Human PIN Antibody

Catalog # Availability Size / Price Qty
AF877
AF877-SP
Product Details
Citations (4)
FAQs
Supplemental Products
Reviews

Human PIN Antibody Summary

Species Reactivity
Human
Specificity
Detects human PIN in direct ELISAs and Western blots.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant human PIN
Trp2-Gly89
Accession # P63167
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Human PIN
Immunohistochemistry
5-15 µg/mL
Immersion fixed paraffin-embedded sections of human ovary
Immunoprecipitation
2.5-5 µg/106 cells
HEK293 human embryonic kidney cell line, see our available Western blot detection antibodies

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Availability
Size / Price
Qty
RB01
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: PIN

PIN (protein inhibitor of neuronal nitric oxide synthase), also called DLC8, is an 8 kDa cytoplasmic protein that is a light chain of the dynein molecular motor.

Long Name
Protein Inhibitor of Neuronal Nitric Oxide Synthase
Entrez Gene IDs
8655 (Human)
Alternate Names
cytoplasmic dynein light polypeptide; DLC1; DLC1DNCLC1; DLC8; DLC8MGC126137; DNCL1; DNCL1MGC126138; DNCLC1; dynein light chain 1, cytoplasmic; Dynein light chain LC8-type 1; dynein, cytoplasmic, light polypeptide 1; dynein, light chain, LC8-type 1,8 kDa dynein light chain; DYNLL1; hdlc1; LC8; LC8a; PIN; PINLC8a; Protein inhibitor of neuronal nitric oxide synthase

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Citations for Human PIN Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

4 Citations: Showing 1 - 4
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  1. Dose-Dependent Biphasic Action of Quetiapine on AMPK Signalling via 5-HT7 Receptor: Exploring Pathophysiology of Clinical and Adverse Effects of Quetiapine
    Authors: M Okada, K Fukuyama, E Motomura
    International Journal of Molecular Sciences, 2022-08-14;23(16):.
    Species: Rat
    Sample Types: Cell Lysates
    Applications: Simple Western
  2. Brexpiprazole Reduces 5-HT7 Receptor Function on Astroglial Transmission Systems
    Authors: K Fukuyama, E Motomura, M Okada
    International Journal of Molecular Sciences, 2022-06-12;23(12):.
    Species: Rat
    Sample Types: Cell Lysates
    Applications: Simple Western
  3. Age-Dependent and Sleep/Seizure-Induced Pathomechanisms of Autosomal Dominant Sleep-Related Hypermotor Epilepsy
    Authors: Fukuyama K, Okada M.
    International Journal of Molecular Sciences
  4. Evaluation of an LC8-binding peptide for the attachment of artificial cargo to dynein.
    Authors: Bergen JM, Pun SH
    Mol. Pharm., 2007-01-01;4(1):119-28.
    Species: Human
    Sample Types: Peptide
    Applications: ELISA Development

FAQs

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Isotype Controls

Reconstitution Buffers

Secondary Antibodies

Goat IgG (H+L) Antibody

WB,Secondary

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