Home / VE-Cadherin / Mouse VE-Cadherin Antibody

Mouse VE-Cadherin Antibody

Catalog #: AF1002
118 Citations 1 Review Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
AF1002
AF1002-SP
Best Seller
Detection of Mouse VE‑Cadherin by Western Blot.
24 Images
Product Details
Citations (118)
FAQs
Supplemental Products
Reviews (1)
Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse VE-Cadherin Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse VE-Cadherin in direct ELISAs and Western blots. In direct ELISAs, approximately 30% cross‑reactivity with recombinant human VE-Cadherin is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse VE-Cadherin
Asp46-Gln592
Accession # 2208309A
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. See Certificate of Analysis for details.
*Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
0.2 µg/mL
See below
Simple Western
10 µg/mL
See below
Immunohistochemistry
3-25 µg/mL
See below
Dual RNAscope ISH-IHC
5-15 µg/mL
Immersion fixed paraffin-embedded sections of mouse heart

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Western Blot Detection of Mouse VE‑Cadherin antibody by Western Blot. View Larger

Detection of Mouse VE‑Cadherin by Western Blot. Western blot shows lysates of mouse lung tissue and bEnd.3 mouse endothelioma cell line. PVDF membrane was probed with 0.2 µg/mL of Goat Anti-Mouse VE‑Cadherin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1002) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017). A specific band was detected for VE‑Cadherin at approximately 120 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Immunohistochemistry VE-Cadherin antibody in Mouse Heart by Immunohistochemistry (IHC-P). View Larger

VE‑Cadherin in Mouse Heart. VE-Cadherin was detected in immersion fixed paraffin-embedded sections of mouse heart using Goat Anti-Mouse VE-Cadherin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1002) at 3 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC004). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cell membranes. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.

Simple Western Detection of Mouse VE-Cadherin antibody by Simple Western<sup>TM</sup>. View Larger

Detection of Mouse VE‑Cadherin by Simple WesternTM. Simple Western lane view shows lysates of mouse lung tissue, loaded at 0.2 mg/mL. Specific bands were detected for VE‑Cadherin at approximately 118, 146 kDa (as indicated) using 10 µg/mL of Goat Anti-Mouse VE‑Cadherin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1002). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.

Immunocytochemistry/ Immunofluorescence Detection of Mouse VE-Cadherin by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse VE-Cadherin by Immunocytochemistry/Immunofluorescence Resting skin vessels contain high density HS moieties preferentially expressed at their basolateral compartments.(A, C, E, F, G) Axial and longitudinal sections of vessels of (A, B) naïve frozen, or (C, D, E, F, G) paraffin embedded murine flank skin tissues. Tissues were stained for HS with monoclonal mouse IgM (10E4 epitope; red), goat anti mouse VE-cadherin (cyan), FITC-mouse monoclonal to alpha -SMA (green), and nuclei (blue). (H) HS and alpha -SMA profile of the fluorescence intensity along the purple arrow in the merged image. Double-headed black arrow denotes the vessel lumen as indicated by VE-cadherin. In C, D and G, small-headed arrows denote the endothelial apical side, large-headed arrows denote the endothelial basolateral side, and broken-line arrows denote the pericyte basolateral side. Images were taken at 100X magnification. Scale bar represents 5 µm. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0085699), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunohistochemistry Detection of Rat VE-Cadherin by Immunohistochemistry View Larger

Detection of Rat VE-Cadherin by Immunohistochemistry Chronic intermittent hypoxia modifies the BM vascular structure. a’–e’ Representative images of femur bone marrow stained with vWF, CD105, VE-cadherin, SMA, and CD11b counterstained with hematoxylin. a”, c”, d” BM from CIH exposed rats (n = 6) has more VE-cadherin+ vessels and SMA coverage but less vWF+ sinusoids (400×, Leica DM2500). e’, e” Representative images of CD11b immunohistochemistry in femur BM show an increase in BM monocyte count in CIH exposed animals. (400×, Leica DM2500) a’, a”’, b’, b” No changes in the total number of vessels or in megakaryocyte count were observed, as accounted by CD105 and vWF staining, respectively. Results are represented as the mean ± SD of bone marrow sections from six male Wistar rats (*p < 0.05; **p < 0.01). f Representative images of femur bone marrow fluorescently immunostained for VE-cadherin show an increase in total VE-cadherin vessels and in VE-cadherin vessel coverage. Scale bar, 50 μm (insets magnified 2.5×). Images were acquired with a Zeiss LSM 510 META microscope Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/26856724), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse VE-Cadherin by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse VE-Cadherin by Immunocytochemistry/Immunofluorescence Resting skin vessels contain high density HS moieties preferentially expressed at their basolateral compartments.(A, C, E, F, G) Axial and longitudinal sections of vessels of (A, B) naïve frozen, or (C, D, E, F, G) paraffin embedded murine flank skin tissues. Tissues were stained for HS with monoclonal mouse IgM (10E4 epitope; red), goat anti mouse VE-cadherin (cyan), FITC-mouse monoclonal to alpha -SMA (green), and nuclei (blue). (H) HS and alpha -SMA profile of the fluorescence intensity along the purple arrow in the merged image. Double-headed black arrow denotes the vessel lumen as indicated by VE-cadherin. In C, D and G, small-headed arrows denote the endothelial apical side, large-headed arrows denote the endothelial basolateral side, and broken-line arrows denote the pericyte basolateral side. Images were taken at 100X magnification. Scale bar represents 5 µm. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0085699), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse VE-Cadherin by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse VE-Cadherin by Immunocytochemistry/Immunofluorescence Resting skin vessels contain high density HS moieties preferentially expressed at their basolateral compartments.(A, C, E, F, G) Axial and longitudinal sections of vessels of (A, B) naïve frozen, or (C, D, E, F, G) paraffin embedded murine flank skin tissues. Tissues were stained for HS with monoclonal mouse IgM (10E4 epitope; red), goat anti mouse VE-cadherin (cyan), FITC-mouse monoclonal to alpha -SMA (green), and nuclei (blue). (H) HS and alpha -SMA profile of the fluorescence intensity along the purple arrow in the merged image. Double-headed black arrow denotes the vessel lumen as indicated by VE-cadherin. In C, D and G, small-headed arrows denote the endothelial apical side, large-headed arrows denote the endothelial basolateral side, and broken-line arrows denote the pericyte basolateral side. Images were taken at 100X magnification. Scale bar represents 5 µm. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0085699), licensed under a CC-BY license. Not internally tested by R&D Systems.

Flow Cytometry Detection of Mouse VE-Cadherin by Flow Cytometry View Larger

Detection of Mouse VE-Cadherin by Flow Cytometry FACS analysis of emerging vascular EC progenies from mES and iPS cells.Adherent cells (2x105) were detached and subjected to two-step FACS-aided purification. Control FACS profile on day 5 of cells derived from mES (J1) cells (A). Representative FACS profiles of day 5, with vascular progenies assessed using anti-Flk1 and anti-VE-cadherin antibodies obtained from mES (J1) cells (B) and derived from miPS (iMZ-21) cells (C); Control FACS profile on day 5 of cells derived from miPS (iMZ-21) cells (D). Representative FACS after the second step of purification derived from mES (E) and iPS cells (F). The yield of Flk1+VE-cadherin+ after the second round of FACS was 100% for both mES and miPS-derived vascular progenies. Morphology of mES- and miPS-derived vascular ECs (G-J). Flk1+VE-cadherin+ vascular progenies derived from mES and miPS cells were cultured overnight in IV Col-coated dishes, immunostained with anti-VE-cadherin (green) and anti-CD31 (red) of cells derived from mES cells (G&H) and miPS cells (I&J). DAPI, nucleus (blue). Magnifications are as indicated; the scale bar is 200 µm. Experiments were repeated 3 times. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0085549), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse VE-Cadherin by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse VE-Cadherin by Immunocytochemistry/Immunofluorescence Resting skin vessels contain high density HS moieties preferentially expressed at their basolateral compartments.(A, C, E, F, G) Axial and longitudinal sections of vessels of (A, B) naïve frozen, or (C, D, E, F, G) paraffin embedded murine flank skin tissues. Tissues were stained for HS with monoclonal mouse IgM (10E4 epitope; red), goat anti mouse VE-cadherin (cyan), FITC-mouse monoclonal to alpha -SMA (green), and nuclei (blue). (H) HS and alpha -SMA profile of the fluorescence intensity along the purple arrow in the merged image. Double-headed black arrow denotes the vessel lumen as indicated by VE-cadherin. In C, D and G, small-headed arrows denote the endothelial apical side, large-headed arrows denote the endothelial basolateral side, and broken-line arrows denote the pericyte basolateral side. Images were taken at 100X magnification. Scale bar represents 5 µm. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0085699), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse VE-Cadherin by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse VE-Cadherin by Immunocytochemistry/Immunofluorescence Resting skin vessels contain high density HS moieties preferentially expressed at their basolateral compartments.(A, C, E, F, G) Axial and longitudinal sections of vessels of (A, B) naïve frozen, or (C, D, E, F, G) paraffin embedded murine flank skin tissues. Tissues were stained for HS with monoclonal mouse IgM (10E4 epitope; red), goat anti mouse VE-cadherin (cyan), FITC-mouse monoclonal to alpha -SMA (green), and nuclei (blue). (H) HS and alpha -SMA profile of the fluorescence intensity along the purple arrow in the merged image. Double-headed black arrow denotes the vessel lumen as indicated by VE-cadherin. In C, D and G, small-headed arrows denote the endothelial apical side, large-headed arrows denote the endothelial basolateral side, and broken-line arrows denote the pericyte basolateral side. Images were taken at 100X magnification. Scale bar represents 5 µm. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0085699), licensed under a CC-BY license. Not internally tested by R&D Systems.

