Proteome Profiler Human Cytokine Array Kit, Panel A
Proteome Profiler Human Cytokine Array Kit, Panel A Summary
Proteome Profiler™ Human Cytokine Array Kit, Panel A
Principle of the Assay
The Proteome Profiler Human Cytokine Array Kit, Panel A is a membrane-based sandwich immunoassay. Samples are mixed with a cocktail of biotinylated detection antibodies (Step 1) and then incubated with the array membrane which is spotted in duplicate with capture antibodies to specific target proteins (Step 2). Captured proteins are visualized using chemiluminescent detection reagents (Step 3). The signal produced is proportional to the amount of analyte bound.
Why Use an Antibody Array to Detect Multiple Cytokines?
Determining the expression of multiple cytokines in a single sample can be expensive, time consuming and can require specialized equipment. Performing multiple immunoprecipitations and Western blots requires time, labor, and reagents. The use of a multiplex antibody array to detect multiple cytokines in a single sample can be cost-effective and also save time and sample.
Kit Contents
- Rectangular 4-Well Multi-dish
- 4 Human Cytokine Array, Panel A nitrocellulose membranes spotted with 36 different antibodies to human cytokines, chemokines, and acute phase proteins
- Array Buffer 4
- Array Buffer 5
- Chemi Reagent 1
- Chemi Reagent 2
- Detection Antibody Cocktail, Human Cytokine Array, Panel A
- Streptavidin-HRP
- Transparency Overlay Template
- Wash Buffer Concentrate (25X)
For a complete list of the kit contents and necessary materials, please see the Materials Provided/Other Supplies Required sections of the product datasheet.
Simultaneously detect the levels of these cytokines, chemokines, and acute phase proteins in a single sample. | ||
C5a | IL-4 | IL-32 alpha |
CD40 Ligand/TNFSF5 | IL-5 | CXCL10/IP-10 |
G-CSF | IL-6 | CXCL11/I-TAC |
GM-CSF | IL-8 | CCL2/MCP-1 |
CXCL1/GRO alpha | IL-10 | MIF |
CCL1/I-309 | IL-12 p70 | CCL3/MIP-1 alpha |
ICAM-1 | IL-13 | CCL4/MIP-1 beta |
IFN-gamma | IL-16 | CCL5/RANTES |
IL-1 alpha/IL-1F1 | IL-17 | CXCL12/SDF-1 |
IL-1 beta/IL-1F2 | IL-17E | Serpin E1/PAI-1 |
IL-1ra/IL-1F3 | IL-23 | TNF-alpha |
IL-2 | IL-27 | TREM-1 |
Assays for Analytes represented in the Human XL Cytokine Array Kit, Panel A
See Details
Analyte | Quantikine® ELISA Kits | Quantikine® HS (High Sensitivity) ELISA Kits | QuantiGlo® ELISA Kits | DuoSet® ELISA Development Systems |
C5a | DY2037 | |||
CD40 Ligand | DCDL40 | DY617 | ||
G-CSF | DCS50 | HSTCS0 | DY214 | |
GM-CSF | DGM00 | HSGM0 | DY215 | |
CXCL1/GRO alpha | DGR00 | DY275 | ||
CCL1/I-309 | DY272 | |||
ICAM-1 | DCD5400 | DY720 | ||
IFN-gamma | DIF50 | DY285 | ||
IL-1 alpha | DLA50 | DY200 | ||
IL-1 beta | DLB50 | HSLB00C | QLB00B | DY201 |
IL-1ra | DRA00B | DY280 | ||
IL-2 | D2050 | Q2000B | DY202 | |
IL-4 | D4050 | HS400 | Q4000 | DY204 |
IL-5 | D5000 | DY205 | ||
IL-6 | D6050 | HS600B | Q6000B | DY206 |
CXCL8/IL-8 | D8000C | HS800 | Q8000B | DY208 |
IL-10 | D1000B | HS100C | Q1000 | DY217B |
IL-12 p70 | D1200 | HS120 | DY1270 | |
IL-13 | D1300 | DY213 | ||
IL-16 | D1600 | DY316 | ||
IL-17 | D1700 | DY317 | ||
IL-17E | ||||
IL-23 | D2300B | |||
IL-27 | ||||
IL-32 alpha | ||||
CXCL10/IP-10 | DIP100 | DY266 | ||
CXCL11/I-TAC | DCX110 | DY672 | ||
CCL2/MCP-1 | DCP00 | DY279 | ||
MIF | DMF00 | DY289 | ||
CCL3/MIP-1 alpha | DMA00 | DY270 | ||
CCL4/MIP-1 beta | DMB00 | DY271 | ||
Serpin E1/PAI-1 | DSE100 | |||
CCL5/RANTES | DRN00B | DY278 | ||
CXCL12/SDF-1 | DSA00 | DY350 | ||
TNF-alpha | DTA00C | HSTA00D | QTA00B | DY210 |
TREM-1 | DY1278 |
Stability and Storage
Store the unopened kit at 2 °C to 8 °C. Do not use past kit expiration date.
