : the preprint server for biology, 2023-01-03;0(0):.  2023-01-03
  8. Pericytes take up and degrade alpha-synuclein but succumb to apoptosis under cellular stress
    Authors: TJ Stevenson, RH Johnson, J Savistchen, J Rustenhove, Z Woolf, LCD Smyth, HC Murray, RLM Faull, J Correia, P Schweder, P Heppner, C Turner, R Melki, BV Dieriks, MA Curtis, M Dragunow
    Scientific Reports, 2022-10-15;12(1):17314.  2022-10-15
  9. Fibrocytes boost tumor-supportive phenotypic switches in the lung cancer niche via the endothelin system
    Authors: A Weigert, X Zheng, A Nenzel, K Turkowski, S Günther, E Strack, E Sirait-Fis, E Elwakeel, IM Kur, VS Nikam, C Valasaraja, H Winter, A Wissgott, R Voswinkel, F Grimminger, B Brüne, W Seeger, SS Pullamsett, R Savai
    Nature Communications, 2022-10-14;13(1):6078.  2022-10-14
  10. The Differential Paracrine Role of the Endothelium in Prostate Cancer Cells
    Authors: V Torres-Est, M Mastri, S Rosario, P Fuenzalida, CE Echeverría, E Flores, A Watts, J Cerda-Infa, VP Montecinos, PC Sotomayor, J Amigo, C Escudero, F Nualart, JML Ebos, DJ Smiraglia, AS Godoy
    Cancers, 2022-09-29;14(19):.  2022-09-29
  11. The Nicotinic Receptor Polymorphism rs16969968 Is Associated with Airway Remodeling and Inflammatory Dysregulation in COPD Patients
    Authors: L Saber Cher, Z Diabasana, JM Perotin, J Ancel, LMG Petit, MA Devilliers, A Bonnomet, N Lalun, G Delepine, U Maskos, P Gosset, M Polette, A Muggeo, T Guillard, G Deslée, V Dormoy
    Cells, 2022-09-20;11(19):.  2022-09-20
  12. ADSCs stimulated by resistin promote breast cancer cell malignancy via CXCL5 in a breast cancer coculture model
    Authors: YY Wang, AC Hung, YC Wu, S Lo, HD Chen, YK Chen, YC Hsieh, SC Hu, MF Hou, SF Yuan
    Scientific Reports, 2022-09-14;12(1):15437.  2022-09-14
  13. Melanoma Mediated Disruption of Brain Endothelial Barrier Integrity Is Not Prevented by the Inhibition of Matrix Metalloproteinases and Proteases
    Authors: A Anchan, G Finlay, CE Angel, JJW Hucklesby, SE Graham
    Biosensors, 2022-08-19;12(8):.  2022-08-19
  14. During early stages of cancer, neutrophils initiate anti-tumor immune responses in tumor-draining lymph nodes
    Authors: E Pylaeva, G Korschunow, I Spyra, S Bordbari, E Siakaeva, I Ozel, M Domnich, A Squire, A Hasenberg, K Thangavelu, T Hussain, M Goetz, KS Lang, M Gunzer, W Hansen, J Buer, A Bankfalvi, S Lang, J Jablonska
    Cell Reports, 2022-08-16;40(7):111171.  2022-08-16
  15. Cell-Type Dependent Regulation of the Electrogenic Na+/HCO3- Cotransporter 1 (NBCe1) by Hypoxia and Acidosis in Glioblastoma
    Authors: M Giannaki, DE Ruf, E Pfeifer, K Everaerts, DH Heiland, O Schnell, CR Rose, E Roussa
    International Journal of Molecular Sciences, 2022-08-11;23(16):.  2022-08-11
  16. Plasmid-mediated gene transfer of Cas9 induces vector-related but not SpCas9-related immune responses in human retinal pigment epithelial cells
    Authors: JK Pfromm, M Bonillo, D Dauletbeko, K Bucher, MD Fischer
    Scientific Reports, 2022-08-01;12(1):13202.  2022-08-01
  17. Human iPSC co-culture model to investigate the interaction between microglia and motor neurons
    Authors: BF Vahsen, E Gray, A Candalija, KML Cramb, J Scaber, R Dafinca, A Katsikoudi, Y Xu, L Farrimond, R Wade-Marti, WS James, MR Turner, SA Cowley, K Talbot