Flow Cytometry Detection of Mouse VE-Cadherin by Flow Cytometry View Larger

Detection of Mouse VE-Cadherin by Flow Cytometry FACS analysis of emerging vascular EC progenies from mES and iPS cells.Adherent cells (2x105) were detached and subjected to two-step FACS-aided purification. Control FACS profile on day 5 of cells derived from mES (J1) cells (A). Representative FACS profiles of day 5, with vascular progenies assessed using anti-Flk1 and anti-VE-cadherin antibodies obtained from mES (J1) cells (B) and derived from miPS (iMZ-21) cells (C); Control FACS profile on day 5 of cells derived from miPS (iMZ-21) cells (D). Representative FACS after the second step of purification derived from mES (E) and iPS cells (F). The yield of Flk1+VE-cadherin+ after the second round of FACS was 100% for both mES and miPS-derived vascular progenies. Morphology of mES- and miPS-derived vascular ECs (G-J). Flk1+VE-cadherin+ vascular progenies derived from mES and miPS cells were cultured overnight in IV Col-coated dishes, immunostained with anti-VE-cadherin (green) and anti-CD31 (red) of cells derived from mES cells (G&H) and miPS cells (I&J). DAPI, nucleus (blue). Magnifications are as indicated; the scale bar is 200 µm. Experiments were repeated 3 times. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0085549), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse VE-Cadherin by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse VE-Cadherin by Immunocytochemistry/Immunofluorescence FACS analysis of emerging vascular EC progenies from mES and iPS cells.Adherent cells (2x105) were detached and subjected to two-step FACS-aided purification. Control FACS profile on day 5 of cells derived from mES (J1) cells (A). Representative FACS profiles of day 5, with vascular progenies assessed using anti-Flk1 and anti-VE-cadherin antibodies obtained from mES (J1) cells (B) and derived from miPS (iMZ-21) cells (C); Control FACS profile on day 5 of cells derived from miPS (iMZ-21) cells (D). Representative FACS after the second step of purification derived from mES (E) and iPS cells (F). The yield of Flk1+VE-cadherin+ after the second round of FACS was 100% for both mES and miPS-derived vascular progenies. Morphology of mES- and miPS-derived vascular ECs (G-J). Flk1+VE-cadherin+ vascular progenies derived from mES and miPS cells were cultured overnight in IV Col-coated dishes, immunostained with anti-VE-cadherin (green) and anti-CD31 (red) of cells derived from mES cells (G&H) and miPS cells (I&J). DAPI, nucleus (blue). Magnifications are as indicated; the scale bar is 200 µm. Experiments were repeated 3 times. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0085549), licensed under a CC-BY license. Not internally tested by R&D Systems.

Flow Cytometry Detection of Mouse VE-Cadherin by Flow Cytometry View Larger

Detection of Mouse VE-Cadherin by Flow Cytometry FACS analysis of emerging vascular EC progenies from mES and iPS cells.Adherent cells (2x105) were detached and subjected to two-step FACS-aided purification. Control FACS profile on day 5 of cells derived from mES (J1) cells (A). Representative FACS profiles of day 5, with vascular progenies assessed using anti-Flk1 and anti-VE-cadherin antibodies obtained from mES (J1) cells (B) and derived from miPS (iMZ-21) cells (C); Control FACS profile on day 5 of cells derived from miPS (iMZ-21) cells (D). Representative FACS after the second step of purification derived from mES (E) and iPS cells (F). The yield of Flk1+VE-cadherin+ after the second round of FACS was 100% for both mES and miPS-derived vascular progenies. Morphology of mES- and miPS-derived vascular ECs (G-J). Flk1+VE-cadherin+ vascular progenies derived from mES and miPS cells were cultured overnight in IV Col-coated dishes, immunostained with anti-VE-cadherin (green) and anti-CD31 (red) of cells derived from mES cells (G&H) and miPS cells (I&J). DAPI, nucleus (blue). Magnifications are as indicated; the scale bar is 200 µm. Experiments were repeated 3 times. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0085549), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunohistochemistry Detection of Rat VE-Cadherin by Immunohistochemistry View Larger

Detection of Rat VE-Cadherin by Immunohistochemistry Chronic intermittent hypoxia modifies the BM vascular structure. a’–e’ Representative images of femur bone marrow stained with vWF, CD105, VE-cadherin, SMA, and CD11b counterstained with hematoxylin. a”, c”, d” BM from CIH exposed rats (n = 6) has more VE-cadherin+ vessels and SMA coverage but less vWF+ sinusoids (400×, Leica DM2500). e’, e” Representative images of CD11b immunohistochemistry in femur BM show an increase in BM monocyte count in CIH exposed animals. (400×, Leica DM2500) a’, a”’, b’, b” No changes in the total number of vessels or in megakaryocyte count were observed, as accounted by CD105 and vWF staining, respectively. Results are represented as the mean ± SD of bone marrow sections from six male Wistar rats (*p < 0.05; **p < 0.01). f Representative images of femur bone marrow fluorescently immunostained for VE-cadherin show an increase in total VE-cadherin vessels and in VE-cadherin vessel coverage. Scale bar, 50 μm (insets magnified 2.5×). Images were acquired with a Zeiss LSM 510 META microscope Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/26856724), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse VE-Cadherin by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse VE-Cadherin by Immunocytochemistry/Immunofluorescence Resting skin vessels contain high density HS moieties preferentially expressed at their basolateral compartments.(A, C, E, F, G) Axial and longitudinal sections of vessels of (A, B) naïve frozen, or (C, D, E, F, G) paraffin embedded murine flank skin tissues. Tissues were stained for HS with monoclonal mouse IgM (10E4 epitope; red), goat anti mouse VE-cadherin (cyan), FITC-mouse monoclonal to alpha -SMA (green), and nuclei (blue). (H) HS and alpha -SMA profile of the fluorescence intensity along the purple arrow in the merged image. Double-headed black arrow denotes the vessel lumen as indicated by VE-cadherin. In C, D and G, small-headed arrows denote the endothelial apical side, large-headed arrows denote the endothelial basolateral side, and broken-line arrows denote the pericyte basolateral side. Images were taken at 100X magnification. Scale bar represents 5 µm. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0085699), licensed under a CC-BY license. Not internally tested by R&D Systems.

