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Human Cornulin Antibody

Catalog #: AF3607
1 Citation Datasheet / COA / SDS
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AF3607
AF3607-SP
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Citations (1)
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human Cornulin Antibody Summary

Species Reactivity
Human
Specificity
Detects human Cornulin in direct ELISAs and Western blots.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant human Cornulin
Met1-Ser140
Accession # Q9UBG3
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Human Cornulin

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Cornulin

Cornulin, the product of the C1orf 10 gene found in the epidermal differentiation complex (EDC), is a 70 kDa protein that is expressed primarily in the upper layers of differentiated squamous tissues. It is a member of the “fused gene” family and contains two EF-hand Ca2+-binding domains in its amino-terminal region and two Thr/Glu-rich repeats in its C-terminal region. Over the region used as the immunogen, human and mouse Cornulin share 73% amino acid sequence identity.

Entrez Gene IDs
49860 (Human); 381457 (Mouse); 295186 (Rat)
Alternate Names
53 kDa squamous epithelial-induced stress protein; 58 kDa heat shock protein; C1orf10; chromosome 1 open reading frame 10; Cornulin; CRNN; DRC1; Gm1015; PDRC1; PDRC1,53 kDa putative calcium-binding protein; SEP53; SEP53C1orf10; Squamous epithelial heat shock protein 53; Tumor-related protein

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Citation for Human Cornulin Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Patient-Derived Organotypic Epithelial Rafts Model Phenotypes in Juvenile-Onset Recurrent Respiratory Papillomatosis
    Authors: MC Bedard, MG Brusadelli, A Carlile, S Ruiz-Torre, H Lodin, D Lee, M Kofron, PF Lambert, A Lane, N Ameziane, EM Bahassi, KA Wikenheise, A de Alarcon, DF Smith, SI Wells
    Viruses, 2021-01-06;13(1):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC

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