    Scientific Reports, 2022-07-23;12(1):12606.  2022-07-23
  18. Neuropilin-2 axis in regulating secretory phenotype of neuroendocrine-like prostate cancer cells and its implication in therapy resistance
    Authors: R Islam, J Mishra, NS Polavaram, S Bhattachar, Z Hong, S Bodas, S Sharma, A Bouska, T Gilbreath, AM Said, LM Smith, BA Teply, MH Muders, SK Batra, K Datta, S Dutta
    Oncogene, 2022-07-19;40(3):111097.  2022-07-19
  19. Targeting HIC1/TGF-beta axis-shaped prostate cancer microenvironment restrains its progression
    Authors: T Wu, W Wang, G Shi, M Hao, Y Wang, M Yao, Y Huang, L Du, X Zhang, D Ye, X Bian, J Wang
    Cell Death & Disease, 2022-07-19;13(7):624.  2022-07-19
  20. Hepatocyte growth factor derived from senescent cells attenuates cell competition-induced apical elimination of oncogenic cells
    Authors: N Igarashi, K Miyata, TM Loo, M Chiba, A Hanyu, M Nishio, H Kawasaki, H Zheng, S Toyokuni, S Kon, K Moriyama, Y Fujita, A Takahashi
    Oncogene, 2022-07-18;13(1):4157.  2022-07-18
  21. Distinct airway epithelial immune responses after infection with SARS-CoV-2 compared to H1N1
    Authors: H Stölting, L Baillon, R Frise, K Bonner, RJ Hewitt, PL Molyneaux, ML Gore, Breathing, WS Barclay, S Saglani, CM Lloyd
    Mucosal Immunology, 2022-07-15;0(0):.  2022-07-15
  22. The human amniotic epithelium confers a bias to differentiate toward the neuroectoderm lineage in human embryonic stem cells
    Authors: D Ávila-Gonz, W Portillo, CP Barragán-Á, G Hernandez-, E Flores-Gar, A Molina-Her, NE Díaz-Martí, NF Díaz
    Elife, 2022-07-11;11(0):.  2022-07-11
  23. Interleukin-8 produced from cancer-associated fibroblasts suppresses proliferation of the OCUCh-LM1 cancer cell line
    Authors: R Tanaka, K Kimura, S Eguchi, G Ohira, S Tanaka, R Amano, H Tanaka, M Yashiro, M Ohira, S Kubo
    BMC Cancer, 2022-07-08;22(1):748.  2022-07-08
  24. The kinase activity of integrin-linked kinase regulates cellular senescence in gastric cancer
    Authors: C Ji, M Zhang, J Hu, C Cao, Q Gu, Y Liu, X Li, D Xu, L Ying, Y Yang, H Gao, J Li, L Yu
    Cell Death & Disease, 2022-07-01;13(7):577.  2022-07-01
  25. Two New Potential Therapeutic Approaches in Radiation Cystitis Derived from Mesenchymal Stem Cells: Extracellular Vesicles and Conditioned Medium
    Authors: C Helissey, N Guitard, H Théry, S Goulinet, P Mauduit, M Girleanu, AL Favier, M Drouet, C Parnot, C Chargari, S Cavallero, S François
    Biology, 2022-06-28;11(7):.  2022-06-28
  26. Serum biomarkers of neuroinflammation and blood-brain barrier leakage in amyotrophic lateral sclerosis
    Authors: MC Cao, EE Cawston, G Chen, C Brooks, J Douwes, D McLean, ES Graham, M Dragunow, EL Scotter
    BMC neurology, 2022-06-11;22(1):216.  2022-06-11
  27. Human Osteochondral Explants as an Ex Vivo Model of Osteoarthritis for the Assessment of a Novel Class of Orthobiologics
    Authors: C Giannasi, L Mangiavini, S Niada, A Colombo, E Della Mort, V Vismara, A Ambrosanio, P Savadori, S Casati, GM Peretti, AT Brini
    Pharmaceutics, 2022-06-10;14(6):.  2022-06-10
  28. Paclitaxel binds and activates C5aR1: A new potential therapeutic target for the prevention of chemotherapy-induced peripheral neuropathy and hypersensitivity reactions