Data Examples
View Larger Image |
Detection of Multiple Human Cytokines in Cell Culture Supernates. Cells were treated as described below. Following treatment, cell culture supernates were analyzed using the Proteome Profiler Human Cytokine Array Kit, Panel A. Human peripheral blood mononuclear cells were treated with phytohemagglutinin (PHA) for 24 hours. B. TF-1 human erythroleukemia cells were treated with phorbol 12-myristate 13-acetate (PMA) for 24 hours. C. THP-1 human acute monocytic leukemia cells were treated with lipopolysaccharide (LPS) for 16 hours. |
View Larger Image |
Detection of Multiple Cytokines in Human Serum. Human serum was collected from four donors (A – D), and the relative levels of multiple cytokines were determined using the Proteome Profiler Human Cytokine Array Kit, Panel A. |
View Larger Image |
Detection of Multiple Cytokines in Human Tissues and Cell Lysates. Extracts were generated from human tissue or cell lines indicated below and analyzed for relative cytokine expression using the Proteome Profiler Human Cytokine Array Kit, Panel A. A. Normal human lung tissue. B. Malignant human lung cancer tissue. C. Human A431 epithelial carcinoma cells. The number on each array image corresponds to one differentially expressed cytokine and is shown in bar graph form in the right panel. |
Specifications
Product Datasheets
Citations for Proteome Profiler Human Cytokine Array Kit, Panel A
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Three-dimensional human neural culture on a chip recapitulating neuroinflammation and neurodegeneration
Authors: Kang, YJ;Diep, YN;Tran, M;Tran, VTA;Ambrin, G;Ngo, H;Cho, H;
Nature protocols 2023-08-04
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Optineurin deficiency impairs autophagy to cause interferon beta overproduction and increased survival of mice following viral infection
Authors: Fukushi, M;Ohsawa, R;Okinaka, Y;Oikawa, D;Kiyono, T;Moriwaki, M;Irie, T;Oda, K;Kamei, Y;Tokunaga, F;Sotomaru, Y;Maruyama, H;Kawakami, H;Sakaguchi, T;
PloS one 2023-06-23
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Cancer-associated mesothelial cell-derived ANGPTL4 and STC1 promote the early steps of ovarian cancer metastasis
Authors: P Bajwa, K Kordylewic, A Bilecz, RR Lastra, K Wroblewski, Y Rinkevich, E Lengyel, HA Kenny
JCI Insight, 2023-03-22;0(0):. 2023-03-22
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The early neutrophil-committed progenitors aberrantly differentiate into immunoregulatory monocytes during emergency myelopoiesis
Authors: N Ikeda, H Kubota, R Suzuki, M Morita, A Yoshimura, Y Osada, K Kishida, D Kitamura, A Iwata, S Yotsumoto, D Kurotaki, K Nishimura, A Nishiyama, T Tamura, T Kamatani, T Tsunoda, M Murakawa, Y Asahina, Y Hayashi, H Harada, Y Harada, A Yokota, H Hirai, T Seki, M Kuwahara, M Yamashita, S Shichino, M Tanaka, K Asano
Cell Reports, 2023-02-28;42(3):112165. 2023-02-28
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Cyanobacterial Harmful Bloom Lipopolysaccharides Induce Pro-Inflammatory Effects in Immune and Intestinal Epithelial Cells In Vitro
Authors: V Sko?ková, O Vaší?ek, E Sychrová, I Sovadinová, P Babica, L Šindlerová
Toxins, 2023-02-21;15(3):. 2023-02-21
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Vitamin D (1alpha,25(OH)2D3) supplementation minimized multinucleated giant cells formation and inflammatory response during Burkholderia pseudomallei infection in human lung epithelial cells
Authors: P Mattrasong, S Wongkaewkh, S Taweechais, S Chareonsud, T Techawiwat, T Ngamsiri, S Kanthawong
PLoS ONE, 2023-02-09;18(2):e0280944. 2023-02-09
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The D405N Mutation in the Spike Protein of SARS-CoV-2 Omicron BA.5 Inhibits Spike/Integrins Interaction and Viral Infection of Human Lung Microvascular Endothelial Cells
Authors: A Bugatti, F Filippini, S Messali, M Giovanetti, C Ravelli, A Zani, M Ciccozzi, A Caruso, F Caccuri
Viruses, 2023-01-24;15(2):. 2023-01-24
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Radiofrequency Ablation Remodels the Tumor Microenvironment and Promotes Neutrophil-Mediated Abscopal Immunomodulation in Pancreatic Cancer
Authors: EY Faraoni, BJ O'Brien, LN Strickland, BK Osborn, V Mota, J Chaney, CL Atkins, P Cen, J Rowe, J Cardenas, KL Poulsen, CJ Wray, NC Thosani, JM Bailey-Lun
Cancer Immunology Research, 2023-01-03;11(1):4-12. 2023-01-03
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EGFR-Tyrosine Kinase Inhibitors Induced Activation of the Autocrine CXCL10/CXCR3 Pathway through Crosstalk between the Tumor and the Microenvironment in EGFR-Mutant Lung Cancer
Authors: SH Hong, N Kang, O Kim, SA Hong, J Park, J Kim, MA Lee, J Kang
Cancers, 2022-12-25;15(1):. 2022-12-25
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Inhibition of triple negative breast cancer-associated inflammation and progression by N- acylethanolamine acid amide hydrolase (NAAA)
Authors: O Benchama, MS Malamas, K Praveen, EC Ethier, MK Williams, A Makriyanni, HK Avraham
Scientific Reports, 2022-12-23;12(1):22255. 2022-12-23
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Clozapine Suppresses the Gene Expression and the Production of Cytokines and Up-Regulates Cyclooxygenase 2 mRNA in Human Astroglial Cells
Authors: Y Yuhas, S Ashkenazi, E Berent, A Weizman
Brain sciences, 2022-12-12;12(12):. 2022-12-12
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Non-small cell lung cancer-derived exosomes promote proliferation, phagocytosis, and secretion of microglia via exosomal microRNA in the metastatic microenvironment
Authors: P Chen, Y Li, R Liu, Y Xie, Y Jin, M Wang, Z Yu, W Wang, X Luo
Translational Oncology, 2022-12-01;27(0):101594. 2022-12-01
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Successful targeting of PD-1/PD-L1 with chimeric antigen receptor-natural killer cells and nivolumab in a humanized mouse cancer model
Authors: WN Liu, WY So, SL Harden, SY Fong, MXY Wong, WWS Tan, SY Tan, JKL Ong, R Rajarethin, M Liu, JY Cheng, L Suteja, JPS Yeong, NG Iyer, DW Lim, Q Chen
Science Advances, 2022-11-23;8(47):eadd1187. 2022-11-23
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Biallelic germline mutations in MAD1L1 induce a syndrome of aneuploidy with high tumor susceptibility
Authors: C Villarroya, A Osorio, R Torres-Rui, D Gómez-Sánc, M Trakala, A Sánchez-Be, F Mercadillo, B Hurtado, B Pitarch, A Hernández-, A Gómez-Catu, D Rueda, J Perea, S Rodríguez-, M Malumbres, M Urioste
Science Advances, 2022-11-02;8(44):eabq5914. 2022-11-02
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Metabolic control of CD47 expression through LAT2-mediated amino acid uptake promotes tumor immune evasion
Authors: Z Wang, B Li, S Li, W Lin, Z Wang, S Wang, W Chen, W Shi, T Chen, H Zhou, E Yinwang, W Zhang, H Mou, X Chai, J Zhang, Z Lu, Z Ye
Nature Communications, 2022-10-23;13(1):6308. 2022-10-23
