Neural Stem Cell Markers
Click on one of the stem cell types shown in the buttons below to see the markers that are commonly used to identify each cell type.
Overview
Neural stem cells (NSCs) are progenitor cells found in the central nervous system and peripheral nervous system. These multipotent, self-renewing cells give rise to all the cell types found in the central and peripheral nervous systems, including neurons, astrocytes, and oligodendrocytes. Levels of these progenitor cells play a role in nervous system development, neurodegenerative diseases, and neuroinflammation.
Data Examples
Verification of Neural Progenitor Marker Expression in Rat Neural Stem Cells. Rat cortical stem cells (R&D Systems, Catalog # NSC001) were assessed for expression of neural progenitor markers using the Human/Mouse/Rat Neural Progenitor Cell Marker Antibody Panel (R&D Systems, Catalog # SC025). Rat cortical stem cells were stained with A.) a Mouse Anti-CXCR4 Monoclonal Antibody followed by the NorthernLights™ (NL)557-conjugated Donkey Anti-Mouse Secondary Antibody (R&D Systems, Catalog # NL007; red), B.) a Goat Anti-Musashi-1 Antigen Affinity-purified Polyclonal Antibody followed by the NL557-conjugated Donkey Anti-Goat Secondary Antibody (R&D Systems, Catalog # NL001; red), and C.) a Mouse Anti-Nestin Monoclonal Antibody followed by the NL493-conjugated Donkey Anti-Mouse Secondary Antibody (R&D Systems, Catalog # NL009; green). The nuclei were counterstained with DAPI (blue) in each panel.
Verification of Neural Progenitor Marker Expression in Mouse Neural Stem Cells. Mouse cortical stem cells (R&D Systems, Catalog # NSC002) were assessed for expression of neural progenitor markers using the Human/Mouse/Rat Neural Progenitor Cell Marker Antibody Panel (R&D Systems, Catalog # SC025). Mouse cortical stem cells were stained with A.) a Mouse Anti-SSEA-1 Monoclonal Antibody followed by the NL557-conjugated Goat Anti-Mouse Secondary Antibody (R&D Systems, Catalog # NL019; red), B.) a Goat Anti-Notch-1 Antigen Affinity-purified Polyclonal Antibody followed by the NL493-conjugated Donkey Anti-Goat Secondary Antibody (R&D Systems, Catalog # NL003; green), and C.) a Goat Anti-SOX2 Antigen Affinity-purified Polyclonal Antibody followed by the NL557-conjugated Donkey Anti-Goat Secondary Antibody (R&D Systems, Catalog # NL001; red). The nuclei were counterstained with DAPI (blue) in each panel.