    Authors: L Brandolini, M d'Angelo, R Novelli, V Castelli, C Giorgio, A Sirico, P Cocchiaro, F D'Egidio, E Benedetti, C Cristiano, A Bugatti, A Ruocco, PG Amendola, C Talarico, C Manelfi, D Iaconis, A Beccari, AU Quadros, TM Cunha, A Caruso, R Russo, A Cimini, A Aramini, M Allegretti
    Cell Death & Disease, 2022-05-25;13(5):500.  2022-05-25
  29. LCN2 is a new diagnostic biomarker and potential therapeutic target in idiopathic short stature
    Authors: X Liu, J Zhang, J Yuan, R Ding, T Liu, J Jia
    Journal of Cellular and Molecular Medicine, 2022-05-24;0(0):.  2022-05-24
  30. Ephrin B Activate Src Family Kinases in Fibroblasts Inducing Stromal Remodeling in Prostate Cancer
    Authors: M Kakarla, S ChallaSiva, MF Dufficy, V Gil, Y Filipovich, R Vickman, SE Crawford, SW Hayward, OE Franco
    Cancers, 2022-05-09;14(9):.  2022-05-09
  31. IFN-gamma and TNF Induce Senescence and a Distinct Senescence-Associated Secretory Phenotype in Melanoma
    Authors: L Homann, M Rentschler, E Brenner, K Böhm, M Röcken, T Wieder
    Cells, 2022-04-30;11(9):.  2022-04-30
  32. Preferential stimulation of melanocytes by M2 macrophages to produce melanin through vascular endothelial growth factor
    Authors: H Han, Y Kim, H Mo, SH Choi, K Lee, YA Rim, JH Ju
    Scientific Reports, 2022-04-19;12(1):6416.  2022-04-19
  33. ERalpha36-High Cancer-Associated Fibroblasts as an Unfavorable Factor in Triple-Negative Breast Cancer
    Authors: A Nagel, M Popeda, A Muchlinska, R Sadej, J Szade, J Zielinski, J Skokowski, M Niemira, A Kretowski, A Markiewicz, AJ Zaczek
    Cancers, 2022-04-15;14(8):.  2022-04-15
  34. Cancer-associated fibroblast-induced lncRNA UPK1A-AS1 confers platinum resistance in pancreatic cancer via efficient double-strand break repair
    Authors: X Zhang, S Zheng, C Hu, G Li, H Lin, R Xia, Y Ye, R He, Z Li, Q Lin, R Chen, Q Zhou
    Oncogene, 2022-03-09;0(0):.  2022-03-09
  35. Isolation of Platelet-Derived Exosomes from Human Platelet-Rich Plasma: Biochemical and Morphological Characterization
    Authors: M Saumell-Es, D Delgado, G García Del, M Beitia, J Sallés, I González-B, P Sánchez, M López de J, S Barrondo, M Sánchez
    International Journal of Molecular Sciences, 2022-03-05;23(5):.  2022-03-05
  36. Na�ve Human Macrophages Are Refractory to SARS-CoV-2 Infection and Exhibit a Modest Inflammatory Response Early in Infection
    Authors: Z Zhang, R Penn, WS Barclay, ES Giotis
    Viruses, 2022-02-21;14(2):.  2022-02-21
  37. Ibuprofen in Therapeutic Concentrations Affects the Secretion of Human Bone Marrow Mesenchymal Stromal Cells, but Not Their Proliferative and Migratory Capacity
    Authors: A Kulesza, K Zielniok, J Hawryluk, L Paczek, A Burdzinska
    Biomolecules, 2022-02-10;12(2):.  2022-02-10
  38. Analysis of gingival crevicular fluid biomarkers in patients with metabolic syndrome
    Authors: L Nibali, A Stephen, E Hagi-Pavli, R Allaker, AD Pino, V Terranova, M Pisano, SD Marca, V Ferrara, R Scicali, M Giordano, F Purrello, N Donos, L Malatino
    Journal of dentistry, 2022-02-06;118(0):104065.  2022-02-06
  39. Chemerin Overexpression in the Liver Protects against Inflammation in Experimental Non-Alcoholic Steatohepatitis
    Authors: R Pohl, S Feder, EM Haberl, L Rein-Fisch, TS Weiss, M Spirk, A Bruckmann, N McMullen, CJ Sinal, C Buechler
    Biomedicines, 2022-01-07;10(1):.  2022-01-07