Flow Cytometry Detection of Mouse VE-Cadherin by Flow Cytometry View Larger

Detection of Mouse VE-Cadherin by Flow Cytometry FACS analysis of emerging vascular EC progenies from mES and iPS cells.Adherent cells (2x105) were detached and subjected to two-step FACS-aided purification. Control FACS profile on day 5 of cells derived from mES (J1) cells (A). Representative FACS profiles of day 5, with vascular progenies assessed using anti-Flk1 and anti-VE-cadherin antibodies obtained from mES (J1) cells (B) and derived from miPS (iMZ-21) cells (C); Control FACS profile on day 5 of cells derived from miPS (iMZ-21) cells (D). Representative FACS after the second step of purification derived from mES (E) and iPS cells (F). The yield of Flk1+VE-cadherin+ after the second round of FACS was 100% for both mES and miPS-derived vascular progenies. Morphology of mES- and miPS-derived vascular ECs (G-J). Flk1+VE-cadherin+ vascular progenies derived from mES and miPS cells were cultured overnight in IV Col-coated dishes, immunostained with anti-VE-cadherin (green) and anti-CD31 (red) of cells derived from mES cells (G&H) and miPS cells (I&J). DAPI, nucleus (blue). Magnifications are as indicated; the scale bar is 200 µm. Experiments were repeated 3 times. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0085549), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse VE-Cadherin by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse VE-Cadherin by Immunocytochemistry/Immunofluorescence FACS analysis of emerging vascular EC progenies from mES and iPS cells.Adherent cells (2x105) were detached and subjected to two-step FACS-aided purification. Control FACS profile on day 5 of cells derived from mES (J1) cells (A). Representative FACS profiles of day 5, with vascular progenies assessed using anti-Flk1 and anti-VE-cadherin antibodies obtained from mES (J1) cells (B) and derived from miPS (iMZ-21) cells (C); Control FACS profile on day 5 of cells derived from miPS (iMZ-21) cells (D). Representative FACS after the second step of purification derived from mES (E) and iPS cells (F). The yield of Flk1+VE-cadherin+ after the second round of FACS was 100% for both mES and miPS-derived vascular progenies. Morphology of mES- and miPS-derived vascular ECs (G-J). Flk1+VE-cadherin+ vascular progenies derived from mES and miPS cells were cultured overnight in IV Col-coated dishes, immunostained with anti-VE-cadherin (green) and anti-CD31 (red) of cells derived from mES cells (G&H) and miPS cells (I&J). DAPI, nucleus (blue). Magnifications are as indicated; the scale bar is 200 µm. Experiments were repeated 3 times. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0085549), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse VE-Cadherin by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse VE-Cadherin by Immunocytochemistry/Immunofluorescence Resting skin vessels contain high density HS moieties preferentially expressed at their basolateral compartments.(A, C, E, F, G) Axial and longitudinal sections of vessels of (A, B) naïve frozen, or (C, D, E, F, G) paraffin embedded murine flank skin tissues. Tissues were stained for HS with monoclonal mouse IgM (10E4 epitope; red), goat anti mouse VE-cadherin (cyan), FITC-mouse monoclonal to alpha -SMA (green), and nuclei (blue). (H) HS and alpha -SMA profile of the fluorescence intensity along the purple arrow in the merged image. Double-headed black arrow denotes the vessel lumen as indicated by VE-cadherin. In C, D and G, small-headed arrows denote the endothelial apical side, large-headed arrows denote the endothelial basolateral side, and broken-line arrows denote the pericyte basolateral side. Images were taken at 100X magnification. Scale bar represents 5 µm. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0085699), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse VE-Cadherin by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse VE-Cadherin by Immunocytochemistry/Immunofluorescence FACS analysis of emerging vascular EC progenies from mES and iPS cells.Adherent cells (2x105) were detached and subjected to two-step FACS-aided purification. Control FACS profile on day 5 of cells derived from mES (J1) cells (A). Representative FACS profiles of day 5, with vascular progenies assessed using anti-Flk1 and anti-VE-cadherin antibodies obtained from mES (J1) cells (B) and derived from miPS (iMZ-21) cells (C); Control FACS profile on day 5 of cells derived from miPS (iMZ-21) cells (D). Representative FACS after the second step of purification derived from mES (E) and iPS cells (F). The yield of Flk1+VE-cadherin+ after the second round of FACS was 100% for both mES and miPS-derived vascular progenies. Morphology of mES- and miPS-derived vascular ECs (G-J). Flk1+VE-cadherin+ vascular progenies derived from mES and miPS cells were cultured overnight in IV Col-coated dishes, immunostained with anti-VE-cadherin (green) and anti-CD31 (red) of cells derived from mES cells (G&H) and miPS cells (I&J). DAPI, nucleus (blue). Magnifications are as indicated; the scale bar is 200 µm. Experiments were repeated 3 times. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0085549), licensed under a CC-BY license. Not internally tested by R&D Systems.

In-situ Hybridization View Larger

Detection of VE‑Cadherin in Mouse Heart. Formalin-fixed paraffin-embedded tissue sections of mouse heart were probed for VE-Cadherin mRNA (ACD RNAScope Probe, catalog #312538; Fast Red chromogen, ACD catalog # 322750). Adjacent tissue section was processed for immunohistochemistry using goat anti-mouse VE-Cadherin polyclonal antibody (R&D Systems catalog # AF1002) at 3ug/mL with 1 hour incubation at room temperature followed by incubation with anti-goat IgG VisUCyte HRP Polymer Antibody (Catalog # VC004) and DAB chromogen (yellow-brown). Tissue was counterstained with hematoxylin (blue). Specific staining was localized to cardiac myocytes.

Western Blot Detection of Mouse Mouse VE-Cadherin Antibody by Western Blot View Larger

Detection of Mouse Mouse VE-Cadherin Antibody by Western Blot Warfarin pretreatment enhances tumor Ad5ROBO4 vector expression.A. Multiorgan immunoblot of vehicle (left lanes) or warfarin (right lanes) pretreated Rag2−/− mice injected with 1.0×1011 vp of Ad5ROBO4. B. Densitometry of A revealed that vehicle pretreatment was associated with robust liver, detectable splenic, and trace to undetectable expression in all other sampled organs. Warfarin pretreatment produced a 2.5-fold increased splenic and a 3-fold decreased liver expression while all other organs still evidenced trace to undetectable expression. C. Immunoblot and densitometry of liver and tumor EGFP, VE-cadherin, and beta -tubulin expression in vehicle (left lanes) or warfarin (right lanes) from the same pretreated, Ad5ROBO4-injected mice as in A and B. EGFP densitometry normalized to VE-cadherin, revealed a 4.7-fold decrease in liver and 2-fold increase in increase KO and SC tumor expression produced by warfarin pretreatment. A–C: representative immunoblots from n = 2 mice from 2 independent experiments. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/24376772), licensed under a CC-BY license. Not internally tested by R&D Systems.

Western Blot Detection of Mouse Mouse VE-Cadherin Antibody by Western Blot View Larger

Detection of Mouse Mouse VE-Cadherin Antibody by Western Blot Semiquantitative immunoblotting reveals differential Ad5ROBO4 reporter expression in tumor compared to liver.A. Immunoblot of EGFP, VE-cadherin, and beta -tubulin loading controls in tissue protein extracts from hCAR:Rag2−/− mice injected with either Ad5ROBO4, left three lanes, or Ad5CMV, right three lanes. B. and C. Densitometry analysis of Ad5ROBO4 vector EGFP expression normalized to either VE-cadherin or beta -tubulin. D. Densitometry of AdCMV vector EGFP expression. As AdCMV expression was hepatocyte specific, this blot was only normalized to beta -tubulin. A–D: Representative immunoblots from n = 4 mice injected with either Ad5ROBO 4 or Ad5CMV vectors. Li: liver, KO: kidney orthotopic tumor, SC: subcutaneous tumor. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/24376772), licensed under a CC-BY license. Not internally tested by R&D Systems.

Western Blot Detection of Mouse Mouse VE-Cadherin Antibody by Western Blot View Larger

Detection of Mouse Mouse VE-Cadherin Antibody by Western Blot Endogenous ROBO4 upregulation despite lower vascular density in orthotopic and xenograft tumors.A. Immunofluorescence of the vascular endothelium in liver (upper panel) and 786-O human renal cell carcinoma (RCC) subcutaneous xenograft tumor (lower panel). B. Vascular area analysis of liver (Li), kidney orthotopic (KO) tumors, and subcutaneous (SC) xenograft tumors (n = 6 mice analyzed). C. Immunoblot of endogenous ROBO4 and the endothelial cell specific VE-cadherin from liver, kidney orthotopic and subcutaneous xenograft 786-O RCC tumors, and from the derivative 786-O cells grown in culture. D. Densitometry analysis of VE-cadherin/tubulin ratio from C mirrors the vascular area determination in B. E. Densitometry analysis of endogenous ROBO4 normalized to VE-cadherin expression reveals a 1.4- to 2-fold increase in SC and KO tumors compared to liver. C–E: Immunoblot and densitometry was repeated twice with two independent sets of protein extracts from two different tumor-bearing mice with essentially the same results. A. Magnification: 100X, Red: endomucin/CD31 antibody cocktail, Blue: DAPI. B. *p<0.05, one way ANOVA with Tukey's correction, mean ± SD. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/24376772), licensed under a CC-BY license. Not internally tested by R&D Systems.

Western Blot Detection of Mouse Mouse VE-Cadherin Antibody by Western Blot View Larger

Detection of Mouse Mouse VE-Cadherin Antibody by Western Blot Warfarin pretreatment enhances tumor Ad5ROBO4 vector expression.A. Multiorgan immunoblot of vehicle (left lanes) or warfarin (right lanes) pretreated Rag2−/− mice injected with 1.0×1011 vp of Ad5ROBO4. B. Densitometry of A revealed that vehicle pretreatment was associated with robust liver, detectable splenic, and trace to undetectable expression in all other sampled organs. Warfarin pretreatment produced a 2.5-fold increased splenic and a 3-fold decreased liver expression while all other organs still evidenced trace to undetectable expression. C. Immunoblot and densitometry of liver and tumor EGFP, VE-cadherin, and beta -tubulin expression in vehicle (left lanes) or warfarin (right lanes) from the same pretreated, Ad5ROBO4-injected mice as in A and B. EGFP densitometry normalized to VE-cadherin, revealed a 4.7-fold decrease in liver and 2-fold increase in increase KO and SC tumor expression produced by warfarin pretreatment. A–C: representative immunoblots from n = 2 mice from 2 independent experiments. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/24376772), licensed under a CC-BY license. Not internally tested by R&D Systems.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Loading...
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: VE-Cadherin