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Profound Effects of Dexamethasone on the Immunological State, Synthesis and Secretion Capacity of Human Testicular Peritubular Cells
Authors: YK Stepanov, JD Speidel, C Herrmann, N Schmid, R Behr, FM Köhn, JB Stöckl, U Pickl, M Trottmann, T Fröhlich, A Mayerhofer, H Welter
Cells, 2022-10-09;11(19):. 2022-10-09
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Immune activation is essential for the antitumor activity of EZH2 inhibition in urothelial carcinoma
Authors: A Piunti, K Meghani, Y Yu, AG Robertson, JR Podojil, KA McLaughlin, Z You, D Fantini, M Chiang, Y Luo, L Wang, N Heyen, J Qian, SD Miller, A Shilatifar, JJ Meeks
Science Advances, 2022-10-05;8(40):eabo8043. 2022-10-05
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Analysis of rheumatoid- vs psoriatic arthritis synovial fluid reveals differential macrophage (CCR2) and T helper subsets (STAT3/4 and FOXP3) activation
Authors: F Caso, A Saviano, M Tasso, F Raucci, N Marigliano, S Passavanti, P Frallonard, R Ramonda, V Brancaleon, M Bucci, R Scarpa, L Costa, F Maione
Autoimmunity reviews, 2022-10-01;21(12):103207. 2022-10-01
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Cytokine profile of human limbal myofibroblasts: Key players in corneal antiviral response
Authors: A Domínguez-, Y Garfias
Cytokine, 2022-09-29;160(0):156047. 2022-09-29
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The lysosomal proteome of senescent cells contributes to the senescence secretome
Authors: M Rovira, R Sereda, D Pladevall-, V Ramponi, I Marin, M Maus, J Madrigal-M, A Díaz, F García, J Muñoz, AM Cuervo, M Serrano
Aging Cell, 2022-09-10;0(0):e13707. 2022-09-10
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Obstructive Sleep Apnea Syndrome In Vitro Model: Controlled Intermittent Hypoxia Stimulation of Human Stem Cells-Derived Cardiomyocytes
Authors: D Regev, S Etzion, H Haddad, J Gopas, A Goldbart
International Journal of Molecular Sciences, 2022-09-07;23(18):. 2022-09-07
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Exosomal B7-H4 from irradiated glioblastoma cells contributes to increase FoxP3 expression of differentiating Th1 cells and promotes tumor growth
Authors: Y Tian, C Liu, Z Li, M Ai, B Wang, K Du, W Liu, H Wang, P Yu, C Chen, J Lin, A Xu, R Li, W Zhang, Y Yuan
Redox Biology, 2022-08-27;56(0):102454. 2022-08-27
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Detection of Leptomonas seymouri narna-like virus in serum samples of visceral leishmaniasis patients and its possible role in disease pathogenesis
Authors: S Sukla, H Nath, M Kamran, SA Ejazi, N Ali, P Das, V Ravichandi, S Roy, S Biswas
Scientific Reports, 2022-08-24;12(1):14436. 2022-08-24
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A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states
Authors: NM Dräger, SM Sattler, CT Huang, OM Teter, K Leng, SH Hashemi, J Hong, G Aviles, CD Clelland, L Zhan, JC Udeochu, L Kodama, AB Singleton, MA Nalls, J Ichida, ME Ward, F Faghri, L Gan, M Kampmann
Nature Neuroscience, 2022-08-11;0(0):. 2022-08-11
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Interplay of Helicobacter pylori, fibroblasts, and cancer cells induces fibroblast activation and serpin E1 expression by cancer cells to promote gastric tumorigenesis
Authors: X Chen, W Chen, Y Zhao, Q Wang, W Wang, Y Xiang, H Yuan, Y Xie, J Zhou
Journal of Translational Medicine, 2022-07-21;20(1):322. 2022-07-21
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Stalled replication fork protection limits cGAS-STING and P-body-dependent innate immune signalling
Authors: A Emam, X Wu, S Xu, L Wang, S Liu, B Wang
Nature Cell Biology, 2022-07-11;24(7):1154-1164. 2022-07-11
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MIF/CXCR4 signaling axis contributes to survival, invasion, and drug resistance of metastatic neuroblastoma cells in the bone marrow microenvironment
Authors: L Garcia-Ger, M García, A Garrido-Ga, S Gómez-Gonz, M Torrebadel, E Prada, G Pascual-Pa, O Muñoz, S Perez-Jaum, I Lemos, N Salvador, M Vila-Ubach, A Doncel-Req, M Suñol, AM Carcaboso, J Mora, C Lavarino
BMC Cancer, 2022-06-17;22(1):669. 2022-06-17
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PRRX1 is a master transcription factor of stromal fibroblasts for myofibroblastic lineage progression
Authors: KW Lee, SY Yeo, JR Gong, OJ Koo, I Sohn, WY Lee, HC Kim, SH Yun, YB Cho, MA Choi, S An, J Kim, CO Sung, KH Cho, SH Kim
Nature Communications, 2022-05-19;13(1):2793. 2022-05-19
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Paracrine Interaction of Cholangiocellular Carcinoma with Cancer-Associated Fibroblasts and Schwann Cells Impact Cell Migration
Authors: JP Gundlach, J Kerber, A Hendricks, A Bernsmeier, C Halske, C Röder, T Becker, C Röcken, F Braun, S Sebens, N Heits
Journal of Clinical Medicine, 2022-05-15;11(10):. 2022-05-15
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Alpha-Linolenic Acid Modulates T Cell Incorporation in a 3D Tissue-Engineered Psoriatic Skin Model
Authors: S Morin, M Simard, G Rioux, P Julien, R Pouliot
Cells, 2022-04-30;11(9):. 2022-04-30
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Endothelial inflammation and neutrophil transmigration are modulated by extracellular matrix composition in an inflammation-on-a-chip model
Authors: RB Riddle, K Jennbacken, KM Hansson, MT Harper
Scientific Reports, 2022-04-27;12(1):6855. 2022-04-27
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ESR1 mutant breast cancers show elevated basal cytokeratins and immune activation
Authors: Z Li, O McGinn, Y Wu, A Bahreini, NM Priedigkei, K Ding, S Onkar, C Lampenfeld, CA Sartorius, L Miller, M Rosenzweig, O Cohen, N Wagle, JK Richer, WJ Muller, L Buluwela, S Ali, TC Bruno, DAA Vignali, Y Fang, L Zhu, GC Tseng, J Gertz, JM Atkinson, AV Lee, S Oesterreic
Nature Communications, 2022-04-19;13(1):2011. 2022-04-19
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Mycobacterium avium-intracellulare complex promote release of pro-inflammatory enzymes matrix metalloproteinases by inducing neutrophil extracellular trap formation
Authors: K Nakamura, H Nakayama, S Sasaki, K Takahashi, K Iwabuchi
Scientific Reports, 2022-04-11;12(1):5181. 2022-04-11
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Compound heterozygous variants in OTULIN are associated with fulminant atypical late-onset ORAS
Authors: J Zinngrebe, B Moepps, T Monecke, P Gierschik, F Schlichtig, TFE Barth, G Strau beta, E Boldrin, C Posovszky, A Schulz, O Beringer, E Rieser, EM Jacobsen, MR Lorenz, K Schwarz, U Pannicke, H Walczak, D Niessing, C Schuetz, P Fischer-Po, KM Debatin
Embo Molecular Medicine, 2022-02-16;0(0):e14901. 2022-02-16
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Inhibition of the VEGF signaling pathway attenuates tumor?associated macrophage activity in liver cancer