  40. Comprehensive Molecular Landscape of Cetuximab Resistance in Head and Neck Cancer Cell Lines
    Authors: INF Gomes, RJ da Silva-O, LS da Silva, O Martinho, AF Evangelist, A van Helvoo, LF Leal, VAO Silva, SP Dos Santos, FC Nascimento, A Lopes Carv, RM Reis
    Cells, 2022-01-04;11(1):.  2022-01-04
  41. Diphenylarsinic acid induced activation of MAP kinases, transcription factors, and oxidative stress-responsive factors and hypersecretion of cytokines in cultured normal human cerebellar astrocytes
    Authors: S Sasaki, T Negishi, T Tsuzuki, K Yukawa
    Neurotoxicology, 2021-12-06;88(0):196-207.  2021-12-06
  42. Dynamic prostate cancer transcriptome analysis delineates the trajectory to disease progression
    Authors: M Bolis, D Bossi, A Vallerga, V Ceserani, M Cavalli, D Impellizzi, L Di Rito, E Zoni, S Mosole, AR Elia, A Rinaldi, R Pereira Me, E D'Antonio, M Ferrari, F Stoffel, F Jermini, S Gillessen, L Bubendorf, P Schraml, A Calcinotto, E Corey, H Moch, M Spahn, G Thalmann, M Kruithof-d, MA Rubin, JP Theurillat
    Nature Communications, 2021-12-02;12(1):7033.  2021-12-02
  43. C-C Motif Chemokine Ligand-17 as a Novel Biomarker and Regulator of Epithelial Mesenchymal Transition in Renal Fibrogenesis
    Authors: YH Hsieh, WC Wang, TW Hung, CC Lee, JP Tsai
    Cells, 2021-11-29;10(12):.  2021-11-29
  44. Reduction of Oxidative Stress in Peripheral Blood Mononuclear Cells Attenuates the Inflammatory Response of Fibroblast-like Synoviocytes in Rheumatoid Arthritis
    Authors: HR Lee, SJ Yoo, J Kim, CK Park, SW Kang
    International Journal of Molecular Sciences, 2021-11-17;22(22):.  2021-11-17
  45. Lnc-DC promotes estrogen independent growth and tamoxifen resistance in breast cancer
    Authors: WX Peng, P Koirala, H Zhou, J Jiang, Z Zhang, L Yang, YY Mo
    Cell Death & Disease, 2021-10-25;12(11):1000.  2021-10-25
  46. Cancer testis antigen PRAME: An anti-cancer target with immunomodulatory potential
    Authors: A Naik, R Thomas, G Al-Khadair, R Bacha, W Hendrickx, J Decock
    Journal of Cellular and Molecular Medicine, 2021-10-06;0(0):.  2021-10-06
  47. Inhibition of tumor progression and M2 microglial polarization by extracellular vesicle-mediated microRNA-124 in a 3D microfluidic glioblastoma microenvironment
    Authors: S Hong, JY You, K Paek, J Park, SJ Kang, EH Han, N Choi, S Chung, WJ Rhee, JA Kim
    Theranostics, 2021-09-27;11(19):9687-9704.  2021-09-27
  48. Circulating cytokines present in multiple myeloma patients inhibit the osteoblastic differentiation of adipose stem cells
    Authors: L Kobari, M Auclair, O Piau, N Ferrand, M Zaoui, F Delhommeau, B Fève, M Sabbah, L Garderet
    Leukemia, 2021-09-23;0(0):.  2021-09-23
  49. Metallothionein 2A Expression in Cancer-Associated Fibroblasts and Cancer Cells Promotes Esophageal Squamous Cell Carcinoma Progression
    Authors: M Shimizu, YI Koma, H Sakamoto, S Tsukamoto, Y Kitamura, S Urakami, K Tanigawa, T Kodama, N Higashino, M Nishio, M Shigeoka, Y Kakeji, H Yokozaki
    Cancers, 2021-09-10;13(18):.  2021-09-10
  50. Gelatin methacrylate hydrogels culture model for glioblastoma cells enriches for mesenchymal-like state and models interactions with immune cells
    Authors: N Shah, PM Hallur, RA Ganesh, P Sonpatki, D Naik, KP Chandracha, RB Puchalski, A Chaubey