The cadherin (Ca++-dependent adherence) superfamily is a large group of membrane-associated glycoproteins that engage in homotypic, calcium-dependent, cell-cell adhesion events. The superfamily can be divided into at least five major subfamilies based on molecule gene structure, and/or extracellular (EC) and intracellular domains (1-4). Subfamilies include classical/type I, atypical/type II, and desmosomal-related cadherins (1-3). VE-Cadherin (vascular endothelial cadherin; also cadherin-5 and CD144) is a 125 kDa atypical/type II subfamily cadherin. Its subfamily classification is based principally on its genomic structure, as its physical structure is notably divergent from other type II subfamily members (2, 3). Mouse VE-Cadherin is synthesized as a 784 amino acid (aa) type I transmembrane (TM) preproprotein that contains a 24 aa signal peptide, a 21 aa prosequence, a 554 aa extracellular region (ECR), a 21 aa TM segment, and a 164 aa cytoplasmic domain (5, 6). The ECR contains five Ca++-binding cadherin domains that are approximately 105 aa in length. Cadherin domains are comprised of two beta ‑sheets that are oriented like bread in a sandwich. Although complex, the N-terminal cadherin domain mediates trans interactions, while the internal domains contribute to cis multimerizations (7). Mouse VE-Cadherin ECR is 92%, 77%, and 73% aa identical to rat, human and porcine VE-Cadherin ECR, respectively. VE-Cadherin is involved in the maintenance of endothelial permeability. In this regard, VE-Cadherin does not initiate new blood vessel formation; it maintains it once formed. Thus, when VE‑Cadherin is downregulated, cells part and permeability increases (8). Notably, VEGF is known to promote vascular leakage, and apparently does so by inducing a beta ‑arrestin-dependent endocytosis of VE-Cadherin (9). Part of this effect may be mediated by VE‑Cadherin itself which is reported to increase the membrane half-life of VEGF R2 (10). VE-Cadherin acts homotypically at sites of zonula adherens. On each expressing cell, it is proposed that VE-Cadherin first forms a trimer, which then dimerizes with a trimeric counterpart in-trans. Alternatively, two cis-dimers could act in-trans to generate homotypic binding (11). In addition to cell adhesion, VE‑Cadherin also is reported to mediate TGF-beta receptor assembly. When clustered, VE‑Cadherin enhances T beta RII/T beta RI assembly into an active receptor complex on endothelial cells (12). VE-Cadherin is expressed on endothelial cells, trophoblast cells, endothelial progenitor cells and embryonic hematopoietic cells (5, 8, 13, 14).

References
  1. Patel, S.D. et al. (2007) Curr. Opin. Struct. Biol. 13:690.
  2. Vestweber, D. (2008) Arterioscler. Thromb. Vasc. Biol. 28:223.
  3. Vincent, P.A. et al. (2004) Am. J. Physiol. Cell. Physiol. 286:C987.
  4. Cavallaro, U. et al. (2006) Exp. Cell Res. 312:659.
  5. Breier, G. et al. (1996) Blood 87:630.
  6. Huber, P. et al. (1996) Genomics 32:21.
  7. Pokutta, S. and W.I. Weis (2007) Annu. Rev. Cell Dev. Biol. 23:237.
  8. Crosby, C.V. et al. (2005) Blood 105:2771.
  9. Gavard, J. and J.S. Gutkind (2006) Nat. Cell Biol. 8:1223.
  10. Calera, M.R. et al. (2004) Exp. Cell Res. 300:248.
  11. Hewat, E.A. et al. (2007) J. Mol. Biol. 365:744.
  12. Rudini, N. et al. (2008) EMBO J. 27:993.
  13. Kogata, N. et al. (2006) Circ. Res. 98:897.
  14. Ema, M. et al. (2006) Blood 108:4018.
Long Name
Vascular Endothelium Cadherin
Entrez Gene IDs
1003 (Human); 12562 (Mouse)
Alternate Names
7B4 antigen; 7B4; cadherin 5, type 2 (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular epithelium); Cadherin-5; CD144 antigen; CD144; CDH5; endothelial-specific cadherin; FLJ17376; Vascular endothelial cadherin; VECadherin; VE-Cadherin

Product Datasheets

You must select a language.

x
Product Datasheet
COA
SDS

Citations for Mouse VE-Cadherin Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

118 Citations: Showing 1 - 10
Filter your results:

Filter by:

  1. Annexin A2 supports pulmonary microvascular integrity by linking vascular endothelial cadherin and protein tyrosine phosphatases
    Authors: Luo M, Flood EC, Almeida D et al.
    J. Exp. Med.
  2. Foxc1 and Foxc2 deletion causes abnormal lymphangiogenesis and correlates with ERK hyperactivation
    J Clin Invest, 2016-05-23;0(0):.
  3. Sphingosine 1-Phosphate Receptor Signaling Establishes AP-1 Gradients to Allow for Retinal Endothelial Cell Specialization
    Authors: Yanagida K, Engelbrecht E, Niaudet C et al.
    Dev. Cell
  4. Apelin modulates inflammation and leukocyte recruitment in experimental autoimmune encephalomyelitis
    Authors: Park, H;Song, J;Jeong, HW;Grönloh, MLB;Koh, BI;Bovay, E;Kim, KP;Klotz, L;Thistlethwaite, PA;van Buul, JD;Sorokin, L;Adams, RH;
    Nature communications
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  5. ?1 integrins play a critical role maintaining vascular integrity in the hypoxic spinal cord, particularly in white matter
    Authors: Halder, SK;Sapkota, A;Milner, R;
    Acta neuropathologica communications
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  6. An EPHB4-RASA1 signaling complex inhibits shear stress-induced Ras-MAPK activation in lymphatic endothelial cells to promote the development of lymphatic vessel valves
    Authors: Chen, D;Wiggins, D;Sevick, EM;Davis, MJ;King, PD;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  7. Identification of CD133+ intercellsomes in intercellular communication to offset intracellular signal deficit
    Authors: Kaneko, K;Liang, Y;Liu, Q;Zhang, S;Scheiter, A;Song, D;Feng, GS;
    eLife
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  8. Spatial-temporal proliferation of hepatocytes during pregnancy revealed by genetic lineage tracing
    Authors: He, S;Guo, Z;Zhou, M;Wang, H;Zhang, Z;Shi, M;Li, X;Yang, X;He, L;
    Cell stem cell
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  9. Alk1 acts in non-endothelial VE-cadherin+ perineurial cells to maintain nerve branching during hair homeostasis
    Authors: Chovatiya, G;Li, KN;Li, J;Ghuwalewala, S;Tumbar, T;
    Nature communications
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  10. FYN regulates aqueous humor outflow and IOP through the phosphorylation of VE-cadherin
    Authors: Kizhatil, K;Clark, G;Sunderland, D;Bhandari, A;Horbal, L;Balasubramanian, R;John, S;
    bioRxiv : the preprint server for biology
    Species: Transgenic Mouse
    Sample Types: Tissue Homogenates, Whole Tissue
    Applications: IHC, Western Blot
  11. Temporal Progression of Aortic Valve Pathogenesis in a Mouse Model of Osteogenesis Imperfecta
    Authors: Thatcher, K;Mattern, CR;Chaparro, D;Goveas, V;McDermott, MR;Fulton, J;Hutcheson, JD;Hoffmann, BR;Lincoln, J;
    Journal of cardiovascular development and disease
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  12. Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation
    Authors: Zhang, T;Xu, D;Liu, J;Wang, M;Duan, LJ;Liu, M;Meng, H;Zhuang, Y;Wang, H;Wang, Y;Lv, M;Zhang, Z;Hu, J;Shi, L;Guo, R;Xie, X;Liu, H;Erickson, E;Wang, Y;Yu, W;Dang, F;Guan, D;Jiang, C;Dai, X;Inuzuka, H;Yan, P;Wang, J;Babuta, M;Lian, G;Tu, Z;Miao, J;Szabo, G;Fong, GH;Karnoub, AE;Lee, YR;Pan, L;Kaelin, WG;Yuan, J;Wei, W;
    Nature cell biology
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  13. Partial Mural Cell Ablation Disrupts Coronary Vasculature Integrity and Induces Systolic Dysfunction
    Authors: Cornuault, L;Hérion, FX;Bourguignon, C;Rouault, P;Foussard, N;Alzieu, P;Chapouly, C;Gadeau, AP;Couffinhal, T;Renault, MA;
    Journal of the American Heart Association
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  14. Cytarabine induces cachexia with lipid malabsorption via zippering the junctions of lacteal in murine small intestine
    Authors: Mi-Rae Park, Hye-Jin Lee, Hye-Min Jang, Nam Hoon Kim, Jun-Seok Lee, Yong Taek Jeong et al.
    Journal of Lipid Research
  15. EZH2 controls epicardial cell migration during heart development
    Authors: Jiang H, Bai L, Song S et al.
    Life science alliance
  16. Therapeutic activation of endothelial sphingosine‐1‐phosphate receptor 1 by chaperone‐bound S1P suppresses proliferative retinal neovascularization
    Authors: Colin Niaudet, Bongnam Jung, Andrew Kuo, Steven Swendeman, Edward Bull, Takahiro Seno et al.
    EMBO Molecular Medicine
  17. Osteoprogenitor-GMP crosstalk underpins solid tumor-induced systemic immunosuppression and persists after tumor removal
    Authors: Hao, X;Shen, Y;Chen, N;Zhang, W;Valverde, E;Wu, L;Chan, HL;Xu, Z;Yu, L;Gao, Y;Bado, I;Michie, LN;Rivas, CH;Dominguez, LB;Aguirre, S;Pingel, BC;Wu, YH;Liu, F;Ding, Y;Edwards, DG;Liu, J;Alexander, A;Ueno, NT;Hsueh, PR;Tu, CY;Liu, LC;Chen, SH;Hung, MC;Lim, B;Zhang, XH;
    Cell stem cell
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  18. Endothelial deletion of PTBP1 disrupts ventricular chamber development
    Authors: H Liu, R Duan, X He, J Qi, T Xing, Y Wu, L Zhou, L Wang, Y Shao, F Zhang, H Zhou, X Gu, B Lin, Y Liu, Y Wang, Y Liu, L Li, D Liang, YH Chen
    Nature Communications, 2023-03-31;14(1):1796.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  19. Trans-differentiation of trophoblast stem cells: implications in placental biology
    Authors: Madhurima Paul, Shreeta Chakraborty, Safirul Islam, Rupasri Ain
    Life Science Alliance
  20. IFNgamma blockade in capillary leak site improves tumour chemotherapy by inhibiting lactate-induced endocytosis of vascular endothelial-cadherins
    Authors: R Wang, C Ni, X Lou, L Zhang, L Wang, X Yao, X Duan, J Wan, P Li, Z Qin
    International journal of biological sciences, 2023-02-27;19(5):1490-1508.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC, Western Blot, ICC
  21. An agonistic anti-Tie2 antibody suppresses the normal-to-tumor vascular transition in the glioblastoma invasion zone
    Authors: E Lee, EA Lee, E Kong, H Chon, M Llaiqui-Co, CH Park, BY Park, NR Kang, JS Yoo, HS Lee, HS Kim, SH Park, SW Choi, D Vestweber, JH Lee, P Kim, WS Lee, I Kim
    Experimental & Molecular Medicine, 2023-02-24;55(2):470-484.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  22. Bone metastasis initiation is coupled with bone remodeling through osteogenic differentiation of NG2+ cells
    Authors: W Zhang, Z Xu, X Hao, T He, J Li, Y Shen, K Liu, Y Gao, J Liu, D Edwards, AM Muscarella, L Wu, L Yu, L Xu, X Chen, YH Wu, IL Bado, Y Ding, S Aguirre, H Wang, Z Gugala, RL Satcher, ST Wong, XH Zhang
    Cancer Discovery, 2023-02-06;0(0):.
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  23. Shear stress control of vascular leaks and atheromas through Tie2 activation by VE-PTP sequestration
    Authors: K Shirakura, P Baluk, AF Nottebaum, U Ipe, KG Peters, DM McDonald, D Vestweber
    Embo Molecular Medicine, 2023-02-06;0(0):e16128.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  24. A Prox1 enhancer represses haematopoiesis in the lymphatic vasculature
    Authors: J Kazenwadel, P Venugopal, A Oszmiana, J Toubia, L Arriola-Ma, V Panara, SG Piltz, C Brown, W Ma, AW Schreiber, K Koltowska, S Taoudi, PQ Thomas, HS Scott, NL Harvey
    Nature, 2023-01-25;614(7947):343-348.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  25. Deficiency of endothelial FGFR1 alleviates hyperoxia-induced bronchopulmonary dysplasia in neonatal mice
    Authors: Yanrong Long, Hongbin Chen, Junchao Deng, Junjie Ning, Pengbo Yang, Lina Qiao et al.
    Frontiers in Pharmacology
  26. Phosphorylcholine Monoclonal Antibody Therapy Decreases Intraplaque Angiogenesis and Intraplaque Hemorrhage in Murine Vein Grafts
    Authors: F Baganha, TJ Sluiter, RCM de Jong, LA van Alst, HAB Peters, JW Jukema, M Delibegovi, K Pettersson, PHA Quax, MR de Vries
    International Journal of Molecular Sciences, 2022-11-07;23(21):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  27. MASP-2 and MASP-3 inhibitors block complement activation, inflammation, and microvascular stasis in a murine model of vaso-occlusion in sickle cell disease
    Authors: John D. Belcher, Julia Nguyen, Chunsheng Chen, Fuad Abdulla, Ruan Conglin, Zalaya K. Ivy et al.
    Translational Research
  28. Endothelial deletion of TBK1 contributes to BRB dysfunction via CXCR4 phosphorylation suppression
    Authors: Bowen Zhao, Yueqi Ni, Hong Zhang, Yin Zhao, Lu Li
    Cell Death Discovery
  29. Syndecan-2 selectively regulates VEGF-induced vascular permeability
    Authors: F. Corti, E. Ristori, F. Rivera-Molina, D. Toomre, J. Zhang, J. Mihailovic et al.
    Nature Cardiovascular Research
  30. p73 is required for vessel integrity controlling endothelial junctional dynamics through Angiomotin
    Authors: Laura Maeso-Alonso, Hugo Alonso-Olivares, Nicole Martínez-García, Lorena López-Ferreras, Javier Villoch-Fernández, Laura Puente-Santamaría et al.
    Cellular and Molecular Life Sciences
  31. SARS-CoV-2 disrupts respiratory vascular barriers by suppressing Claudin-5 expression
    Authors: R Hashimoto, J Takahashi, K Shirakura, R Funatsu, K Kosugi, S Deguchi, M Yamamoto, Y Tsunoda, M Morita, K Muraoka, M Tanaka, T Kanbara, S Tanaka, S Tamiya, N Tokunoh, A Kawai, M Ikawa, C Ono, K Tachibana, M Kondoh, M Obana, Y Matsuura, A Ohsumi, T Noda, T Yamamoto, Y Yoshioka, YS Torisawa, H Date, Y Fujio, M Nagao, K Takayama, Y Okada