Authors: S Okikawa, Y Morine, Y Saito, S Yamada, K Tokuda, H Teraoku, K Miyazaki, S Yamashita, T Ikemoto, S Imura, M Shimada
Oncology reports, 2022-02-16;47(4):. 2022-02-16
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TNF-alpha Activating Osteoclasts in Patients with Psoriatic Arthritis Enhances the Recruitment of Osteoclast Precursors: A Plausible Role of WNT5A-MCP-1 in Osteoclast Engagement in Psoriatic Arthritis
Authors: SH Lin, JC Ho, SC Li, YW Cheng, CY Hsu, WY Chou, CC Hsiao, CH Lee
International Journal of Molecular Sciences, 2022-01-15;23(2):. 2022-01-15
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Postoperative Pulmonary Hemodynamics and Systemic Inflammatory Response in Pediatric Patients Undergoing Surgery for Congenital Heart Defects
Authors: MFS Souza, JG Penha, NY Maeda, FRBG Galas, KCO Abud, ES Carvalho, AM Thomaz, CRP Castro, J Pereira, AA Lopes
Mediators of Inflammation, 2022-01-15;2022(0):3977585. 2022-01-15
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The Functional Role of IgA in the IgM/IgA-Enriched Immunoglobulin Preparation Trimodulin
Authors: F Bohländer, S Wei beta müller, D Riehl, M Gutscher, J Schüttrump, S Faust
Biomedicines, 2021-12-03;9(12):. 2021-12-03
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Analysis of the Influence of Jaw Periosteal Cells on Macrophages Phenotype Using an Innovative Horizontal Coculture System
Authors: F He, F Umrath, C von Ohle, S Reinert, D Alexander
Biomedicines, 2021-11-24;9(12):. 2021-11-24
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Calciprotein Particles Link Disturbed Mineral Homeostasis with Cardiovascular Disease by Causing Endothelial Dysfunction and Vascular Inflammation
Authors: DK Shishkova, EA Velikanova, LA Bogdanov, MY Sinitsky, AE Kostyunin, AV Tsepokina, OV Gruzdeva, AV Mironov, RA Mukhamadiy, TV Glushkova, EO Krivkina, VG Matveeva, ON Hryachkova, VE Markova, YA Dyleva, EV Belik, AV Frolov, AR Shabaev, OS Efimova, AN Popova, VY Malysheva, RP Kolmykov, OG Sevostyano, DM Russakov, VF Dolganyuk, AK Gutakovsky, YA Zhivodkov, AS Kozhukhov, EB Brusina, ZR Ismagilov, OL Barbarash, AE Yuzhalin, AG Kutikhin
International Journal of Molecular Sciences, 2021-11-18;22(22):. 2021-11-18
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Chromium Oxide Nanoparticle Impaired Osteogenesis and Cellular Response to Mechanical Stimulus
Authors: J Chen, J Ding, Y Wu, S Zhang, N Zheng, J Yang, J Xu
International Journal of Nanomedicine, 2021-09-03;16(0):6157-6170. 2021-09-03
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CFH Loss in Human RPE Cells Leads to Inflammation and Complement System Dysregulation via the NF-kappaB Pathway
Authors: A Armento, TL Schmidt, I Sonntag, DA Merle, MA Jarboui, E Kilger, SJ Clark, M Ueffing
International Journal of Molecular Sciences, 2021-08-13;22(16):. 2021-08-13
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USP12 downregulation orchestrates a protumourigenic microenvironment and enhances lung tumour resistance to PD-1 blockade
Authors: Z Yang, G Xu, B Wang, Y Liu, L Zhang, T Jing, M Tang, X Xu, K Jiao, L Xiang, Y Fu, D Tang, X Zhang, W Jin, G Zhuang, X Zhao, Y Liu
Nature Communications, 2021-08-11;12(1):4852. 2021-08-11
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3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine
Authors: CC Clement, A D'Alessand, S Thangaswam, S Chalmers, R Furtado, S Spada, G Mondanelli, F Ianni, S Gehrke, M Gargaro, G Manni, LCL Cara, P Runge, WL Tsai, S Karaman, J Arasa, R Fernandez-, A Beck, A Macchiarul, M Gadina, C Halin, F Fallarino, M Skobe, M Veldhoen, S Moretti, S Formenti, S Demaria, RK Soni, R Galarini, R Sardella, G Lauvau, C Putterman, K Alitalo, U Grohmann, L Santambrog
Nature Communications, 2021-07-21;12(1):4447. 2021-07-21
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G-quadruplex binders as cytostatic modulators of innate immune genes in cancer cells
Authors: G Miglietta, M Russo, RC Duardo, G Capranico
Nucleic Acids Research, 2021-07-09;0(0):. 2021-07-09
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SARS-CoV-2 Infection Remodels the Phenotype and Promotes Angiogenesis of Primary Human Lung Endothelial Cells
Authors: F Caccuri, A Bugatti, A Zani, A De Palma, D Di Silvest, E Manocha, F Filippini, S Messali, P Chiodelli, G Campisi, S Fiorentini, F Facchetti, P Mauri, A Caruso
Microorganisms, 2021-07-03;9(7):. 2021-07-03
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Differentiation of human induced pluripotent stem cells to authentic macrophages using a defined, serum-free, open-source medium
Authors: A Vaughan-Ja, S Stodolak, KH Ebrahimi, C Browne, PK Reardon, E Pires, J Gilbert-Ja, SA Cowley, WS James
Stem Cell Reports, 2021-06-24;0(0):. 2021-06-24
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Crosstalk between astrocytes and microglia results in increased degradation of &alpha-synuclein and amyloid-&beta aggregates
Authors: J Rostami, T Mothes, M Kolahdouza, O Eriksson, M Moslem, J Bergström, M Ingelsson, P O'Callagha, LM Healy, A Falk, A Erlandsson
Journal of Neuroinflammation, 2021-06-03;18(1):124. 2021-06-03
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WNT5A inhibition alters the malignant peripheral nerve sheath tumor microenvironment and enhances tumor growth
Authors: CS Thomson, J Pundavela, MR Perrino, RA Coover, K Choi, KE Chaney, TA Rizvi, DA Largaespad, N Ratner
Oncogene, 2021-06-02;40(24):4229-4241. 2021-06-02
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PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR
Authors: S Ghosh, NB Nataraj, A Noronha, S Patkar, A Sekar, S Mukherjee, S Winograd-K, L Kramarski, A Verma, M Lindzen, DD Garcia, J Green, G Eisenberg, H Gil-Henn, A Basu, Y Lender, S Weiss, M Oren, M Lotem, B Geiger, E Ruppin, Y Yarden
Cell Reports, 2021-05-25;35(8):109181. 2021-05-25
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Celastrol attenuates the inflammatory response by inhibiting IL?1&beta expression in triple?negative breast cancer cells
Authors: D You, Y Jeong, SY Yoon, S A Kim, SW Kim, SJ Nam, JE Lee, S Kim
Oncology reports, 2021-04-13;45(6):. 2021-04-13
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Musashi-1 Regulates MIF1-Mediated M2 Macrophage Polarization in Promoting Glioblastoma Progression
Authors: YP Yang, CS Chien, AA Yarmishyn, MS Chan, AC Lee, YW Chen, PI Huang, HI Ma, WL Lo, Y Chien, WC Lin, ML Wang, MT Chen
Cancers, 2021-04-09;13(8):. 2021-04-09
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P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression
Authors: E Yeini, P Ofek, S Pozzi, N Albeck, D Ben-Shusha, G Tiram, S Golan, R Kleiner, R Sheinin, S Israeli Da, S Reich-Zeli, R Grossman, Z Ram, H Brem, TM Hyde, P Magod, D Friedmann-, A Madi, R Satchi-Fai
Nature Communications, 2021-03-26;12(1):1912. 2021-03-26
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Caspase-Cleaved Keratin 18 Measurements Identified Ongoing Liver Injury after Bariatric Surgery