    Scientific Reports, 2021-09-06;11(1):17727.  2021-09-06
  51. Electrophysiological engineering of heart-derived cells with calcium-dependent potassium channels improves cell therapy efficacy for cardioprotection
    Authors: P Vigneault, S Parent, P Kanda, C Michie, DR Davis, S Nattel
    Nature Communications, 2021-08-16;12(1):4963.  2021-08-16
  52. CD276 is an important player in macrophage recruitment into the tumor and an upstream regulator for PAI-1
    Authors: S Durlanik, K Fundel-Cle, C Viollet, HJ Huber, M Lenter, K Kitt, S Pflanz
    Scientific Reports, 2021-07-21;11(1):14849.  2021-07-21
  53. Transcryptomic Analysis of Human Brain -Microvascular Endothelial Cell Driven Changes in -Vascular Pericytes
    Authors: L Kurmann, M Okoniewski, RK Dubey
    Cells, 2021-07-14;10(7):.  2021-07-14
  54. Prophylactic role of Korean Red Ginseng in astrocytic mitochondrial biogenesis through HIF-1alpha
    Authors: J Park, M Lee, M Kim, S Moon, S Kim, S Kim, SH Koh, YM Kim, YK Choi
    Journal of Ginseng Research, 2021-07-12;46(3):408-417.  2021-07-12
  55. Altered Electrical, Biomolecular, and Immunologic Phenotypes in a Novel Patient-Derived Stem Cell Model of Desmoglein-2 Mutant ARVC
    Authors: RN Hawthorne, A Blazeski, J Lowenthal, S Kannan, R Teuben, D DiSilvestr, J Morrissett, JE Saffitz, KR Boheler, CA James, SP Chelko, G Tomaselli, L Tung
    Journal of Clinical Medicine, 2021-07-10;10(14):.  2021-07-10
  56. Combination of Epithelial Growth Factor Receptor Blockers and CDK4/6 Inhibitor for Nasopharyngeal Carcinoma Treatment
    Authors: HP Li, CY Huang, KW Lui, YK Chao, CN Yeh, LY Lee, Y Huang, TL Lin, YC Kuo, MY Huang, YR Lai, YM Yeh, HC Fan, AC Lin, JC Hsieh, KP Chang, CY Lin, HM Wang, YS Chang, CL Hsu
    Cancers, 2021-06-12;13(12):.  2021-06-12
  57. Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution
    Authors: LG Lima, S Ham, H Shin, EPZ Chai, ESH Lek, RJ Lobb, AF Müller, S Mathivanan, B Yeo, Y Choi, BS Parker, A Möller
    Nature Communications, 2021-06-10;12(1):3543.  2021-06-10
  58. CD109-GP130 interaction drives glioblastoma stem cell plasticity and chemoresistance through STAT3 activity
    Authors: P Filppu, JT Ramanathan, KJ Granberg, E Gucciardo, H Haapasalo, K Lehti, M Nykter, V Le Joncour, P Laakkonen
    JCI Insight, 2021-05-10;6(9):.  2021-05-10
  59. Transcryptomic Analysis of Human Brain-Microvascular Endothelial Response to -Pericytes: Cell Orientation Defines Barrier Function
    Authors: L Kurmann, M Okoniewski, OO Ogunshola, B Leeners, B Imthurn, RK Dubey
    Cells, 2021-04-20;10(4):.  2021-04-20
  60. Efficacy of chitinase-3-like protein 1 as an in�vivo bone formation predictable marker of maxillary/mandibular bone marrow stromal cells
    Authors: N Komabashir, F Suehiro, M Ishii, M Nishimura
    Regenerative Therapy, 2021-03-27;18(0):38-50.  2021-03-27
  61. Influence of serum inflammatory cytokines on cytochrome P450 drug metabolising activity during breast cancer chemotherapy: a patient feasibility study
    Authors: RLI Crake, MR Strother, E Phillips, MP Doogue, M Zhang, CMA Frampton, BA Robinson, MJ Currie
    Scientific Reports, 2021-03-11;11(1):5648.  2021-03-11
  62. Adhesion strength and contractility enable metastatic cells to become adurotactic
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