    Science Advances, 2022-09-21;8(38):eabo6783.
    Species: Human, Mouse
    Sample Types: Cell Lysates, Tissue Homogenates
    Applications: Western Blot
  32. Network pharmacology and experimental analysis to reveal the mechanism of Dan-Shen-Yin against endothelial to mesenchymal transition in atherosclerosis
    Authors: Mengyun Hong, Yubiao Wu, Haiyi Zhang, Jinchao Gu, Juanjuan Chen, Yancheng Guan et al.
    Frontiers in Pharmacology
  33. Identification and implication of tissue-enriched ligands in epithelial-endothelial crosstalk during pancreas development
    Authors: M Moulis, SVM Runser, L Glorieux, N Dauguet, C Vanderaa, L Gatto, D Tyteca, P Henriet, FM Spagnoli, D Iber, CE Pierreux
    Scientific Reports, 2022-07-21;12(1):12498.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  34. Claudin5 protects the peripheral endothelial barrier in an organ and vessel-type-specific manner
    Authors: Mark Richards, Emmanuel Nwadozi, Sagnik Pal, Pernilla Martinsson, Mika Kaakinen, Marleen Gloger et al.
    eLife
  35. Caspase-8 in endothelial cells maintains gut homeostasis and prevents small bowel inflammation in mice
    Authors: N Tisch, C Mogler, A Stojanovic, R Luck, EA Korhonen, A Ellerkmann, H Adler, M Singhal, G Schermann, L Erkert, JV Patankar, A Karakatsan, AL Scherr, Y Fuchs, A Cerwenka, S Wirtz, BC Köhler, HG Augustin, C Becker, T Schmidt, C Ruiz de Al
    Embo Molecular Medicine, 2022-05-02;0(0):e14121.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  36. Structural and Functional Changes in Aged Skin Lymphatic Vessels
    Authors: Raghu P. Kataru, Hyeung Ju Park, Jinyeon Shin, Jung Eun Baik, Ananta Sarker, Stav Brown et al.
    Frontiers in Aging
  37. The amyloid peptide beta disrupts intercellular junctions and increases endothelial permeability in a NADPH oxidase 1-dependent manner
    Authors: A Tarafdar, N Wolska, C Krisp, H Schlüter, G Pula
    Redox Biology, 2022-03-25;52(0):102287.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC/IF
  38. Engineering a niche supporting hematopoietic stem cell development using integrated single-cell transcriptomics
    Authors: Brandon Hadland, Barbara Varnum-Finney, Stacey Dozono, Tessa Dignum, Cynthia Nourigat-McKay, Adam M. Heck et al.
    Nature Communications
  39. Force-induced changes of alpha-catenin conformation stabilize vascular junctions independent of vinculin
    Authors: CN Duong, R Brückner, M Schmitt, AF Nottebaum, L Braun, MM Zu Brickwe, U Ipe, H Vom Bruch, HR Schöler, G Trapani, B Trappmann, MP Ebrahimkut, S Huveneers, J Rooij, N Ishiyama, M Ikura, D Vestweber
    Journal of Cell Science, 2021-12-22;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  40. Tgf?1-Cthrc1 Signaling Plays an Important Role in the Short-Term Reparative Response to Heart Valve Endothelial Injury
    Authors: Nordquist EM, Dutta P, Kodigepalli KM et al.
    Arteriosclerosis, Thrombosis, and Vascular Biology
  41. Low-flow intussusception and metastable VEGFR2 signaling launch angiogenesis in ischemic muscle
    Authors: JM Arpino, H Yin, EK Prescott, SCR Staples, Z Nong, F Li, J Chevalier, B Balint, C O'Neil, R Mortuza, S Milkovich, JJ Lee, D Lorusso, M Sandig, DW Hamilton, DW Holdsworth, TL Poepping, CG Ellis, JG Pickering
    Science Advances, 2021-11-26;7(48):eabg9509.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  42. Lef1 restricts ectopic crypt formation and tumor cell growth in intestinal adenomas
    Authors: S Heino, S Fang, M Lähde, J Högström, S Nassiri, A Campbell, D Flanagan, A Raven, M Hodder, N Nasreddin, HH Xue, M Delorenzi, S Leedham, TV Petrova, O Sansom, K Alitalo
    Science Advances, 2021-11-17;7(47):eabj0512.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  43. Full-length Dhh and N-terminal Shh act as competitive antagonists to regulate angiogenesis and vascular permeability
    Authors: Pierre-Louis Hollier, Candice Chapouly, Aissata Diop, Sarah Guimbal, Lauriane Cornuault, Alain-Pierre Gadeau et al.
    Cardiovascular Research
  44. Imbalanced Activation of Wnt-/ beta -Catenin-Signaling in Liver Endothelium Alters Normal Sinusoidal Differentiation
    Authors: Philipp-Sebastian Koch, Kajetan Sandorski, Joschka Heil, Christian D. Schmid, Sina W. Kürschner, Johannes Hoffmann et al.
    Frontiers in Physiology
  45. Fetal hematopoietic stem cell homing is controlled by VEGF regulating the integrity and oxidative status of the stromal-vascular bone marrow niches
    Authors: M Mesnieres, AM Böhm, N Peredo, D Trompet, R Valle-Tenn, M Bajaj, N Corthout, E Nefyodova, R Cardoen, P Baatsen, S Munck, A Nagy, JJ Haigh, S Khurana, CM Verfaillie, C Maes
    Cell Reports, 2021-08-24;36(8):109618.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  46. Lymphatic-specific intracellular modulation of receptor tyrosine kinase signaling improves lymphatic growth and function
    Authors: Raghu P. Kataru, Jung Eun Baik, Hyeung Ju Park, Catherine L. Ly, Jinyeon Shin, Noa Schwartz et al.
    Science Signaling
  47. Atorvastatin pleiotropically decreases intraplaque angiogenesis and intraplaque haemorrhage by inhibiting ANGPT2 release and VE-Cadherin internalization
    Authors: Fabiana Baganha, Rob C. M. de Jong, Erna A. Peters, Wietske Voorham, J. Wouter Jukema, Mirela Delibegovic et al.
    Angiogenesis
  48. Aminophylline modulates the permeability of endothelial cells via the Slit2‑Robo4 pathway in lipopolysaccharide‑induced inflammation
    Authors: Qin Chen, Xiaoming Zhou, Ruonan Hou, Zhiliang Zhou, Zhiyi Wang, Ying Chen et al.
    Experimental and Therapeutic Medicine
  49. Protease nexin-1 deficiency increases mouse hindlimb neovascularisation following ischemia and accelerates femoral artery perfusion
    Authors: S Selbonne, C Madjene, B Salmon, Y Boulaftali, MC Bouton, V Arocas
    Scientific Reports, 2021-06-28;11(1):13412.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  50. Intra-vessel heterogeneity establishes enhanced sites of macromolecular leakage downstream of laminin &alpha5
    Authors: M Richards, S Pal, E Sjöberg, P Martinsson, L Venkatrama, L Claesson-W
    Cell Reports, 2021-06-22;35(12):109268.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  51. eNOS-induced vascular barrier disruption in retinopathy by c-Src activation and tyrosine phosphorylation of VE-cadherin
    Authors: Takeshi Ninchoji, Dominic T Love, Ross O Smith, Marie Hedlund, Dietmar Vestweber, William C Sessa et al.
    eLife
  52. The bone microenvironment invigorates metastatic seeds for further dissemination
    Authors: Weijie Zhang, Igor L. Bado, Jingyuan Hu, Ying-Wooi Wan, Ling Wu, Hai Wang et al.
    Cell
  53. Paladin is a phosphoinositide phosphatase regulating endosomal VEGFR2 signalling and angiogenesis
    Authors: Anja Nitzsche, Riikka Pietilä, Dominic T Love, Chiara Testini, Takeshi Ninchoji, Ross O Smith et al.
    EMBO reports
  54. CD112 Regulates Angiogenesis and T Cell Entry into the Spleen
    Authors: E Russo, P Runge, NH Jahromi, H Naboth, A Landtwing, R Montecchi, N Leicht, MC Hunter, Y Takai, C Halin
    Cells, 2021-01-15;10(1):.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  55. Endothelial C3a receptor mediates vascular inflammation and blood-brain barrier permeability during aging
    Authors: Nicholas E. Propson, Ethan R. Roy, Alexandra Litvinchuk, Jörg Köhl, Hui Zheng
    Journal of Clinical Investigation
  56. A Type 2 Deiodinase-Dependent Increase in Vegfa Mediates Myoblast-Endothelial Cell Crosstalk During Skeletal Muscle Regeneration
    Authors: Xingxing An, Ashley Ogawa-Wong, Colleen Carmody, Raffaele Ambrosio, Annunziata Gaetana Cicatiello, Cristina Luongo et al.
    Thyroid
  57. Desert Hedgehog-Driven Endothelium Integrity Is Enhanced by Gas1 (Growth Arrest-Specific 1) but Negatively Regulated by Cdon (Cell Adhesion Molecule-Related/Downregulated by Oncogenes)
    Authors: Candice Chapouly, Pierre-Louis Hollier, Sarah Guimbal, Lauriane Cornuault, Alain-Pierre Gadeau, Marie-Ange Renault
    Arteriosclerosis, Thrombosis, and Vascular Biology
  58. Regeneration of the pulmonary vascular endothelium after viral pneumonia requires COUP-TF2
    Authors: Gan Zhao, Aaron I. Weiner, Katherine M. Neupauer, Maria Fernanda de Mello Costa, Gargi Palashikar, Stephanie Adams-Tzivelekidis et al.
    Science Advances
  59. Deficiency of peroxiredoxin 2 exacerbates angiotensin II-induced abdominal aortic aneurysm
    Authors: SJ Jeong, MJ Cho, NY Ko, S Kim, IH Jung, JK Min, SH Lee, JG Park, GT Oh
    Exp. Mol. Med., 2020-09-14;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  60. Simulating flow induced migration in vascular remodelling
    Authors: A Tabibian, S Ghaffari, DA Vargas, H Van Ooster, EAV Jones
    PLoS Comput. Biol., 2020-08-21;16(8):e1007874.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  61. Distinct fibroblast subsets regulate lacteal integrity through YAP/TAZ-induced VEGF-C in intestinal villi
    Authors: SP Hong, MJ Yang, H Cho, I Park, H Bae, K Choe, SH Suh, RH Adams, K Alitalo, D Lim, GY Koh