Authors: F Hempel, M Roderfeld, LJ Müntnich, J Albrecht, Z Oruc, B Arneth, T Karrasch, J Pons-Kühne, W Padberg, H Renz, A Schäffler, E Roeb
Journal of Clinical Medicine, 2021-03-16;10(6):. 2021-03-16
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Danegaptide Prevents TGF&beta1-Induced Damage in Human Proximal Tubule Epithelial Cells of the Kidney
Authors: PE Squires, GW Price, U Mouritzen, JA Potter, BM Williams, CE Hills
International Journal of Molecular Sciences, 2021-03-10;22(6):. 2021-03-10
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Acid-electrolyzed functional water-induces Interleukin-1&alpha release from Intracellular Storage Sites in Oral Squamous Cell Carcinoma
Authors: T Takemoto, R Kaetsu, M Hanayama, Y Ishiyama, M Sadamura, K Nishio, M Tsunoda, M Asano, M Motoyoshi
International Journal of Medical Sciences, 2021-02-18;18(8):1746-1752. 2021-02-18
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The interaction between cancer associated fibroblasts and tumor associated macrophages via the osteopontin pathway in the tumor microenvironment of hepatocellular carcinoma
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The Effect of a p38 Mitogen-Activated Protein Kinase Inhibitor on Cellular Senescence of Cultivated Human Corneal Endothelial Cells
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Invest. Ophthalmol. Vis. Sci., 2017-07-01;58(9):3325-3334. 2017-07-01
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Downregulation of UHRF1 increases tumor malignancy by activating the CXCR4/AKT-JNK/IL-6/Snail signaling axis in hepatocellular carcinoma cells
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NOX2-dependent ATM kinase activation dictates pro-inflammatory macrophage phenotype and improves effectiveness to radiation therapy
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Disruption of outer blood-retinal barrier by Toxoplasma gondii-infected monocytes is mediated by paracrinely activated FAK signaling
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PLoS ONE, 2017-04-13;12(4):e0175159. 2017-04-13
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Orai and TRPC channel characterization in Fc?RI-mediated calcium signaling and mediator secretion in human mast cells
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Physiol Rep, 2017-03-01;5(5):. 2017-03-01
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Surface-bound galectin-4 regulates gene transcription and secretion of chemokines in human colorectal cancer cell lines
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Tumour Biol, 2017-03-01;39(3):1010428317691. 2017-03-01
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Lipocalin-2 Promotes Pancreatic Ductal Adenocarcinoma by Regulating Inflammation in the Tumor Microenvironment
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Cancer Res, 2017-03-01;0(0):. 2017-03-01
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Serum cytokine/chemokine profiles in patients with dengue fever (DF) and dengue hemorrhagic fever (FHD) by using protein array
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J. Clin. Virol, 2017-02-17;89(0):39-45. 2017-02-17
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The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2
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Mol. Cell, 2017-02-16;65(4):730-742.e5. 2017-02-16
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Phenotypic and Functional Alterations of Hematopoietic Stem and Progenitor Cells in an In Vitro Leukemia-Induced Microenvironment
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Int J Mol Sci, 2017-02-14;18(2):. 2017-02-14
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A Proinflammatory Secretome Mediates the Impaired Immunopotency of Human Mesenchymal Stromal Cells in Elderly Patients with Atherosclerosis
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Stem Cells Transl Med, 2017-02-14;6(4):1132-1140. 2017-02-14
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Tumor-associated mesenchymal stem-like cells provide extracellular signaling cue for invasiveness of glioblastoma cells
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Oncotarget, 2017-01-03;8(1):1438-1448. 2017-01-03
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Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis
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Autophagy, 2017-01-01;0(0):0. 2017-01-01
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Multimodal Regulation of NET Formation in Pregnancy: Progesterone Antagonizes the Pro-NETotic Effect of Estrogen and G-CSF
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Front Immunol, 2016-12-05;7(0):565. 2016-12-05
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Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents
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Oncotarget, 2016-11-22;7(47):77205-77224. 2016-11-22
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MicroRNAs regulate cytokine responses in gingival epithelial cells
Infect Immun, 2016-11-18;0(0):. 2016-11-18
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Role of the B Allele of Influenza A Virus Segment 8 in Setting Mammalian Host Range and Pathogenicity
Authors: Paul Digard
J. Virol., 2016-09-29;90(20):9263-84. 2016-09-29
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Human and mouse monocytes display distinct signalling and cytokine profiles upon stimulation with FFAR2/FFAR3 short-chain fatty acid receptor agonists
Sci Rep, 2016-09-26;6(0):34145. 2016-09-26
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Neurotensin stimulates sortilin and mTOR in human microglia inhibitable by methoxyluteolin, a potential therapeutic target for autism
Proc Natl Acad Sci USA, 2016-09-23;0(0):. 2016-09-23
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MEK and TAK1 regulate apoptosis in colon cancer cells with KRAS-dependent activation of proinflammatory signaling
Mol Cancer Res, 2016-09-21;0(0):. 2016-09-21
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The oncometabolite R-2-hydroxyglutarate activates NF-?B-dependent tumor-promoting stromal niche for acute myeloid leukemia cells
Sci Rep, 2016-08-31;6(0):32428. 2016-08-31
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Serum Cytokines in Young Pediatric Patients with Congenital Cardiac Shunts and Altered Pulmonary Hemodynamics
Mediators Inflamm, 2016-08-30;2016(0):7672048. 2016-08-30
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The MNK-1/eIF4E pathway as a new therapeutic pathway to target inflammation and remodelling in asthma
Cell Signal, 2016-07-11;28(10):1555-1562. 2016-07-11
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MSC from fetal and adult lungs possess lung-specific properties compared to bone marrow-derived MSC.