    Nat Commun, 2020-08-14;11(1):4102.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  62. An autophagic deficit in the uterine vessel microenvironment provokes hyperpermeability through deregulated VEGFA, NOS1, and CTNNB1
    Authors: B Lee, H Shin, JE Oh, J Park, M Park, SC Yang, JH Jun, SH Hong, H Song, HJ Lim
    Autophagy, 2020-06-17;0(0):1-18.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  63. Shear stimulation of FOXC1 and FOXC2 differentially regulates cytoskeletal activity during lymphatic valve maturation
    Authors: Pieter R Norden, Amélie Sabine, Ying Wang, Cansaran Saygili Demir, Ting Liu, Tatiana V Petrova et al.
    eLife
  64. Atypical cadherin Fat4 orchestrates lymphatic endothelial cell polarity in response to flow
    Authors: KL Betterman, DL Sutton, GA Secker, J Kazenwadel, A Oszmiana, L Lim, N Miura, L Sorokin, BM Hogan, ML Kahn, H McNeill, NL Harvey
    J. Clin. Invest., 2020-06-01;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  65. Canonical signaling by TGF family members in mesenchymal stromal cells is dispensable for hematopoietic niche maintenance under basal and stress conditions
    Authors: JR Krambs, G Abou Ezzi, JC Yao, DC Link
    PLoS ONE, 2020-05-29;15(5):e0233751.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  66. Using apelin-based synthetic Notch receptors to detect angiogenesis and treat solid tumors
    Authors: Z Wang, F Wang, J Zhong, T Zhu, Y Zheng, T Zhao, Q Xie, F Ma, R Li, Q Tang, F Xu, X Tian, J Zhu
    Nat Commun, 2020-05-01;11(1):2163.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  67. c-Src controls stability of sprouting blood vessels in the developing retina independently of cell-cell adhesion through focal adhesion assembly
    Authors: Lilian Schimmel, Daisuke Fukuhara, Mark Richards, Yi Jin, Patricia Essebier, Emmanuelle Frampton et al.
    Development
  68. Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta
    Authors: Eric Engelbrecht, Michel V Levesque, Liqun He, Michael Vanlandewijck, Anja Nitzsche, Hira Niazi et al.
    eLife
  69. Interference With ESAM (Endothelial Cell-Selective Adhesion Molecule) Plus Vascular Endothelial-Cadherin Causes Immediate Lethality and Lung-Specific Blood Coagulation
    Authors: Cao Nguyen Duong, Astrid F. Nottebaum, Stefan Butz, Stefan Volkery, Dagmar Zeuschner, Martin Stehling et al.
    Arteriosclerosis, Thrombosis, and Vascular Biology
  70. EphA2 contributes to disruption of the blood-brain barrier in cerebral malaria
    Authors: TK Darling, PN Mimche, C Bray, B Umaru, LM Brady, C Stone, CE Eboumbou M, TE Lane, LS Ayong, TJ Lamb
    PLoS Pathog., 2020-01-30;16(1):e1008261.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC
  71. Inhibition of Sema4D/PlexinB1 signaling alleviates vascular dysfunction in diabetic retinopathy
    Authors: JH Wu, YN Li, AQ Chen, CD Hong, CL Zhang, HL Wang, YF Zhou, PC Li, Y Wang, L Mao, YP Xia, QW He, HJ Jin, ZY Yue, B Hu
    EMBO Mol Med, 2020-01-13;12(2):e10154.
    Species: Mouse
    Sample Types: Protein
    Applications: Western Blot
  72. A genetic system for tissue-specific inhibition of cell proliferation
    Authors: Wenjuan Pu, Ximeng Han, Lingjuan He, Yan Li, Xiuzhen Huang, Mingjun Zhang et al.
    Development
  73. VEGF/VEGFR2 signaling regulates hippocampal axon branching during development
    Authors: Robert Luck, Severino Urban, Andromachi Karakatsani, Eva Harde, Sivakumar Sambandan, LaShae Nicholson et al.
    eLife
  74. Loss of flow responsive Tie1 results in Impaired Aortic valve remodeling
    Authors: Xianghu Qu, Kate Violette, M. K. Sewell-Loftin, Jonathan Soslow, LeShana Saint-Jean, Robert B. Hinton et al.
    Developmental Biology
  75. Dynamic Interplay between Pericytes and Endothelial Cells during Sprouting Angiogenesis
    Authors: G Chiaverina, L di Blasio, V Monica, M Accardo, M Palmiero, B Peracino, M Vara-Messl, A Puliafito, L Primo
    Cells, 2019-09-19;8(9):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  76. Bone marrow dendritic cells regulate hematopoietic stem/progenitor cell trafficking
    Authors: J Zhang, T Supakornde, JR Krambs, M Rao, G Abou-Ezzi, RY Ye, S Li, K Trinkaus, DC Link
    J. Clin. Invest., 2019-04-30;129(7):2920-2931.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  77. Lineage Tracing Reveals the Bipotency of SOX9+ Hepatocytes during Liver Regeneration
    Authors: X Han, Y Wang, W Pu, X Huang, L Qiu, Y Li, W Yu, H Zhao, X Liu, L He, L Zhang, Y Ji, J Lu, KO Lui, B Zhou
    Stem Cell Reports, 2019-02-14;12(3):624-638.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  78. Erythro-myeloid progenitors contribute endothelial cells to blood vessels
    Authors: Alice Plein, Alessandro Fantin, Laura Denti, Jeffrey W. Pollard, Christiana Ruhrberg
    Nature
  79. Direct Targeting of the mTOR (Mammalian Target of Rapamycin) Kinase Improves Endothelial Permeability in Drug-Eluting Stents—Brief Report
    Authors: Emanuel Harari, Liang Guo, Samantha L. Smith, Ka Hyun Paek, Raquel Fernandez, Atsushi Sakamoto et al.
    Arteriosclerosis, Thrombosis, and Vascular Biology
  80. Role of glutamine synthetase in angiogenesis beyond glutamine synthesis
    Authors: G Eelen, C Dubois, AR Cantelmo, J Goveia, U Brüning, M DeRan, G Jarugumill, J van Rijsse, G Saladino, F Comitani, A Zecchin, S Rocha, R Chen, H Huang, S Vandekeere, J Kalucka, C Lange, F Morales-Ro, B Cruys, L Treps, L Ramer, S Vinckier, K Brepoels, S Wyns, J Souffreau, L Schoonjans, WH Lamers, Y Wu, J Haustraete, J Hofkens, S Liekens, R Cubbon, B Ghesquière, M Dewerchin, FL Gervasio, X Li, JD van Buul, X Wu, P Carmeliet
    Nature, 2018-08-29;561(7721):63-69.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  81. The bone marrow is patrolled by NK cells that are primed and expand in response to systemic viral activation
    Authors: I Milo, R Blecher-Go, Z Barnett-It, R Bar-Ziv, O Tal, I Gurevich, T Feferman, I Drexler, I Amit, P Bousso, G Shakhar
    Eur. J. Immunol., 2018-05-02;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  82. Rhodocetin-?? selectively breaks the endothelial barrier of the tumor vasculature in HT1080 fibrosarcoma and A431 epidermoid carcinoma tumor models.
    Authors: Stephan Niland, Dorde Komljenov, Jadranka Macas, Thilo Bracht, Tobias Bäuerle, Stefan Liebner, Johannes A Eble
    Oncotarget, 2018-04-27;0(0):1949-2553.
    Species: Mouse
    Sample Types:
    Applications: IHC
  83. Gelatinolytic activity of autocrine matrix metalloproteinase-9 leads to endothelial de-arrangement in Moyamoya disease
    Authors: KG Blecharz-L, V Prinz, M Burek, D Frey, T Schenkel, SM Krug, M Fromm, P Vajkoczy
    J. Cereb. Blood Flow Metab., 2018-04-10;0(0):271678X187684.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  84. CD163+ macrophages promote angiogenesis and vascular permeability accompanied by inflammation in atherosclerosis
    Authors: L Guo, H Akahori, E Harari, SL Smith, R Polavarapu, V Karmali, F Otsuka, RL Gannon, RE Braumann, MH Dickinson, A Gupta, AL Jenkins, MJ Lipinski, J Kim, P Chhour, PS de Vries, H Jinnouchi, R Kutys, H Mori, MD Kutyna, S Torii, A Sakamoto, CU Choi, Q Cheng, ML Grove, MA Sawan, Y Zhang, Y Cao, FD Kolodgie, DP Cormode, DE Arking, E Boerwinkle, AC Morrison, J Erdmann, N Sotoodehni, R Virmani, AV Finn
    J. Clin. Invest., 2018-02-19;0(0):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  85. Polarized actin and VE-cadherin dynamics regulate junctional remodelling and cell migration during sprouting angiogenesis
    Authors: J Cao, M Ehling, S März, J Seebach, K Tarbashevi, T Sixta, ME Pitulescu, AC Werner, B Flach, E Montanez, E Raz, RH Adams, H Schnittler
    Nat Commun, 2017-12-20;8(1):2210.
    Species: Mouse, Rat
    Sample Types: Whole Tissue
    Applications: IHC
  86. Embryonic Stem Cell Differentiation to Functional Arterial Endothelial Cells through Sequential Activation of ETV2 and NOTCH1 Signaling by HIF1?
    Authors: KM Tsang, JS Hyun, KT Cheng, M Vargas, D Mehta, M Ushio-Fuka, L Zou, KV Pajcini, J Rehman, AB Malik
    Stem Cell Reports, 2017-08-03;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  87. Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD-induced myeloproliferation
    Authors: AJ Mead, WH Neo, N Barkas, S Matsuoka, A Giustacchi, R Facchini, S Thongjuea, L Jamieson, CAG Booth, N Fordham, C Di Genua, D Atkinson, O Chowdhury, E Repapi, N Gray, S Kharazi, SA Clark, T Bouriez, P Woll, T Suda, C Nerlov, SEW Jacobsen
    J. Exp. Med., 2017-06-21;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  88. Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming
    Authors: L Tian, A Goldstein, H Wang, H Ching Lo, I Sun Kim, T Welte, K Sheng, LE Dobrolecki, X Zhang, N Putluri, TL Phung, SA Mani, F Stossi, A Sreekumar, MA Mancini, WK Decker, C Zong, MT Lewis, XH Zhang
    Nature, 2017-04-03;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  89. HDL activation of endothelial sphingosine-1-phosphate receptor-1 (S1P1) promotes regeneration and suppresses fibrosis in the liver
    JCI Insight, 2016-12-22;1(21):e87058.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  90. PAR1 Scaffolds TGF beta RII to Downregulate TGF-beta Signaling and Activate ESC Differentiation to Endothelial Cells
    Authors: Haixia Gong, Shejuan An, Antonia Sassmann, Menglin Liu, Victoria Mastej, Manish Mittal et al.
    Stem Cell Reports
  91. Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells
    Nat Commun, 2016-08-12;7(0):12422.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  92. Targeting of Mesenchymal Stromal Cells by Cre-Recombinase Transgenes Commonly Used to Target Osteoblast Lineage Cells
    Authors: Jingzhu Zhang
    J Bone Miner Res, 2016-06-14;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  93. Genetic lineage tracing identifies in situ Kit-expressing cardiomyocytes.
    Authors: Liu Q, Yang R, Huang X, Zhang H, He L, Zhang L, Tian X, Nie Y, Hu S, Yan Y, Zhang L, Qiao Z, Wang Q, Lui K, Zhou B
    Cell Res, 2015-12-04;26(1):119-30.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  94. Granzyme B Deficiency Protects against Angiotensin II-Induced Cardiac Fibrosis.
    Authors: Shen Y, Cheng F, Sharma M, Merkulova Y, Raithatha S, Parkinson L, Zhao H, Westendorf K, Bohunek L, Bozin T, Hsu I, Ang L, Williams S, Bleackley R, Eriksson J, Seidman M, McManus B, Granville D
    Am J Pathol, 2015-11-25;186(1):87-100.
    Species: Mouse
    Sample Types: Recombinant Protein, Whole Tissue
    Applications: IHC-P, Western Blot
  95. Fibroblast Growth Factor 9 Imparts Hierarchy and Vasoreactivity to the Microcirculation of Renal Tumors and Suppresses Metastases.
    Authors: Yin H, Frontini M, Arpino J, Nong Z, O'Neil C, Xu Y, Balint B, Ward A, Chakrabarti S, Ellis C, Gros R, Pickering J
    J Biol Chem, 2015-07-16;290(36):22127-42.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  96. Vascular dysfunction and increased metastasis of B16F10 melanomas in Shb deficient mice as compared with their wild type counterparts.
    Authors: Zang G, Gustafsson K, Jamalpour M, Hong J, Genove G, Welsh M
    BMC Cancer, 2015-04-08;15(0):234.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  97. Platelet-derived SDF-1 primes the pulmonary capillary vascular niche to drive lung alveolar regeneration
    Authors: Shahin Rafii, Zhongwei Cao, Raphael Lis, Ilias I. Siempos, Deebly Chavez, Koji Shido et al.
    Nature Cell Biology
  98. Neuroligin 1 induces blood vessel maturation by cooperating with the alpha6 integrin.
    Authors: Samarelli A, Riccitelli E, Bizzozero L, Silveira T, Seano G, Pergolizzi M, Vitagliano G, Cascone I, Carpentier G, Bottos A, Primo L, Bussolino F, Arese M
    J Biol Chem, 2014-05-23;289(28):19466-76.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  99. Blood vessels pattern heparan sulfate gradients between their apical and basolateral aspects.
    Authors: Stoler-Barak, Liat, Moussion, Christin, Shezen, Elias, Hatzav, Miki, Sixt, Michael, Alon, Ronen
    PLoS ONE, 2014-01-22;9(1):e85699.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  100. Flk1+ and VE-cadherin+ endothelial cells derived from iPSCs recapitulates vascular development during differentiation and display similar angiogenic potential as ESC-derived cells.
    Authors: Kohler, Erin E, Wary, Kishore, Li, Fei, Chatterjee, Ishita, Urao, Norifumi, Toth, Peter T, Ushio-Fukai, Masuko, Rehman, Jalees, Park, Changwon, Malik, Asrar B
    PLoS ONE, 2013-12-30;8(12):e85549.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry, ICC
  101. Transcriptional targeting of primary and metastatic tumor neovasculature by an adenoviral type 5 roundabout4 vector in mice.
    Authors: Lu, Zhi Hong, Kaliberov, Sergey, Sohn, Rebecca, Kaliberova, Lyudmila, Curiel, David T, Arbeit, Jeffrey
    PLoS ONE, 2013-12-23;8(12):e83933.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  102. Control of retinoid levels by CYP26B1 is important for lymphatic vascular development in the mouse embryo.
    Authors: Bowles J, Secker G, Nguyen C, Kazenwadel J, Truong V, Frampton E, Curtis C, Skoczylas R, Davidson T, Miura N, Hong Y, Koopman P, Harvey N, Francois M
    Dev Biol, 2013-12-19;386(1):25-33.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  103. Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis.
    Authors: Ding B, Cao Z, Lis R, Nolan D, Guo P, Simons M, Penfold M, Shido K, Rabbany S, Rafii S
    Nature, 2013-11-20;505(7481):97-102.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  104. VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd.
    Authors: Sun Z, Li X, Massena S, Kutschera S, Padhan N, Gualandi L, Sundvold-Gjerstad V, Gustafsson K, Choy WW, Zang G, Quach M, Jansson L, Phillipson M, Abid MR, Spurkland A, Claesson-Welsh L
    J. Exp. Med., 2012-06-11;209(7):1363-77.
    Species: Mouse
    Sample Types: Tissue Homogenates, Whole Tissue
    Applications: IHC, Western Blot
  105. Unique Cell Type-Specific Junctional Complexes in Vascular Endothelium of Human and Rat Liver Sinusoids
    Authors: Cyrill Géraud, Konstantin Evdokimov, Beate K. Straub, Wiebke K. Peitsch, Alexandra Demory, Yvette Dörflinger et al.
    PLoS ONE
  106. Manganese superoxide dismutase expression in endothelial progenitor cells accelerates wound healing in diabetic mice.
    Authors: Marrotte EJ, Chen DD, Hakim JS
    J. Clin. Invest., 2010-11-08;120(12):4207-19.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  107. Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells.
    Authors: Butler JM, Nolan DJ, Vertes EL, Varnum-Finney B, Kobayashi H, Hooper AT, Seandel M, Shido K, White IA, Kobayashi M, Witte L, May C, Shawber C, Kimura Y, Kitajewski J, Rosenwaks Z, Bernstein ID, Rafii S
    Cell Stem Cell, 2010-03-05;6(3):251-64.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC-Fr, IHC-P
  108. Dysfunctional microvasculature as a consequence of shb gene inactivation causes impaired tumor growth.
    Authors: Funa NS, Kriz V, Zang G, Calounova G, Akerblom B, Mares J, Larsson E, Sun Y, Betsholtz C, Welsh M
    Cancer Res., 2009-02-17;69(5):2141-8.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  109. Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization.
    Authors: Mazzone M, Dettori D, Leite de Oliveira R, Loges S, Schmidt T, Jonckx B, Tian YM, Lanahan AA, Pollard P, Ruiz de Almodovar C, De Smet F, Vinckier S, Aragones J, Debackere K, Luttun A, Wyns S, Jordan B, Pisacane A, Gallez B, Lampugnani MG, Dejana E, Simons M, Ratcliffe P, Maxwell P, Carmeliet P
    Cell, 2009-02-12;136(5):839-51.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  110. Enhancing the reliability and throughput of neurosphere culture on hydrogel microwell arrays.
    Authors: Cordey M, Limacher M, Kobel S, Taylor V, Lutolf MP
    Stem Cells, 2008-07-31;26(10):2586-94.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC-Fr
  111. Genetic delivery of the murine equivalent of bevacizumab (avastin), an anti-vascular endothelial growth factor monoclonal antibody, to suppress growth of human tumors in immunodeficient mice.
    Authors: Watanabe M, Boyer JL, Hackett NR, Qiu J, Crystal RG
    Hum. Gene Ther., 2008-03-01;19(3):300-10.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  112. Lentiviral rescue of vascular endothelial growth factor receptor-2 expression in flk1-/- embryonic stem cells shows early priming of endothelial precursors.
    Authors: Li X, Edholm D, Lanner F, Breier G, Farnebo F, Dimberg A, Claesson-Welsh L
    Stem Cells, 2007-08-16;25(12):2987-95.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  113. Effect of gestational nutrition on vascular integrity in the murine placenta.
    Authors: Rutland CS, Latunde-Dada AO, Thorpe A, Plant R, Langley-Evans S, Leach L
    Placenta, 2006-08-23;28(7):734-42.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  114. Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy
    Authors: J Hu, S Dziumbla, J Lin, SI Bibli, S Zukunft, J de Mos, K Awwad, T Frömel, A Jungmann, K Devraj, Z Cheng, L Wang, S Fauser, CG Eberhart, A Sodhi, BD Hammock, S Liebner, OJ Müller, C Glaubitz, HP Hammes, R Popp, I Fleming
    Nature, 2017-12-06;552(7684):248-252.
  115. Semaphorin 7A Promotes VEGFA/VEGFR2-Mediated Angiogenesis and Intraplaque Neovascularization in ApoE-/- Mice
    Authors: Shuhong Hu, Yifei Liu, Tao You, Li Zhu
    Frontiers in Physiology
  116. Regeneration of the pulmonary vascular endothelium after viral pneumonia requires COUP-TF2
    Authors: Gan Zhao, Aaron I. Weiner, Katherine M. Neupauer, Maria Fernanda de Mello Costa, Gargi Palashikar, Stephanie Adams-Tzivelekidis et al.
    Science Advances
  117. Rasip1 regulates vertebrate vascular endothelial junction stability through Epac1-Rap1 signaling.
    Authors: Wilson CW, Parker LH, Hall CJ et al.
    Blood.
  118. Vascular Permeability Assay in Human Coronary and Mouse Brachiocephalic Arteries.
    Authors: Guo L, Fernandez R, Sakamoto A et al.
    Stem Cells International.

FAQs

No product specific FAQs exist for this product, however you may

View all Antibody FAQs
Loading...

Reviews for Mouse VE-Cadherin Antibody

Average Rating: 4 (Based on 1 Review)

5 Star
0%
4 Star
100%
3 Star
0%
2 Star
0%
1 Star
0%

Have you used Mouse VE-Cadherin Antibody?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Filter by:


Mouse VE-Cadherin Antibody
By Anonymous on 08/13/2021
Application: IHC Sample Tested: Skin tissue Species: Mouse
Immunohistochemistry Mouse VE-Cadherin Antibody AF1002