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Sci Rep, 2016-07-06;6(0):29160. 2016-07-06
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IGF1R as a Key Target in High Risk, Metastatic Medulloblastoma
Authors: Matthew N Svalina
Sci Rep, 2016-06-03;6(0):27012. 2016-06-03
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NF-?B-HOTAIR axis links DNA damage response, chemoresistance and cellular senescence in ovarian cancer
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Oncogene, 2016-04-04;0(0):. 2016-04-04
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Soluble alpha-enolase activates monocytes by CD14-dependent TLR4 signalling pathway and exhibits a dual function
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Sci Rep, 2016-03-30;6(0):23796. 2016-03-30
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Cisplatin-induced mesenchymal stromal cells-mediated mechanism contributing to decreased antitumor effect in breast cancer cells.
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Cell Commun Signal, 2016-01-12;14(1):4. 2016-01-12
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Activation of IFN/STAT1 signalling predicts response to chemotherapy in oestrogen receptor-negative breast cancer
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Br. J. Cancer, 2015-12-22;114(2):177-87. 2015-12-22
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Fibrocytes Differ from Macrophages but Can Be Infected with HIV-1.
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J Immunol, 2015-09-28;195(9):4341-50. 2015-09-28
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In vitro Study of a Novel Stent Coating Using Modified CD39 Messenger RNA to Potentially Reduce Stent Angioplasty-Associated Complications.
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Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts.
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Blood, 2015-06-22;126(9):1106-17. 2015-06-22
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High EMT Signature Score of Invasive Non-Small Cell Lung Cancer (NSCLC) Cells Correlates with NFkappaB Driven Colony-Stimulating Factor 2 (CSF2/GM-CSF) Secretion by Neighboring Stromal Fibroblasts.
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PLoS ONE, 2015-04-28;10(4):e0124283. 2015-04-28
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J Transl Med, 2015-04-24;13(0):129. 2015-04-24
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XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer.
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Cytokine profiling of docetaxel-resistant castration-resistant prostate cancer.
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Characterization of dedifferentiating human mature adipocytes from the visceral and subcutaneous fat compartments: fibroblast-activation protein alpha and dipeptidyl peptidase 4 as major components of matrix remodeling.
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Macrophage migration inhibitory factor-CXCR4 is the dominant chemotactic axis in human mesenchymal stem cell recruitment to tumors.
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J Immunol, 2015-02-23;194(7):3463-74. 2015-02-23
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Contact-dependent depletion of hydrogen peroxide by catalase is a novel mechanism of myeloid-derived suppressor cell induction operating in human hepatic stellate cells.
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Soluble CD54 induces human endothelial cells ex vivo expansion useful for cardiovascular regeneration and tissue engineering application.
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The role of TLR8 signaling in acute myeloid leukemia differentiation.
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Leukemia, 2014-10-06;29(4):918-26. 2014-10-06
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Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis.
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Improving membrane based multiplex immunoassays for semi-quantitative detection of multiple cytokines in a single sample.
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Water-filtered infrared a irradiation in combination with visible light inhibits acute chlamydial infection.
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M-CSF inhibits anti-HIV-1 activity of IL-32, but they enhance M2-like phenotypes of macrophages.
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J Immunol, 2014-04-18;192(11):5083-9. 2014-04-18
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A cannabigerol derivative suppresses immune responses and protects mice from experimental autoimmune encephalomyelitis.
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Identification of novel non-coding RNA-based negative feedback regulating the expression of the oncogenic transcription factor GLI1.
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CCL2 shapes macrophage polarization by GM-CSF and M-CSF: identification of CCL2/CCR2-dependent gene expression profile.
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IGFBP7, a novel tumor stroma marker, with growth-promoting effects in colon cancer through a paracrine tumor-stroma interaction.
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Human adipose-derived stromal/stem cells induce functional CD4+CD25+FoxP3+CD127- regulatory T cells under low oxygen culture conditions.
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Cytokine/chemokine secretion and proteomic identification of upregulated annexin A1 from peripheral blood mononuclear cells cocultured with the liver fluke Opisthorchis viverrini.
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Infect Immun, 2014-03-10;82(5):2135-47. 2014-03-10
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Moraxella catarrhalis adhesin UspA1-derived recombinant fragment rD-7 induces monocyte differentiation to CD14+CD206+ phenotype.
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PLoS ONE, 2014-03-05;9(3):e90999. 2014-03-05
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The biological effect of large single doses: a possible role for non-targeted effects in cell inactivation.
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The RNA chaperone Hfq is involved in stress tolerance and virulence in uropathogenic Proteus mirabilis.
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Leukemia cells induce changes in human bone marrow stromal cells.
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J Transl Med, 2013-12-04;11(0):298. 2013-12-04
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Slit2-Robo4 pathway modulates lipopolysaccharide-induced endothelial inflammation and its expression is dysregulated during endotoxemia.
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J Immunol, 2013-11-22;192(1):385-93. 2013-11-22
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Cold atmospheric plasma (CAP) changes gene expression of key molecules of the wound healing machinery and improves wound healing in vitro and in vivo.
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PLoS ONE, 2013-11-12;8(11):e79325. 2013-11-12
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miR-200b and cancer/testis antigen CAGE form a feedback loop to regulate the invasion and tumorigenic and angiogenic responses of a cancer cell line to microtubule-targeting drugs.
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J Biol Chem, 2013-10-30;288(51):36502-18. 2013-10-30
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DeltaNp63 promotes pediatric neuroblastoma and osteosarcoma by regulating tumor angiogenesis.
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Cancer Res, 2013-10-23;74(1):320-9. 2013-10-23
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Development, characterization, and reversal of acquired resistance to the MEK1 inhibitor selumetinib (AZD6244) in an in vivo model of childhood astrocytoma.
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Gremlin-1 is an inhibitor of macrophage migration inhibitory factor and attenuates atherosclerotic plaque growth in ApoE-/- Mice.
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Anticancer compound ABT-263 accelerates apoptosis in virus-infected cells and imbalances cytokine production and lowers survival rates of infected mice.
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Increased circulation of galectin-3 in cancer induces secretion of metastasis-promoting cytokines from blood vascular endothelium.
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Hypoxia-inducible factor-dependent breast cancer-mesenchymal stem cell bidirectional signaling promotes metastasis.
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LFA-1 and ICAM-1 expression induced during melanoma-endothelial cell co-culture favors the transendothelial migration of melanoma cell lines in vitro.
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BMC Cancer, 2012-10-05;12(0):455. 2012-10-05
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Comparison of endometrial regenerative cells and bone marrow stromal cells.
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Multiplexing immunoassays for cytokine detection in the serum of patients with rheumatoid arthritis: lack of sensitivity and interference by rheumatoid factor.
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Obatoclax, saliphenylhalamide, and gemcitabine inhibit influenza a virus infection.
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Primary tumor hypoxia recruits CD11b+/Ly6Cmed/Ly6G+ immune suppressor cells and compromises NK cell cytotoxicity in the premetastatic niche.
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Cancer Res, 2012-07-02;72(16):3906-11. 2012-07-02
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A novel small molecule, HK-156, inhibits lipopolysaccharide-induced activation of NF-kappaB signaling and improves survival in mouse models of sepsis.
Acta Pharmacol. Sin., 2012-06-11;33(9):1204-16. 2012-06-11
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Characterization of a Mutated IgA2 Antibody of the m(1) Allotype against the Epidermal Growth Factor Receptor for the Recruitment of Monocytes and Macrophages.
Authors: Lohse S, Brunke C, Derer S, Peipp M, Boross P, Kellner C, Beyer T, Dechant M, van der Winkel JG, Leusen JH, Valerius T
J. Biol. Chem., 2012-06-07;287(30):25139-50. 2012-06-07
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Reconstruction of monocyte transcriptional regulatory network accompanies monocytic functions in human fibroblasts.
Authors: Suzuki T, Nakano-Ikegaya M, Yabukami-Okuda H
PLoS ONE, 2012-03-13;7(3):e33474. 2012-03-13
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Anti-inflammatory effects of methoxyphenolic compounds on human airway cells.
Authors: Houser KR, Johnson DK, Ishmael FT
J Inflamm (Lond), 2012-03-13;9(0):6. 2012-03-13
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HIV-1 proteins preferentially activate anti-inflammatory M2-type macrophages.
Authors: Chihara T, Hashimoto M, Osman A, Hiyoshi-Yoshidomi Y, Suzu I, Chutiwitoonchai N, Hiyoshi M, Okada S, Suzu S
J. Immunol., 2012-03-09;188(8):3620-7. 2012-03-09
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Inhibition of IL-32 activation by alpha-1 antitrypsin suppresses alloreactivity and increases survival in an allogeneic murine marrow transplantation model.
Authors: Marcondes AM, Li X, Tabellini L, Bartenstein M, Kabacka J, Sale GE, Hansen JA, Dinarello CA, Deeg HJ
Blood, 2011-09-06;118(18):5031-9. 2011-09-06
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Fine-tuning nucleophosmin in macrophage differentiation and activation.
Authors: Guery L, Benikhlef N, Gautier T, Paul C, Jego G, Dufour E, Jacquel A, Cally R, Manoury B, Vanden Berghe T, Vandenabeele P, Droin N, Solary E
Blood, 2011-08-29;118(17):4694-704. 2011-08-29
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Leptin administered in physiological or pharmacological doses does not regulate circulating angiogenesis factors in humans.
Authors: Aronis KN, Diakopoulos KN, Fiorenza CG
Diabetologia, 2011-06-10;54(9):2358-67. 2011-06-10
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The immunomodulatory role of syncytiotrophoblast microvesicles.
Authors: Southcombe J, Tannetta D, Redman C, Sargent I
PLoS ONE, 2011-05-25;6(5):e20245. 2011-05-25
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Cadherin-11 regulates fibroblast inflammation.
Authors: Chang SK, Noss EH, Chen M, Gu Z, Townsend K, Grenha R, Leon L, Lee SY, Lee DM, Brenner MB
Proc. Natl. Acad. Sci. U.S.A., 2011-05-02;108(20):8402-7. 2011-05-02
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Maternal high-fat diet disturbs uteroplacental hemodynamics and increases the frequency of stillbirth in a nonhuman primate model of excess nutrition.
Authors: Frias AE, Morgan TK, Evans AE
Endocrinology, 2011-03-29;152(6):2456-64. 2011-03-29
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Targeting Galectin-1 in Carcinoma-Associated Fibroblasts Inhibits Oral Squamous Cell Carcinoma Metastasis by Downregulating MCP-1/CCL2 Expression.
Authors: Wu MH, Hong HC, Hong TM, Chiang WF, Jin YT, Chen YL
Clin. Cancer Res., 2011-03-08;17(6):1306-16. 2011-03-08
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Syndecan-1 knock-down in decidualized human endometrial stromal cells leads to significant changes in cytokine and angiogenic factor expression patterns.
Authors: Baston-Bust DM, Gotte M, Janni W, Krussel JS, Hess AP
Reprod. Biol. Endocrinol., 2010-11-02;8(0):133. 2010-11-02
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IL-37 is a fundamental inhibitor of innate immunity.
Authors: Nold MF, Nold-Petry CA, Zepp JA
Nat. Immunol., 2010-10-10;11(11):1014-22. 2010-10-10
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Pancreatic adenocarcinoma upregulated factor promotes metastasis by regulating TLR/CXCR4 activation.
Authors: Park HD, Lee Y, Oh YK, Jung JG, Park YW, Myung K, Kim KH, Koh SS, Lim DS
Oncogene, 2010-08-30;30(2):201-11. 2010-08-30
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Androgen-regulated expression of arginase 1, arginase 2 and interleukin-8 in human prostate cancer.
Authors: Gannon PO, Godin-Ethier J, Hassler M, Delvoye N, Aversa M, Poisson AO, Peant B, Alam Fahmy M, Saad F, Lapointe R, Mes-Masson AM
PLoS ONE, 2010-08-11;5(8):e12107. 2010-08-11
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A role for the human nucleotide-binding domain, leucine-rich repeat-containing family member NLRC5 in antiviral responses.
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J. Biol. Chem., 2010-06-10;285(34):26223-32. 2010-06-10
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Interleukin-27 induces a STAT1/3- and NF-kappaB-dependent proinflammatory cytokine profile in human monocytes.
Authors: Guzzo C, Che Mat NF, Gee K
J. Biol. Chem., 2010-06-02;285(32):24404-11. 2010-06-02
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PI3K/p110{delta} is a novel therapeutic target in multiple myeloma.
Authors: Ikeda H, Hideshima T, Fulciniti M
Blood, 2010-05-26;116(9):1460-8. 2010-05-26
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Chlamydia pneumoniae infection in polarized epithelial cell lines.
Authors: Tormakangas L, Markkula E, Lounatmaa K, Puolakkainen M
Infect. Immun., 2010-03-29;78(6):2714-22. 2010-03-29
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Glucose-induced expression of MIP-1 genes requires O-GlcNAc transferase in monocytes.
Authors: Chikanishi T, Fujiki R, Hashiba W, Sekine H, Yokoyama A, Kato S
Biochem. Biophys. Res. Commun., 2010-03-02;394(4):865-70. 2010-03-02
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Protective effect of human amniotic fluid stem cells in an immunodeficient mouse model of acute tubular necrosis.
Authors: Perin L, Sedrakyan S, Giuliani S, Da Sacco S, Carraro G, Shiri L, Lemley KV, Rosol M, Wu S, Atala A, Warburton D, De Filippo RE
PLoS ONE, 2010-02-24;5(2):e9357. 2010-02-24
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Changes in melanocortin expression and inflammatory pathways in fetal offspring of nonhuman primates fed a high-fat diet.
Authors: Grayson BE, Levasseur PR, Williams SM, Smith MS, Marks DL, Grove KL
Endocrinology, 2010-02-22;151(4):1622-32. 2010-02-22
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Human CD4- 8- T cells are a distinctive immunoregulatory subset.
Authors: Huang MC, Patel K, Taub DD, Longo DL, Goetzl EJ
FASEB J, 2010-02-12;24(7):2558-66. 2010-02-12
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Alpha-defensins secreted by dysplastic granulocytes inhibit the differentiation of monocytes in chronic myelomonocytic leukemia.
Authors: Droin N, Jacquel A, Hendra JB, Racoeur C, Truntzer C, Pecqueur D, Benikhlef N, Ciudad M, Guery L, Jooste V, Dufour E, Fenaux P, Quesnel B, Kosmider O, Fontenay M, Ducoroy P, Solary E
Blood, 2009-10-28;115(1):78-88. 2009-10-28
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Macrophage-derived IL-1beta stimulates Wnt signaling and growth of colon cancer cells: a crosstalk interrupted by vitamin D3.
Authors: Kaler P, Augenlicht L, Klampfer L
Oncogene, 2009-08-24;28(44):3892-902. 2009-08-24
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Glioblastoma and endothelial cells cross-talk, mediated by SDF-1, enhances tumour invasion and endothelial proliferation by increasing expression of cathepsins B, S, and MMP-9.
Authors: Kenig S, Alonso MB, Mueller MM, Lah TT
Cancer Lett., 2009-08-22;289(1):53-61. 2009-08-22
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Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease.
Authors: Smith AM, Rahman FZ, Hayee B, Graham SJ, Marks DJ, Sewell GW, Palmer CD, Wilde J, Foxwell BM, Gloger IS, Sweeting T, Marsh M, Walker AP, Bloom SL, Segal AW
J. Exp. Med., 2009-08-03;206(9):1883-97. 2009-08-03
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ADA-deficient SCID is associated with a specific microenvironment and bone phenotype characterized by RANKL/OPG imbalance and osteoblast insufficiency.
Authors: Sauer AV, Mrak E, Hernandez RJ, Zacchi E, Cavani F, Casiraghi M, Grunebaum E, Roifman CM, Cervi MC, Ambrosi A, Carlucci F, Roncarolo MG, Villa A, Rubinacci A, Aiuti A
Blood, 2009-07-24;114(15):3216-26. 2009-07-24
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Identification of macrophage migration inhibitory factor and human neutrophil peptides 1-3 as potential biomarkers for gastric cancer.
Authors: Mohri Y, Mohri T, Wei W, Qi YJ, Martin A, Miki C, Kusunoki M, Ward DG, Johnson PJ
Br. J. Cancer, 2009-06-23;101(2):295-302. 2009-06-23
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Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells.
Authors: Eid RE, Rao DA, Zhou J, Lo SF, Ranjbaran H, Gallo A, Sokol SI, Pfau S, Pober JS, Tellides G
Circulation, 2009-03-02;119(10):1424-32. 2009-03-02
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Prostate cancer promotes CD11b positive cells to differentiate into osteoclasts.
Authors: Mizutani K, Sud S, Pienta KJ
J. Cell. Biochem., 2009-03-01;106(4):563-9. 2009-03-01
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In vitro neutralization of tumor necrosis factor-alpha during Chlamydia pneumoniae infection impairs dendritic cells maturation/function and increases chlamydial progeny.
Authors: Njau F, Wittkop U, Rohde M, Haller H, Klos A, Wagner AD
FEMS Immunol. Med. Microbiol., 2009-03-01;55(2):215-25. 2009-03-01
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Vascular endothelial growth factor induces protein kinase D-dependent production of proinflammatory cytokines in endothelial cells.
Authors: Hao Q, Wang L, Tang H
Am. J. Physiol., Cell Physiol., 2009-01-28;296(4):C821-7. 2009-01-28
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Soluble CD40 ligand as a biomarker for storage-related preanalytic variations of human serum.
Authors: Lengelle J, Panopoulos E, Betsou F
Cytokine, 2008-10-11;44(2):275-82. 2008-10-11
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Co-cultures of multiple cell types mimic pulmonary cell communication in response to urban PM10.
Authors: Alfaro-Moreno E, Nawrot TS, Vanaudenaerde BM, Hoylaerts MF, Vanoirbeek JA, Nemery B, Hoet PH
Eur. Respir. J., 2008-07-24;32(5):1184-94. 2008-07-24
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Endogenous IL-32 controls cytokine and HIV-1 production.
Authors: Nold MF, Nold-Petry CA, Pott GB, Zepp JA, Saavedra MT, Kim SH, Dinarello CA
J. Immunol., 2008-07-01;181(1):557-65. 2008-07-01
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Agonists of proteinase-activated receptor-2 enhance IFN-gamma-inducible effects on human monocytes: role in influenza A infection.
Authors: Feld M, Shpacovitch VM, Ehrhardt C, Kerkhoff C, Hollenberg MD, Vergnolle N, Ludwig S, Steinhoff M
J. Immunol., 2008-05-15;180(10):6903-10. 2008-05-15
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Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function.
Authors: Marcondes AM, Mhyre AJ, Stirewalt DL, Kim SH, Dinarello CA, Deeg HJ
Proc. Natl. Acad. Sci. U.S.A., 2008-02-19;105(8):2865-70. 2008-02-19
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IL-1beta-stimulated activation of ERK1/2 and p38alpha MAPK mediates the transcriptional up-regulation of IL-6, IL-8 and GRO-alpha in HeLa cells.
Authors: Yang HT, Cohen P, Rousseau S
Cell. Signal., 2007-11-07;20(2):375-80. 2007-11-07
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Dasatinib, a small-molecule protein tyrosine kinase inhibitor, inhibits T-cell activation and proliferation.
Authors: Schade AE, Schieven GL, Townsend R, Jankowska AM, Susulic V, Zhang R, Szpurka H, Maciejewski JP
Blood, 2007-10-25;111(3):1366-77. 2007-10-25
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Annexin A2 is a soluble mediator of macrophage activation.
Authors: Swisher JF, Khatri U, Feldman GM
J. Leukoc. Biol., 2007-08-22;82(5):1174-84. 2007-08-22
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A paracrine role for chemoattractant receptor-homologous molecule expressed on T helper type 2 cells (CRTH2) in mediating chemotactic activation of CRTH2+ CD4+ T helper type 2 lymphocytes.
Authors: Vinall SL, Townsend ER, Pettipher R
Immunology, 2007-04-16;121(4):577-84. 2007-04-16
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Induction of host chemotactic response by Encephalitozoon spp.
Authors: Fischer J, West J, Agochukwu N, Suire C, Hale-Donze H
Infect. Immun., 2006-12-18;75(4):1619-25. 2006-12-18
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